2 nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

Synopsis

Atherosclerosis and its complications remain the major cause of death in the industrialized world and emerging economies worldwide. Dyslipidemia constitutes a major risk factor for the development and progression of atherosclerotic lesions, but may also lead to systemic disturbances - particularly metabolic dysfunction - that also influence cellular metabolism and function. Atherosclerotic lesions formation is initiated after retention of cholesterol-rich lipoproteins within the arterial wall at sites characterized by low shear stress. Modification of retained lipoproteins and activation of endothelial and vascular smooth muscle cells trigger an inflammatory response and provoke a series of cellular events involving complex interactions between vascular cells, innate immune cells (e.g., neutrophils, monocytes/macrophages, dendritic cells, mast cells, B1 B lymphocytes, innate lymphoid cells) and cells involved in adaptive immunity to atherosclerosis-related antigens (e.g., Th1, Tregs, B2 lymphocytes). Depending on the balance between pro-inflammatory responses and resolution promoting pathways, lesion development is either delayed or accelerated towards the formation of advanced and complex plaques characterized by chronic unresolved inflammation, extensive matrix remodelling and formation of large thrombogenic necrotic cores. Defective repair and weakening of the protective fibrous cap ultimately leads to plaque disruption, which triggers acute thrombosis and vascular occlusion.

The goal of this meeting is to provide attendees with a comprehensive overview of current research on atherosclerosis with a focus on the latest and most exciting developments in the immuno-metabolic mechanisms that govern disease initiation and progression. There is little doubt that the next most exciting therapy to combat cardiovascular disease will be based on targeting biological pathways that will have been discussed during this conference.

Seven sessions are planned and will highlight the following major research areas:

vessel wall and endothelial cell biology
lipids and modified lipids in inflammation
cellular lipid metabolism and immunity
lipoproteins and immune regulation
extracellular vesicles
innate immunity and metabolic regulation of innate immune functions
epigenetics and regulation of gene expression in immune cells
mechanisms involving inflammasome activation of monocyte/macrophages
trained immunity, pro- and anti-atherogenic mechanisms operated by selective subsets of T and B lymphocytes
immunometabolism and lymphocytes
aging and senescence in inflammation, hematopoiesis, and cardiovascular disease
non coding RNAs in lipid metabolism and inflammation
existing and validated targets that are now in late-phase clinical trials.

This conference will bring together a restricted but high-level group of scientists from different disciplines and participants from all career levels enabling thorough discussions of the latest research between established and young investigators and trainees, and cross-fertilization among scientists from a variety of backgrounds.

Ziad Mallat, Christoph Binder, and Eicke Latz (Co-Chairs) look forward to welcoming you to the Melia Nassau Beach, Nassau, The Bahamas, from March 1-4, 2020.

Key Sessions

Vessel wall and endothelial cells
Lipids and extracellular vesicles
Innate immunity and inflammasome
Adaptive immunity
Aging and senescence
Genetics and gene regulation
Microbiome

Student Offer

Take advantage of this fantastic opportunity for students! Any fully paying academic can bring a student for only $850. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 01, 02, 03 March 2020 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Once registered, please contact Chloe Trundle to obtain a special registration link for your student.

