Synopsis
Lung development is governed by epithelial-mesenchymal interactions. These pathways are recapitulated during injury and repair. This conference will focus on understanding key processes underlying lung development, injury and repair in the context of age, environment and species, with the hope of better understanding disease development and to discover novel therapeutic approaches.
We will highlight critical issues on lung epithelial biology such as stem cells and regenerative medicine, while expanding sessions to encompass themes such as single cell analytical approaches, cell-cell communication, dissect the biological distinctions mesenchymal proliferation as a repair mechanism and fibrosis; present the impact of new tools in single cell analysis on understanding lung development, repair, and disease; and characterize epithelial-mesenchymal interrelationships that maintain lung homeostasis and orchestrate repair and regeneration. The entire program has been designed to achieve a better understanding of the key clinical research issues and how they relate to basic mechanistic investigation.
Join the conference LinkedIn group to keep up to date with announcements and latest news concerning the conference.
For those interested, this meeting follows the 3rd Fibroblast Growth Factors in Development and Repair Conference, taking place from 15 February - 18 February 2019 at the same venue. A joint FGF session will take place on Monday 18 February from 08:30 - 12:30.
Key Sessions
- Fgf signaling in lung development and fibrosis
- Aging and lung fibrosis
- Lung stem/progenitor cells and their regulation in health and disease
- Organoid cultures to model lung development and disease
- Epithelial-mesenchymal interactions in lung development and fibrosis
Conference Grants
Student Offer
Take advantage of this fantastic opportunity for students! Register an academic at the earlybird rate of $1,822 and bring a student for only $850. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 17th, 18th, 19th Feb 2019 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Once registered, please contact Meredith Willmott to obtain a special registration link for your student.
Confirmed Invited Speakers
Joseph Arron (Genentech)
GENETIC INSIGHTS AND MODEL DEVELOPMENT TO INVESTIGATE EPITHELIAL CELL SENESCENCE IN IDIOPATHIC PULMONARY FIBROSIS
Saverio Bellusci (University of Giessen)
CHARACTERISATION OF A NOVEL FIBROBLAST GROWTH FACTOR 10 (FGF10)-PRODUCING RESIDENT
Zea Borok (Keck School of Medicine of USC)
ALVEOLAR EPITHELIUM IN PULMONARY FIBROSIS
Wellington Cardoso (Columbia University)
ONTOGENY AND CONTROL OF THE AIRWAY STEM CELL POOL IN DEVELOPMENT AND DISEASE
Gianni Carraro (Cedars-Sinai)
Harold Chapman (University of California, San Francisco)
Elie El Agha (Justus-Liebig-University Giessen)
INTERCONVERSION BETWEEN FIBROBLASTIC PHENOTYPES GOVERNS FIBROSIS FORMATION AND RESOLUTION
John Engelhardt (University of Iowa Carver College of Medicine)
WNT PATHWAY CONTROL OF GLANDULAR MYOEPITHELIAL STEM CELLS IN THE AIRWAY
Finn Hawkins (Boston University)
ORGANOID CULTURES TO MODEL LUNG DEVELOPMENT AND DISEASE
Brigid Hogan (Duke University)
Carla Kim (Boston Children's Hospital)
MICROENVIRONMENTAL REGULATION OF PROGENITOR CELLS IN LUNG HEALTH AND DISEASE
Melanie Koenigshoff (University of Colorado Denver)
Mark Krasnow (Stanford University)
Maya Kumar (Stanford School of Medicine)
Roland Kolbeck (MedImmune)
Susan Majka (Vanderbilt University)
RESIDENT LUNG MESENCHYMAL PROGENITORS MODULATE THE MICROVASCULAR NICHE
Parviz Minoo (Keck School of Medicine of USC)
GENETIC ARCHITECTURE OF ALVEOLAR FORMATION; THE PATH TO DECONVOLUTING PATHOGENESIS OF BRONCHOPULMONARY DYSPLASIA
Edward Morrisey (University of Pennsylvania)
Paul Noble (Cedars-Sinai)
David Ornitz (Washington University)
FGF SIGNALING IN LUNG DEVELOPMENT, CANCER, AND RESPONSE TO INJURY
Anne-Karina Perl (Cincinnati Children's Hospital)
REPROGRAMMING OF THE ALVEOLAR NICHE IN FIBROTIC DISEASE
