Urgent Notice to All Conference Participants

It has been brought to our attention that EHS Housing has recently been cold calling our speakers offering accommodation for a named Fusion conference. Please note that we have no association with EHS Housing and they are acting on our behalf without our permission. We strongly advise that any calls from EHS Housing are ignored or ended immediately. If you are contacted by EHS Housing, please notify us immediately.

All Fusion registration fees are inclusive of accommodation (for three fixed nights) and reservations are handled internally, entirely by Fusion Conferences. If you have any questions concerning your accommodation, please contact Fusion Conferences directly via admin@fusion-conferences.com.

Home > Past Conferences >

Spatial Genome Organization Conference

The registration process for this conference has now closed.

Registration Deadlines

Early bird – expired

Talk Submission – expired

Poster Submission – expired

Last Chance – expired

Spatial Genome Organization Conference

The Nucleome in Basic Biology and Disease

25 Feb 2019 - 28 Feb 2019

Nassau, Bahamas

The conference registration date has past

Synopsis

Spatial Genome Organization Conference Frontiers Research Topic

The conference will bring together scientists working to better understand three-dimensional genome organization in various organisms, tissues, and cell states. 

Key Sessions 

  • Structure and function of subnuclear domains
  • Topogically Associated Domains (TADs) and similar domains
  • Signalling cues, cellular states and genome organization
  • DNA damage and spatial genome organization
  • Genome structure in health and disease
  • Workshop I: Genome editing and super-resolution microscopy
  • Workshop II: Chromosome conformation capture, sequencing and databases
  • Workshop III: Young scientists in the era of spatial genome organization, how to get published?

Student Offer

Take advantage of this fantastic opportunity for students! Register an academic at the standard rate of $1,922 and bring a student for only $850. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 25, 26, 27 February 2019 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Academic registrations must be completed by 14 December 2018. Once registered, please contact Meredith Willmott to obtain a special registration link for your student.

Confirmed Plenary Speakers: 

Andrés Aguilera (University of Seville)
ROLE OF CHROMATIN AND DNA DAMAGE RESPONSE FUNCTIONS IN R LOOP-MEDIATED GENOME INSTABILITY
Wendy Bickmore (The University of Edinburgh)
THE REMOTE CONTROL OF GENE EXPRESSION
Daniel Durocher (The Lunenfeld-Tanenbaum Research Institute)
CHARTING THE GENETIC ARCHITECTURE OF THE DNA DAMAGE RESPONSE
Peter Fraser (The Babraham Institute/Florida State University)
Tom Misteli (National Cancer Institute)
HIGH-THROUGHPUT IMAGING TO PROBE HUMAN GENOME ARCHITECTURE

Confirmed Invited Speakers: 

Uttiya Basu (Columbia University) 
DYNAMICS OF TAD INTERACTIONS DURING ANTIBODY GENE DIVERSIFICATION
Irene Chiolo 
(University of Southern California)
HIGHWAYS FOR REPAIR: NUCLEAR ACTIN FILAMENTS AND MYOSINS RELOCALIZE HETEROCHROMATIC DNA BREAKS TO THE NUCLEAR PERIPHERY
Jennifer Cobb (University of Calgary)
SMC5/6 TETHERS rDNA REPEATS AT THE NUCLEAR PERIPHERY
Philippe Collas (University of Oslo)
DYNAMIC TAD CLIQUES SHAPE THE 4D NUCLEOME DURING DIFFERENTIATION
Damien D'Amours (University of Ottawa)
AN UNEXPECTED ROLE FOR MICROTUBULES IN THE CELLULAR RESPONSE TO REPLICATION STRESS
Sérgio De Almeida (Instituto de Medicina Molecular) 
IMAGING DNA BREAK-INDUCED TRANSCRIPTION IN LIVE CELLS
Vincent Dion (UK Dementia Research Institute at Cardiff University)
DNA-DNA CONTACTS REMAIN STABLE UPON CAG/CTG REPEAT EXPANSION 
Emmanuelle Fabre (Inserm)
CHROMOSOME MOBILITY AND GENOME INTEGRITY: WHAT WE ARE LEARNING FROM BUDDING YEAST
Jean Gautier (Columbia University)
GENERATION OF DNA DOUBLE-STRAND BREAK REPAIR DOMAINS
Rajan Jain (Perelman School of Medicine)
INVESTIGATING THE ROLE OF NUCLEAR LAMINA-CHROMATIN INTERACTIONS DURING PROGRESSIVE LINEAGE RESTRICTION AND DISEASE
Megan King (Yale School of Medicine)
DNA DOUBLE-STRAND BREAK REPAIR MECHANISM CHOICE, EFFICIENCY AND OUTCOME: IMPACTS OF CHROMATIN DYNAMICS AND SUBNUCLEAR COMPARTMENTS
Brooke La Flamme (Springer Nature)
AN EDITOR’S PERSPECTIVE ON MAXIMIZING THE IMPACT OF YOUR NEXT MANUSCRIPT
Stephen Lee (University of Miami)
SPATIAL REMODELLING OF THE NUCLEOLUS BY LOW COMPLEXITY RNA
Francisca Lottersberger (Linköping University)
NUCLEAR ARCHITECTURE INFLUENCES CHROMATIN MOBILITY AND DNA DAMAGE REPAIR
Marina Lusic (Heidelberg University Hospital)
Manuel Mendoza (IGBMC)
CONTROL OF CELL IDENTITY BY NUCLEAR PORE ACETYLATION
Thomas Sexton (Institute of Genetics and Molecular and Cellular Biology)
FUNCTIONAL CHROMATIN LOOPS: IS IT ALL JUST CTCF AND ENHANCERS?
Juanma Vaquerizas (Max Planck Insitute)
CHROMATIN CONFORMATION DURING EARLY EMBRYONIC DEVELOPMENT
Richard Wozniak (University of Alberta)
SUMOYLATION AS A REGULATOR OF CHROMATIN ASSOCIATION WITH THE NUCLEAR ENVELOPE
Chao-ting Wu (Harvard Medical School)
LOOKING AT CHROMOSOMES
Christophe Zimmer (Institut Pasteur) 
COMPUTATIONAL IMAGING AND MODELING APPROACHES FOR NUCLEAR BIOPHYSICS