Confirmed Invited Speakers

Nicolas Bazan (LSU Health New Orleans)
Peter Carmeliet (VIB)
ANGIOGENESIS REVISITED: ROLE AND (THERAPEUTIC) IMPLICATIONS OF ENDOTHELIAL METABOLISM
Navdeep Chandel (Northwestern University)
MITOCHONDRIA AS SIGNALING ORGANELLES
Vishwa Deep Dixit (Yale School of Medicine)
IMMUNOMETABOLIC CONTROL OF HEALTHSPAN
Benjamin Ebert (Dana-Farber Cancer Institute)
CLONAL HEMATOPOIESIS AND CARDIOVASCULAR DISEASE
Zahi Fayad (Icahn School of Medicine at Mount Sinai)
IMMUNO-IMAGING AND IMMUNOTHERAPY IN ATHEROSCLEROSIS
Carlos Fernandez-Hernando (Yale School of Medicine)
IMMUNOMODULATORY ACTIONS OF CHOLESTEROL BIOSYNTHETIC INTERMEDIATES ON MACROPHAGE ACTIVATION DURING ATHEROSCLEROSIS
Chris Glass (University of California, San Diego)
MECHANISMS DRIVING MYELOID CELL DIVERSITY IN IMMUNO-METABOLIC DISEASE
Claudia Kemper (National Heart, Lung, and Blood Institute)
THE COMPLOSOME IN THE REGULATION OF T CELL METABOLISM
Klaus Ley (La Jolla Institute for Immunology)
SINGLE BLOOD CELL TRANSCRIPTOMICS OF CARDIOVASCULAR DISEASE IN HUMANS
Peter Libby (Brigham and Women’s Hospital)
CHALLENGE IN MOVING IMMUNOLOGY AND INFLAMMATION IN ATHEROSCLEROSIS TO THE CLINIC
Musa Mhlanga (University of Cape Town)
EPIGENETICS OF TRAINED IMMUNITY
Kathryn Moore (NYU School of Medicine)
INNATE IMMUNE REPROGRAMMING IN CARDIOVASCULAR DISEASE
Mihai Netea (Radboud University)
TRAINED IMMUNITY IN HEALTH AND INFLAMMATORY DISEASES
Luke O'Neill (Trinity College Dublin)
IMMUNOMETABOLISM AT THE HEART OF INNATE IMMUNITY AND INFLAMMATION
William Sessa (Yale School of Medicine)
ENDOTHELIAL CHOLESTEROL UPTAKE AND METABOLISM
Filip Swirski (MGH Harvard)
LIFESTYLE, IMMUNOMETABOLISM, AND ATHEROSCLEROSIS
Alan Tall (Columbia University)
MECHANISMS OF ATHERO-THROMBOSIS IN CLONAL HEMATOPOIESIS
Clotilde Théry (Institut Curie)
EXOSOMES AND OTHER EXTRACELLULAR VESICLES AS REGULATORS OF MACROPHAGE FUNCTIONS
Jan van Deursen (Mayo Clinic)
HOW SENESCENT CELLS DRIVE ATHEROGENESIS

Target Audience

We encourage young scientists/clinicians to attend and expect broad representation from various disciplines. The conference will especially appeal to scientists, scientists/clinicians in academia, biotech and pharmaceutical companies with interest in Cardiovascular Medicine/Biology, Immunology, Metabolic Diseases, Immuno-Metabolism, Molecular/Cellular Biology and Epigenetics.

Educational Need

Graduate students, postdocs and junior researchers will gain a cutting-edge overview of the field and will have the extraordinary opportunity to discuss the latest developments with world-leading experts in an informal and highly conducive setting.

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Speakers

Invited Speakers

Mihai Netea

Professor, Radboud University Medical Center

Chris Glass

Professor, UC San Diego

Kathryn Moore

Professor, New York University

Luke O'Neill

Professor, Trinity College Dublin

Jan van Deursen

Professor and Chair, Mayo Clinic

Peter Carmeliet

Group Leader Laboratory of Angiogenesis & Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology

Navdeep Chandel

Professor of Medicine, Feinberg School of Medicine, Northwestern University

Alan Tall

Professor, Columbia University Medical Center

Benjamin Ebert

Chair, Medical Oncology, Dana-Farber Cancer Institute

Claudia Kemper

Senior Investigator, National Institutes of Health

Clotilde Théry

PI, Institut Curie/INSERMU932

Filip Swirski

Associate Professor, Massachusetts General Hospital and Harvard Medical School

Zahi Fayad

Director, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai

Klaus Ley

Professor and Head, La Jolla Institute For Immunology

Carlos Fernandez-Hernando

Professor, Yale University School of Medicine

Vishwa Dixit

Professor, Yale School of Medicine

William Sessa

Professor, Yale School of Medicine

Musa Mhlanga

Professor, University of Cape Town, Faculty of Health Sciences

Peter Libby

Cardiovascular Specialist, Brigham and Women’s Hospital

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Programme

Although the programme has not yet been released, we are able to confirm that the conference should begin no earlier than 14:45 with opening comments on 1st March 2020. Registration and a welcome reception should be available from 14:00. The conference will conclude no later than 12:30 on 4th March 2020.

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Prices

	Early Bird	Full Price	Additional Adult	Additional Child	Extra Night Adult	Extra Night Child
Academic	$1845	$1945	$684	$263	$321	$88
Industry	$1845	$1945	$684	$263	$321	$88
Student	$1556	$1656	$684	$263	$321	$88

All registration fees include 3 nights accomodation and meals during the conference period. Exact inclusions are detailed below.