Jayaraj Rajagopal (Massachusetts General Hospital)
THE AIRWAY EPITHELIAL HIERARCHY REVISITED
Emma Rawlins (University of Cambridge)
CELL-CELL INTERACTIONS IN NORMAL HUMAN LUNG DEVELOPMENT
Jason Rock (Boston University)
MACROPHAGES AND FIBROBLASTS AS NICHES IN THE ADULT LUNG
Jason Spence (University of Michigan)
BASAL CELL DIFFERENTIATION IN THE DEVELOPING HUMAN LUNG
Xin Sun (University of California, San Diego)
SIGNALS IN LUNG DEVELOPMENT AND FUNCTION
Nan Tang (National Institute of Biological Sciences)
THE DRIVING FORCE OF ALVEOLAR DEVELOPMENT, REGENERATION AND DISEASES
Victor Thannickal (University of Alabama at Birmingham)
METABOLIC CONTROL OF CELLULAR PLASTICITY IN LUNG FIBROSIS
David Warburton (Children's Hospital Los Angeles)
EPIGENETIC DNA METHYLATION DEPENDENT CONTROL OF MOUSE LUNG DEVELOPMENT: TEMPORAL AND COMPARTMENTAL SPECIFIC FUNCTIONAL EFFECTS OF INDUCIBLE DNMT1 DELETION IN DEVELOPING MOUSE LUNG MESENCHYME VERSUS EPITHELIUM
Target Audience
- Lung developmental biologists
- Stem cell researchers
- Fibrosis researchers
- Pulmonary fibrosis researchers
Educational Need
It’s is knowns that lung developmental pathways are reactivated in pulmonary fibrosis yet few if any meetings bring lung developmental biologists and researchers studying lung fibrosis together. This meeting will provide a unique opportunity to bring these 2 fields together.
Sponsors
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Media Partners
Prices
All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.
| Early Bird | Full Price |
Additional Adult |
Additional Child |
Extra Night Adult |
Extra Night Child |
|
|---|---|---|---|---|---|---|
| Academic | $1,822.00 | $1,922.00 | $684.00 | $255.00 | $281.00 | $85.00 |
| Industry | $1,822.00 | $1,922.00 | $684.00 | $255.00 | $281.00 | $85.00 |
| Student | $1,533.00 | $1,633.00 | $684.00 | $255.00 | $281.00 | $85.00 |
Additional night prices are per person, per night. Accompanying persons are not permitted access to the conference.
What's Included in our Registration Fees?
Our registration fees are inclusive of the following during the conference period only:
- Conference registration
- 3 Nights’ fixed accommodation (17, 18, 19 Feb 2019) on a single basis for academics and industry, on a shared basis for students
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Gala Dinner (includes an open bar)
- Room service
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in both conference rooms and your guest room
What's Included in our Accompanying Adult Fees?
Our accompanying adult fees are inclusive of the following during the conference period only:
- 3 Nights’ fixed accommodation (17, 18, 19 Feb 2019) on a shared basis with a conference participant
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Gala Dinner (includes an open bar)
- Room service
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in your guest room
Important Note: Accompanying persons are not permitted access to the conference.
What's Included in our Accompanying Child Fees?
Our accompanying child fees are inclusive of the following during the conference period only:
- 3 Nights’ fixed accommodation (17, 18, 19 Feb 2019) on a shared basis with the parent/s
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited bottled water and soft drinks
- Gala Dinner
- Room service
- Non motorized water sports equipment
- Complimentary WIFI in your guest room
Important Note: Accompanying child fees are applicable for children aged 2-12 years. Children younger than 2 years stay free of charge with a parent. Children aged 13 years and older are classified as an adult at this venue (Melia Nassau Beach, Bahamas).
What's Included in our Extra Night Fees?
- 1 night’s accommodation for 1 person
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Room service
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in your guest room
Important Note: Extra night child fees are applicable for children aged 2-12 years.