Target Audience

This conference should be of interest to individuals seeking to understand the basic principles of spatial genome organization and how the disruption of this organization impacts health and disease. Those interested in learning or developing new technologies that help reveal more of the secrets of spatial genome organization should both benefit from and greatly enrich the conference. Attendees are expected to have a background in the basics of genetics, nuclear organization, microscopy, and sequencing.

Educational Need

There is a need for an international yet focused conference that brings together people interested in better characterizing the non-random organization of the genome while also revealing how this organization is influenced by various cues or disease conditions. Currently, these topics are typically addressed in a small session of other conferences but the field of spatial genome organization has grown substantially over the past two decades warranting the creation of a dedicated and continuous conference. It is also important that this conference cooperates with yet remains organizationally independent of the various spatial genome organization research networks that have been emerging in some countries.

 

 

Sponsors

Sponsors

Programme

MONDAY 25TH FEBRUARY 2019

14:00 – 15:00

Registration & Welcome Reception

Nuclear and Subnuclear Structure and Function 
Session Chair: Peter Fraser

15:00 – 15:10

Opening Comments

15:10 – 15:45

Plenary: Tom Misteli 
National Cancer Institute

HIGH-THROUGHPUT IMAGING TO PROBE HUMAN GENOME ARCHITECTURE

15:45 – 16:10

Chair: Karim Mekhail 
University of Toronto

INTERGENIC NON-CODING RNAS IN GENOME STRUCTURE AND FUNCTION

16:10 – 16:35

Richard Wozniak 
University of Alberta

SUMOYLATION AS A REGULATOR OF CHROMATIN ASSOCIATION WITH THE NUCLEAR ENVELOPE

16:35 – 17:00

Stephen Lee 
University of Miami

SPATIAL REMODELLING OF THE NUCLEOLUS BY LOW COMPLEXITY RNA

17:00 – 17:25

Emmanuelle Fabre 
INSERM

CHROMOSOME MOBILITY AND GENOME INTEGRITY: WHAT WE ARE LEARNING FROM BUDDING YEAST

17:25 – 18:10

Refreshments

18:10 – 18:35

Matthias Altmeyer 
University of Zurich

PHASE SEPARATION OF 53BP1 ASCERTAINS LIQUID-LIKE BEHAVIOR OF DNA REPAIR COMPARTMENTS

18:35 – 18:50

Nicole Hustedt 
The Lunenfeld Tanenbaum Research Institute

GENOME-WIDE CRISPR/CAS9 SCREENS SHED LIGHT ON DNA REPAIR MECHANISM

18:50 – 19:05

Pedro Rocha 
NIH/ NICHD

ANALYSIS OF 3D GENOMIC INTERACTIONS IDENTIFIES CANDIDATE HOST GENES THAT TRANSPOSABLE ELEMENTS POTENTIALLY REGULATE

19:05 – 19:20

Duygu Yilmaz 
IGBMC

CENTROMERIC CHROMATIN PERMITS DOUBLE STRAND BREAK REPAIR BY HOMOLOGOUS RECOMBINATION IN G1

19:20 – 19:50

Meet the Poster Presenters 
Moderator: Karim Mekhail

19:50

Dinner

TUESDAY 26TH FEBRUARY 2019

07:00 – 09:00

Buffet Breakfast at The Market Place

Topologically Associated Domains and Transcription in Genome Control 
Session Chair: Tom Misteli