What's Included in our Registration Fees?

Our registration fees are inclusive of the following during the conference period only:

- Conference registration
- 3 Nights’ fixed accommodation (01, 02, 03 March 2020) on a single basis for academics and industry, on a shared basis for students/Postdocs
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Gala Dinner (includes an open bar)
- Room service
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in both conference rooms and your guest room

What's Included in our Accompanying Adult Fees?

Our accompanying adult fees are inclusive of the following during the conference period only:

- 3 Nights’ fixed accommodation (01, 02, 03 March 2020) on a shared basis with a conference participant
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Gala Dinner (includes an open bar)
- Room service
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Accompanying persons are not permitted access to the conference.

What's Included in our Accompanying Child Fees?

Our accompanying child fees are inclusive of the following during the conference period only:

- 3 Nights’ fixed accommodation (01, 02, 03 March 2020) on a shared basis with the parent/s
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited bottled water and soft drinks
- Gala Dinner
- Room service
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Accompanying child fees are applicable for children aged 2-12 years. Children younger than 2 years stay free of charge with a parent. Children aged 13-17 years will be charged $377 per child. 18 years + will be classified as an adult at this venue (Melia Nassau Beach, Bahamas). Please kindly ensure your child / children are supervised at all times during conference and related events. Childcare services are available at the hotel, please contact Chloe Trundle for further information.

What's Included in our Extra Night Fees?

- 1 night’s accommodation for 1 person
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Room service
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Extra night child fees are applicable for children aged 2-12 years. Children younger than 2 years stay free of charge with a parent. Children aged 13-17 years will be charged $126 per night, per child. 18 years + will be classified as an adult at this venue (Melia Nassau Beach, Bahamas).

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

LinkedIn forum

The Atherosclerosis Research Network LinkedIn group is an excellent platform to connect with fellow attendees and likeminded researchers prior to the conference. The group is open to all and is intended as a networking forum for past, present and future participants of Fusion Conferences as well as those interested in the related topics. To join, please follow the link below.

Join our group

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Venue

Melia Nassau Beach All Inclusive

Venue Rating

Currency

US Dollar (USD)

Address

Nassau W Bay St. Nassau Bahamas

Nearest Airport

Lynden Pindling International Airport

Overlooking one of the finest beaches in the world the Meliá Nassau Beach is surrounded by crystal blue waters and white sandy beaches. Located on the stunning Cable Beach, you are just a few minutes walk from the center, shops and restaurants. The beautiful Nassau Botanical Gardens are within easy reach (7km) and Lynden Pindling International Airport is situated only 9km away.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from Cilantro where you can experience the natural textures, aromas and flavors of Mexico, Nikkei, celebrated for its exquisite fusion of Japanese, Cantonese and Peruvian cuisine featuring a sushi bar and Teppanyaki tables, Estavida, an upbeat tapas lounge located in the hotel lobby serving innovative tapas and a wide selection of cocktails, Aqua, an A la carte restaurant specializing in exquisite, rustic Italian cuisine, The Market Place, where you will find an International buffet serving an array of exquisite dishes, O'Grille, an open air restaurant with fabulous views of the sea and pool serving casual beach fare and light bites and finally The Black Angus, a steakhouse featuring hip, contemporary jazz and modern decor, offering guests the finest quality prime cuts and the freshest ingredients.(This restaurant is not included in the all inclusive package, additional charges apply). The Gala Night takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

24 hour reception
Room service
3 heated outdoor pools
Complimentary resort wide Wi-Fi (guest rooms, throughout hotel, beach and conference areas)
24-hour Fitness Center
7 dining venues
4 bars.
non-motorised water sports

The Bahamas is formed by over 700 islands, keys and islets located in the Atlantic Ocean and renowned for its warm sunshine, mild climate, fine, white sandy beaches, turquoise, crystal clear water and friendly people, making this the perfect environment to relax and unwind in your free time during the conference.

Location

The Melia Nassau Beach All-Inclusive is located right on the stunning Cable Beach just a few minutes away from the airport and city center; Nearby in Downtown Nassau you can experience the flavours of new foods at local restaurants, shop 'til you drop at Straw market or take a trip through time at the Pirates Museum. The beautiful Nassau Botanical Gardens are close by and water enthusiasts can enjoy non-motorized water sports right on property.