Speakers
Invited Speakers
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David Ornitz
Washington University -
Susan Majka
Vanderbilt University Medical Center -
Wellington Cardoso
Columbia University Medical Center -
Mark Krasnow
Stanford University School of Medicine -
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Carla Kim
Boston Children's Hospital -
Anne-Karina Perl
Cincinnati Children's Hospital -
Edward Morrisey
University of Pennsylvania -
Saverio Bellusci
Justus-Liebig-Universitaet Giessen, ECCPS -
Hal Chapman
University of California San Francisco -
Xin Sun
UCSD -
Parviz Minoo
University of Southern California and Childrens Hospital -
John Engelhardt
University of Iowa -
David Warburton
Children's Hospital Los Angeles -
Elie El Agha
Justus-Liebig University Giessen -
Brigid Hogan
Duke University -
Jason Rock
Boston University School of Medicine -
Victor Thannickal
University of Alabama at Birmingham -
Nan Tang
National Institute of Biological Sciences, Beijing -
Zea Borok
University of Southern California -
Jay Rajagopal
Massachusetts General Hospital -
Joseph Arron
Genentech -
Jason Spence
University of Michigan -
Roland Kolbeck
MedImmune -
Emma Rawlins
University of Cambridge -
Maya Kumar
Stanford University School of Medicine -
Paul Noble
Cedars-Sinai Medical Center -
Melanie Koenigshoff
CU Denver
Programme
SUNDAY 17TH FEBRUARY 2019 |
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13:15 – 14:00 |
Student & Postdoc Networking Lunch |
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14:00 – 14:50 |
Registration & Welcome Reception |
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Keynote and Emerging Topics session |
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14:50 – 15:00 |
Opening Comments |
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15:00 – 15:30 |
Brigid Hogan |
TBC |
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15:30 – 16:00 |
Paul Noble |
TBC |
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16:00 – 16:30 |
Jayaraj Rajagopal |
THE AIRWAY EPITHELIAL HIERARCHY REVISITED |
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16:30 – 17:00 |
Nan Tang |
THE DRIVING FORCE OF ALVEOLAR DEVELOPMENT, REGENERATION AND DISEASES |
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17:00 – 17:30 |
Refreshments & Poster Viewing |
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Keynote and Emerging Topics session |
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17:30 – 18:00 |
John Engelhardt |
WNT PATHWAY CONTROL OF GLANDULAR MYOEPITHELIAL STEM CELLS IN THE AIRWAY |
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18:00 – 18:30 |
Roland Kolbeck |
TBC |
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18:30 – 18:45 |
Short |
Selected from abstracts |
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18:45 – 19:00 |
Short |
Selected from abstracts |
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19:00 – 19:35 |
Meet the Poster Presenters I |
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19:05 – 19:35 |
Accompanying Guests Pre-Dinner Welcome Drinks |
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19:35 |
Group Dinner |
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MONDAY 18TH FEBRUARY 2019 |
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07:00 – 08:30 |
Buffet Breakfast at The Market Place |
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FGF Signaling in Lung Development and Fibrosis Session (joint session with 3rd Fibroblast Growth Factors in Development and Repair Conference) Session Chair: TBC |
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08:30 – 09:00 |
Mark Krasnow |
TBC |
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09:00 – 09:30 |
Saverio Bellusci |
CHARACTERISATION OF A NOVEL FIBROBLAST GROWTH FACTOR 10 (FGF10)-PRODUCING RESIDENT MESENCHYMAL CELL INVOLVED IN THE REPAIR PROCESS OF THE BRONCHIAL EPITHELIUM AFTER NAPHTHALENE INJURY |
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09:30 – 10:00 |
Stijn De Langhe |
ROLE OF FGF10 SIGNALING IN THE RESOLUTION OF PULMONARY FIBROSIS |
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10:00 – 10:30 |
Xin Sun |
SIGNALS IN LUNG DEVELOPMENT AND FUNCTION |
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10:30 – 11:00 |
Refreshments & Poster Viewing |
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11:00 – 11:30 |
David Ornitz |
FGF SIGNALING IN LUNG DEVELOPMENT, CANCER, AND RESPONSE TO INJURY |
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11:30 – 11:45 |
Short |
TBC |
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11:45 – 12:00 |
Short |
TBC |
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12:00 – 12:15 |
Short |
TBC |
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12:15: 12:30 |
Short |
TBC |
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12:30 – 16:30 |
Lunch at Leisure & Free Time |
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12:30 – 16:00 |
Group Activity: TBC |
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Organoid Cultures to Model Lung Development and Disease Session Session Chair: Xin Sun |
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16:30 – 17:00 |
Jason Spence |
BASAL CELL DIFFERENTIATION IN THE DEVELOPING HUMAN LUNG |
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17:00 – 17:30 |
Carla Kim |
MICROENVIRONMENTAL REGULATION OF PROGENITOR CELLS IN LUNG HEALTH AND DISEASE |