09:00 – 09:35

Plenary: Peter Fraser 
Florida State University

CHROMOSOME DYNAMICS IN PRE-IMPLANTATION DEVELOPMENT

09:35 – 10:00

Philippe Collas 
University of Oslo

DYNAMIC TAD CLIQUES SHAPE THE 4D NUCLEOME DURING DIFFERENTIATION

10:00 – 10:25

Chao-ting Wu 
Harvard Medical School

LOOKING AT CHROMOSOMES

10:25 – 11:10

Group Photo, Refreshments & Poster Viewing

11:10 – 11:35

Uttiya Basu 
Columbia University

DYNAMICS OF TAD INTERACTIONS DURING ANTIBODY GENE DIVERSIFICATION

11:35 – 12:00

Sérgio De Almeida 
Instituto de Medicina Molecular

IMAGING DNA BREAK-INDUCED TRANSCRIPTION IN LIVE CELLS

12:00 – 16:50

Lunch at Leisure & Free Time

12:45 – 16:00

Group Activity: Snorkel Trip (sign-ups required in advance)

Signaling Cues, Cellular States and Genome Organization 
Session Chair: Daniel Durocher

16:50 – 17:25

Plenary: Wendy Bickmore 
MRC Human Genetics Unit

THE REMOTE CONTROL OF GENE EXPRESSION

17:25 – 17:50

Damien D’Amours 
University of Ottawa

AN UNEXPECTED ROLE FOR MICROTUBULES IN THE CELLULAR RESPONSE TO REPLICATION STRESS

17:50 – 18:15

Jennifer Cobb 
University of Calgary

SMC5/6 TETHERS rDNA REPEATS AT THE NUCLEAR PERIPHERY

18:15 – 19:45

Poster Session & Refreshments

19:45

Dinner

WEDNESDAY 27TH FEBRUARY 2019

07:00 – 09:00

Buffet Breakfast at The Market Place

Genome Dynamics in DNA Repair 
Session Chair: Wendy Bickmore

09:00 – 09:25

Co-Chair: Evi Soutoglou 
IGBMC

DOUBLE STRAND BREAK RELOCATION CORRELATES WITH HETEROCHROMATIC REPEAT CLUSTERING

09:25 – 09:40

Roxanne Oshidari 
University of Toronto

NUCLEAR MICROTUBULE FILAMENTS IN DAMAGED DNA MOBILITY AND REPAIR

09:40 – 10:05

Francisca Lottersberger 
Linköping University

NUCLEAR ARCHITECTURE INFLUENCES CHROMATIN MOBILITY AND DNA DAMAGE REPAIR

10:05 – 10:30

Irene Chiolo 
University of Southern California

HIGHWAYS FOR REPAIR: NUCLEAR ACTIN FILAMENTS AND MYOSINS RELOCALIZE HETEROCHROMATIC DNA BREAKS TO THE NUCLEAR PERIPHERY

10:30 – 11:15

Refreshments & Poster Viewing

11:15 – 11:40

Jean Gautier 
Columbia University Medical Center

GENERATION OF DNA DOUBLE-STRAND BREAK REPAIR DOMAINS

11:40 – 12:05

Megan King 
Yale School of Medicine

DNA DOUBLE-STRAND BREAK REPAIR MECHANISM CHOICE, EFFICIENCY AND OUTCOME: IMPACTS OF CHROMATIN DYNAMICS AND SUBNUCLEAR COMPARTMENTS

12:05 – 12:20

Andrew Seeber 
Harvard University

CHROMOSOME DYNAMICS IN RESPONSE TO DNA DAMAGE

12:20 – 16:30

Lunch at Leisure & Free Time

Genome Organization in Health, Aging and Disease 
Session Chair: Andrés Aguilera

16:30 – 17:05

Plenary: Daniel Durocher 
The Lunenfeld-Tanenbaum Research Institute

CHARTING THE GENETIC ARCHITECTURE OF THE DNA DAMAGE RESPONSE

17:05 – 17:20

Effie Apostolou 
Weill Cornell Medicine

KLF4 BINDING DURING REPROGRAMMING IS INVOLVED IN 3D ARCHITECTURAL REWIRING AN DTRANSCRIPTIONAL REGULATION OF ENHANCER HUBS

17:20 – 17:45

Manuel Mendoza 
IGBMC

CONTROL OF CELL IDENTITY BY NUCLEAR PORE ACETYLATION

17:45 – 18:00

Lauren Ostrowski 
University of Toronto

NEURODEGENERATION-LINKED POLYGLUTAMINE EXPANSION CONNECTS PROTEIN AGGREGATION, RETROTRANSPOSONS AND rDNA REPEAT STABILITY TO LIFESPAN

18:00 – 18:35

Refreshments & Poster Viewing

18:35 – 19:00

Rajan Jain 
University of Pennsylvania

INVESTIGATING THE ROLE OF NUCLEAR LAMINA-CHROMATIN INTERACTIONS DURING PROGRESSIVE LINEAGE RESTRICTION AND DISEASE

19:00 – 19:25

Vincent Dion 
Dementia Research Institute at Cardiff University

DNA-DNA CONTACTS REMAIN STABLE UPON CAG/CTG REPEAT EXPANSION

19:25 – 19:50

Marina Lusic 
Heidelberg University

WHAT DOES HIV-1 INTEGRATION TELL US ABOUT THE STRUCTURE AND ORGANIZATION OF THE GENOME IN PRIMARY T CELLS?