Nassau is the capital of the Bahamas. It lies on the island of New Providence, with neighboring Paradise Island accessible via Nassau Harbor bridges. The city has a hilly landscape and is known for it's fabulous beaches as well as its offshore coral reefs, popular for diving and snorkeling. It retains many of its typical pastel-colored British colonial buildings, like the pink-hued Government House.

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Transportation

The Melia Nassau Beach Resort is located just 9km from Lynden Pindling International Airport, approximately 10-15 minutes journey time. Formerly known as Nassau International Airport, it is the largest airport in the Bahamas and provides an international gateway into the country.

Taxis

There’s no shortage of available taxi cabs at Lynden Pindling International Airport. Taxis are available outside the U.S., International and Domestic terminals. Taxis charge approximately $25 one way to the Melia Nassau Hotel, however charges may increase if there are more than two passengers and/or two large suitcases.

Pre-Booked Airport Transfers

There are various suppliers that offer pre-booked airport transfer services to and from Lynden Pindling Airport. Please find details of a few that we are aware of below. However, should you require further information or would like to make a booking, please contact the company directly. Pre-booked transportation prices range from $70 - $145 one way.

Simon's Transports Ltd
Contact Name: Jocelyne Casimir
Contact Email: info@simonstransports.com
Website: https://simonstransportsbahamas.com/nassau-airport-transfers/

Majestic Tours
Contact Name: Betty Fox
Contact Email: betty@MajesticHolidays.com
Website: http://www.majestictoursbahamas.com/

Cheryl Bahamas Taxi & Tours
Contact Email: cherylfoxferguson@live.com
Website: http://www.cherylbahamastaxiandtours.com/

Black Diamond Transportation (BDT Bahamas)
Website: https://bdtbahamas.com

**Any bookings and transactions made with the above suppliers are the sole responsibility of the individual.

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Local Activities

Several free activities are available within the resort and include:

Trip to Balmoral Island during your stay; a taxi boat to and from Balmoral Island and access to the VIP Balmoral Beachside is included. Please ask reception for the boat departure/return schedule.
Daily fitness activities: gym classes, yoga, zumba, pool aerobics, etc.
In the water: paddleboards, glass-bottom kayaks, ocean duo kayaks, reef-board zayaks, cabana floating mats, water hammocks, etc.
Workshops: jewellery making, henna tattoo, scent creation, Bahamian crafts, etc.
Classes: mixology, scuba diving, dancing, etc.
Friendly competitions: beach volleyball, beach soccer, ping pong, darts, water balloon toss, deep dive contest, etc.
Free shuttle to Baha Mar and direct access to its spectacular 100,000 sq. ft. casino, Royal Blue™ tournament player’s golf course with special rates for Meliá guests, tennis court, spa, retail outlets and over 30 dining venues and lounges.

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Group Activities

Unfortunately, due to the recent shark attacks, we will no longer be offering a group snorkelling trip for our conferences in the Bahamas next year.

For those of you who still wish to enjoy tours/excursions outside of the resort during free time, Majestic Tours is a local tour operator offering individual or small group trips which can be pre-booked or organised through their hospitality desk within the hotel. For more information, please contact Majestic Tours directly.

Majestic Tours
Contact Name: Betty Fox
Contact Email: betty@MajesticHolidays.com
Website: http://www.majestictoursbahamas.com/

A number of free activities are also available within the resort, please visit our ‘Local Activities’ tab for more information.

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Childcare

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Oral Presenters

We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.

Your Presentation

On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.

Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.

We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.

Please make sure your presentation adheres to the following guidelines.

Aspect Ratio: On Screen Show (16:9)
File Type: Please save your presentation in PPT, PPTS or Keynote format.

Download Abstract Template

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs

Posters

We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you.

Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.

Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.

Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.

Download Abstract Template

Supported By

Diamond

Bronze

Endorsing Partners

Media Partners

If you're interested in sponsoring this conference please contact us.

2^nd Immuno-Metabolic Mechanisms of Atherosclerosis Conference

#IMMA20

01 Mar 2020 - 04 Mar 2020

Nassau, Bahamas

Chairs