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17:30 – 18:00 |
Emma Rawlins |
CELL-CELL INTERACTIONS IN NORMAL HUMAN LUNG DEVELOPMENT |
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18:00 – 18:30 |
Finn Hawkins |
ORGANOID CULTURES TO MODEL LUNG DEVELOPMENT AND DISEASE |
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18:30 – 19:00 |
Gianni Carraro |
TBC |
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19:00 – 19:15 |
Short Talk |
Selected from abstracts |
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19:15 – 20:30 |
Poster Session & Refreshments |
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20:30 |
Group Dinner |
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TUESDAY 19TH FEBRUARY 2019 |
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07:00 – 08:30 |
Buffet Breakfast at The Market Place |
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Lung Stem/Progenitor Cells and Their Regulation in Health and Disease Session Session Chair: Victor Thannickal |
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08:30 – 09:00 |
Edward Morrisey |
TBC |
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09:00 – 09:30 |
Jason Rock |
MACROPHAGES AND FIBROBLASTS AS NICHES IN THE ADULT LUNG |
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09:30 – 10:00 |
Wellington Cardoso |
ONTOGENY AND CONTROL OF THE AIRWAY STEM CELL POOL IN DEVELOPMENT AND DISEASE |
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10:00 – 10:15 |
Short Talk |
Selected from abstracts |
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10:15 – 10:30 |
Short Talk |
Selected from abstracts |
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10:30 – 11:15 |
Group Photo, Refreshments & Poster Viewing |
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11:15 – 11:45 |
Joseph Arron |
GENETIC INSIGHTS AND MODEL DEVELOPMENT TO INVESTIGATE EPITHELIAL CELL SENESCENCE IN IDIOPATHIC PULMONARY FIBROSIS |
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11:45 – 12:15 |
Invited Speaker Organisation |
TBC |
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12:15 – 12:30 |
Short Talk |
Selected from abstracts |
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12:30 – 12:45 |
Discussion on the future of this Fusion meeting |
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12:45 – 16:30 |
Lunch at Leisure & Free Time |
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Aging and Lung Fibrosis Session Session Chair: Wellington Cardoso |
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16:30 – 17:00 |
Victor Thannickal |
METABOLIC CONTROL OF CELLULAR PLASTICITY IN LUNG FIBROSIS |
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17:00 – 17:30 |
Zea Borok |
ALVEOLAR EPITHELIUM IN PULMONARY FIBROSIS |
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17:30 – 18:00 |
Susan Majka |
RESIDENT LUNG MESENCHYMAL PROGENITORS MODULATE THE MICROVASCULAR NICHE |
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18:00 – 18:45 |
Refreshments & Poster Viewing |
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18:45 – 19:15 |
Harold Chapman |
TBC |
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19:15 – 19:45 |
Melanie Koenigshoff |
TBC |
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19:45 – 20:00 |
Short Talk |
Selected from abstracts |
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20:00 – 20:15 |
Short Talk |
Selected from abstracts |
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20:15 |
*Gala Dinner & Poster Awards* |
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WEDNESDAY 20TH FEBRUARY 2019 |
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07:00 – 08:30 |
Buffet Breakfast at The Market Place |
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Epithelial-Mesenchymal Interactions in Lung Development and Fibrosis Session Session Chair: Saverio Bellusci |
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08:30 – 09:00 |
Maya Kumar |
TBC |
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09:00 – 09:30 |
Anne-Karina Perl |
REPROGRAMMING OF THE ALVEOLAR NICHE IN FIBROTIC DISEASE |
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09:30 – 10:00 |
David Warburton |
EPIGENETIC DNA METHYLATION DEPENDENT CONTROL OF MOUSE LUNG DEVELOPMENT: TEMPORAL AND COMPARTMENTAL SPECIFIC FUNCTIONAL EFFECTS OF INDUCIBLE DNMT1 DELETION IN DEVELOPING MOUSE LUNG MESENCHYME VERSUS EPITHELIUM |
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10:00 – 10:30 |
Parviz Minoo |
GENETIC ARCHITECTURE OF ALVEOLAR FORMATION; THE PATH TO DECONVOLUTING PATHOGENESIS OF BRONCHOPULMONARY DYSPLASIA |
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10:30 – 11:00 |
Refreshments |
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11:00 – 11:30 |
Elie El Agha |
INTERCONVERSION BETWEEN FIBROBLASTIC PHENOTYPES GOVERNS FIBROSIS FORMATION AND RESOLUTION |
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11:30 – 11:45 |
Short Talk |
Selected from abstracts |
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11:45 – 12:00 |
Short Talk |
Selected from abstracts |
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12:00 – 12:15 |
Short Talk |
Selected from abstracts |
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12:15 – 12:30 |
Closing Comments |
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Venue
Melia Nassau Beach All Inclusive
Nassau, Bahamas
W Bay St.