19:50 – 20:05

Colin Semple 
MRC Human Genetics Unit

BREAKING POINT: COMPUTATIONAL INTERROGATION OF STRUCTURAL VARIATION IN CANCER

20:05

Gala Dinner & Poster Awards

THURSDAY 28TH FEBRUARY 2019

07:00 – 09:00

Buffet Breakfast at The Market Place

Non-Canonical Nucleic Acid Structures and Chromatin Loops in Genome Expression and Stability 
Session Chair: Evi Soutoglou

09:00 – 09:35

Plenary: Andrés Aguilera 
CABIMER/ University of Seville

ROLE OF CHROMATIN AND DNA DAMAGE RESPONSE FUNCTIONS IN R LOOP-MEDIATED GENOME INSTABILITY

09:35 – 10:00

Thomas Sexton 
IGBMC

FUNCTIONAL CHROMATIN LOOPS: IS IT ALL JUST CTCF AND ENHANCERS?

10:00 – 10:25

Juanma Vaquerizas 
Max Planck Institute

CHROMATIN CONFORMATION DURING EARLY EMBRYONIC DEVELOPMENT

10:25 – 10:55

Refreshments

Workshops – Technological Advances and Publishing Trends 
Session Chair: Karim Mekhail

10:55 – 11:20

Brooke LaFlamme 
Springer Nature 
Communications Biology

AN EDITOR’S PERSPECTIVE ON MAXIMIZING THE IMPACT OF YOUR NEXT MANUSCRIPT

11:20 – 11:45

Laure Crabbé 
Center for Integrative Biology

PROBING TELOMERE AND NUCLEAR ENVELOPE INTERACTION USING MADID AND 3D-SIM MICROSCOPY

11:45 – 12:10

Christophe Zimmer 
Institut Pasteur

COMPUTATIONAL IMAGING AND MODELING APPROACHES FOR NUCLEAR BIOPHYSICS

12:10 – 12:25

Magda Bienko 
Karolinska Institute

RADIAL ORGANIZATION OF THE GENOME REVEALED BY GPSEQ

12:25 – 12:35

Closing Comments

Speakers

Plenary Speakers

Invited Speakers

  • Prof. Philippe Collas
    Professor, University of Oslo
  • Assist. Prof. Francisca Lottersberger
    Senior Lecturer, Linköping University
  • Dr. Christophe Zimmer
    Research director, Institut Pasteur
  • Dr. Emmanuelle FABRE
    PI Research Director, INSERM U944
  • Dr. Brooke LaFlamme
    Chief Editor, Springer Nature
  • Dr. Rajan Jain
    Assistant Professor, Perelman School of Medicine, University of Pennsylvania
  • Prof. Vincent Dion
    Professor, Dementia Research Institute at Cardiff University
  • Dr. Marina Lusic
    Group Leader, Heidelberg University Clinic
  • Prof. Dr. Stephen Lee
    Professor of Biochemistry and Molecular Biology , University of Miami
  • Dr. Megan King
    Associate Professor, Yale School of Medicine
  • Dr. Richard Wozniak
    Professor, University of Alberta
  • Prof. Ting (C.-ting) Wu
    Professor, Harvard Medical School
  • Dr. Thomas Sexton
    Team Leader , CERBM GIE
  • Prof. Dr. Damien D'Amours
    Professor, University of Ottawa
  • Dr. Juanma Vaquerizas
    Max Planck Research Group Leader, Max Planck Institute for Molecular Biomedicine
  • Dr. Manuel Mendoza
    TEAM LEADER , IGBMC
  • Dr. Laure Crabbe
    Dr., CNRS UMR 5088
  • Dr. Jennifer Cobb
    Associate Profesor, University of Calgary
  • Dr. Uttiya Basu
    Associate Professor, Columbia University
  • Dr. Jean Gautier
    Professor, Columbia University Medical Center
  • Prof. Irene Chiolo
    Assistant Professor, USC
  • Prof. Sergio de Almeida
    Group Leader, Instituto de Medicina Molecular
  • Assist. Prof. Matthias Altmeyer
    Research Group Leader, University of Zurich

Feedback

Sign In

Your feedback has been received.