Nassau
Bahamas
Hotel Details
Overlooking one of the finest beaches in the world the Meliá Nassau Beach is surrounded by crystal blue waters and white sandy beaches. Located on the stunning Cable Beach, you are just a few minutes walk from the center, shops and restaurants. The beautiful Nassau Botanical Gardens are within easy reach (7km) and Lynden Pindling International Airport is situated only 9km away.
Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from Cilantro where you can experience the natural textures, aromas and flavors of Mexico, Nikkei, celebrated for its exquisite fusion of Japanese, Cantonese and Peruvian cuisine featuring a sushi bar and Teppanyaki tables, Estavida, an upbeat tapas lounge located in the hotel lobby serving innovative tapas and a wide selection of cocktails, Aqua, an A la carte restaurant specializing in exquisite, rustic Italian cuisine, The Market Place, where you will find an International buffet serving an array of exquisite dishes, O'Grille, an open air restaurant with fabulous views of the sea and pool serving casual beach fare and light bites and finally The Black Angus, a steakhouse featuring hip, contemporary jazz and modern decor, offering guests the finest quality prime cuts and the freshest ingredients.(This restaurant is not included in the all inclusive package, additional charges apply). The Gala Night takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!
Hotel Facilities
- 24 hour reception
- Room service
- 3 heated outdoor pools
- Complimentary resort wide Wi-Fi (guest rooms, throughout hotel, beach and conference areas)
- 24-hour Fitness Center
- 7 dining venues
- 4 bars.
- non-motorised water sports
The Bahamas is formed by over 700 islands, keys and islets located in the Atlantic Ocean and renowned for its warm sunshine, mild climate, fine, white sandy beaches, turquoise, crystal clear water and friendly people, making this the perfect environment to relax and unwind in your free time during the conference.
Location
Melia Nassau Beach All Inclusive
Nassau, Bahamas
Location Details
The Melia Nassau Beach All-Inclusive is located right on the stunning Cable Beach just a few minutes away from the airport and city center; Nearby in Downtown Nassau you can experience the flavours of new foods at local restaurants, shop 'til you drop at Straw market or take a trip through time at the Pirates Museum. The beautiful Nassau Botanical Gardens are close by and water enthusiasts can enjoy non-motorized water sports right on property.
Nassau is the capital of the Bahamas. It lies on the island of New Providence, with neighboring Paradise Island accessible via Nassau Harbor bridges. The city has a hilly landscape and is known for it's fabulous beaches as well as its offshore coral reefs, popular for diving and snorkeling. It retains many of its typical pastel-colored British colonial buildings, like the pink-hued Government House.
Transport
Local Airport
The Melia Nassau Beach Resort is located just 9km from Lynden Pindling International Airport, approximately 10-15 minutes journey time. Formerly known as Nassau International Airport, it is the largest airport in the Bahamas and provides an international gateway into the country.
We will be partnering with a local reputable company that will provide transportation services for our attendees. Further information will be available nearer the time.
Activities
Several activities are available within the resort and include:
- Sports: Volleyball / basketball
- Fitness classes
- Snorkeling
- Kayaking
Further tours and excursion information will be available shortly.
Group Activities
To be announced.
Oral Presenters
Talk Deadline: 02 Nov 2018
We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.
Your Presentation
On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.
Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.
We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.
Please make sure your presentation adheres to the following guidelines.
Aspect Ratio: On Screen Show 16:9 (we can also accommodate 4:3 presentations)
File Type: Please save your presentation in PPT, PPTS or Keynote format
Posters
Poster Deadline: 03 Dec 2018
We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.
Displaying & Presenting Your Poster
Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you.
Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.
Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.
Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.