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3rd DNA Replication/Repair Structures and Cancer Conference

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Registration Deadlines

Early bird – 18 Aug 2017

Talk Submission – 08 Sep 2017

Poster Submission – 17 Nov 2017

Last Chance – 01 Dec 2017

Past Conference

3rd DNA Replication/Repair Structures and Cancer Conference

11 Feb 2018 - 15 Feb 2018

Cancun, Mexico

Synopsis

The remarkable stability of the human genome is lost in cancer cells due to the failure of efficient and accurate repair in the context of oncogene-induced replication stress and elevated transcription. DNA replication is furthermore emerging as a surprisingly fragile and complex process requiring fork protection and restart, template-switching, R-loop resolution, gap-filling, and repair. Unresolved replication and repair intermediates signal apoptosis. The synthetic lethality and essentiality resulting from replication-repair stresses thus suggest repair inhibitors as tools to control pathway selection and damage outcomes and to design advanced therapeutics.

The 3rd DNA Replication/Repair Structures & Cancer conference in February 2018 will focus on structural and mechanistic insights into dynamic protein, chromatin, DNA and RNA complexes acting in DNA replication and repair events relevant to cancer. Conference talks and discussions will center on developing an actionable mechanistic knowledge of DNA replication and repair stress responses suitable to guide advanced intervention strategies for cancer. The conference will emphasize an environment suitable for initiating productive collaborations. It will include vibrant informal and formal discussions together with informative talks and poster sessions.

To include late-breaking advances and innovating new investigators, one or more talks for every session will be selected from submitted abstracts. Meeting attendance is limited. Applicants seeking to present talks or posters are strongly encouraged to submit applications and abstracts early. All presenters are asked to focus on unpublished work, cutting-edge approaches and novel mechanistic insights that aid prediction of biological outcomes and plans to best apply basic research advances for cancer research and treatment.

What makes this meeting unique? Professor Ben Van Houten from the University of Pittsburgh says:

‘I can honestly say your meeting, by combining hard core structure-function studies with beautiful biology, hits an important area that many meetings miss; being part of that science is just terrific.’

Key Sessions

Sessions will include emerging results and breakthrough methods concerning:

  • Repair and replication complexes, structures and mechanisms
  • Mutational signatures, kataegis, DNA repair, and cancer
  • Damage signaling, pathway selection & cross-talk
  • Targeting synthetic lethality and essentiality for damage responses
  • Chromatin and chromosome instability
  • Epigenetics, DNA damage and repair
  • PARP, PARG, and metabolic signaling
  • Mitochondrial replication/repair and damage signaling
  • RNA damage responses and actions in repair
  • DNA repair, apoptosis and cancer

Confirmed Keynote Speakers

Steve Jackson (University of Cambridge)
Bruce Stillman (CSHL)
Steve West (The Francis Crick Institute)
Serena Nik-Zainal (Wellcome Trust Sanger Institute)

Confirmed Invited Speakers

Lorena Beese (Duke University Medical Center)
Simon Boulton (The Francis Crick Institute)
Chris Brosey (MD Anderson Cancer Center)
Jean-Baptiste Charbonnier (University Paris‐Saclay)
Walter Chazin (Vanderbilt University)
David Cortez (Vanderbilt University)
Sheila David (University of California, Davis)
Sylvie Doublié (University of Vermont)
Jessica Downs (Institute of Cancer Research)
Brandt Eichman (Vanderbilt University)
Dorothy Erie (University of North Carolina)
Ilya Finkelstein (University of Texas at Austin)
Marco Foiani (University of Milan)
Mark Glover (University of Alberta)
Jane Grasby (Krebs Institute)
Jim Haber (Brandeis University)
Samir Hamdan (KAUST)
Reuben Harris (University of Minnesota)
Ben Van Houten (University of Pittsburgh)
Meindert Lamers (MRC Laboratory of Molecular Biology)
Susan Lees-Miller (Arnie Charbonneau Cancer Institute)
Karolin Luger (University of Colorado at Boulder)
Mauro Modesti (Cancer Research Center of Marseille)
Zachary Nagel (Harvard University)
Mark O'Connor (AstraZeneca)
John Pascal (Université de Montréal)
Tanya Paull (University of Texas at Austin)
Luca Pellegrini (University of Cambridge)
Phoebe Rice (University of Chicago)
Andrej Sali (University of California, San Francisco)
Titia Sixma (NKI)
Orlando Scharer (Ulsan National Institute of Science and Technology)
Katharina Schlacher (MD Anderson Cancer Center)
Maria Spies (University of Iowa)
Madalena Tarsounas (The CR-UK/MRC Oxford Institute for Radiation Oncology)
Susan Tsutakawa (Lawrence Berkeley National Laboratory)
Ashok Venkitaraman (University of Cambridge)
Keith Wilcoxen (Tesarobio)
Scott Williams (NIEHS)
Wei Yang (NIH)

Prices

All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.

Early Bird Full
Price
Additional
Adult
Additional
Child
Extra Night
Adult
Extra Night
Child
Academic $1,779.00 $1,854.00 $809.00 $355.00 $292.00 $71.00
Industry $1,779.00 $1,854.00 $809.00 $355.00 $292.00 $71.00
Student $1,451.00 $1,526.00 $809.00 $355.00 $292.00 $71.00

Additional night prices are per person, per night. Accompanying persons are not permitted access to the conference.

What's Included in our Registration Fees?

Our registration fees are inclusive of the following during the conference period only:

- Conference registration.
- 4 nights’ fixed accommodation (11, 12, 13 and 14 February 2018) on a single basis for academics and industry, on a shared basis for students.
- Breakfast, Lunch and Dinner – available at all restaurants according to operational hours or programmed events.
- International Bar available by the glass in restaurants and bars according to operational hours.
- Pool snacks and International Bar available by the glass at pool area.
- Minibar including: soft drinks, domestic beer, bottled water and coffee. Refreshed daily.
- 24 Hour Room Service.
- In room amenity – bottle of wine, per room, per stay.
- Gala Night entry (includes an open bar).
- Complimentary WIFI in both conference rooms and your guest room.

What's Included in our Accompanying Adult Fees?

Our accompanying adult fees are inclusive of the following during the conference period only:

- 4 nights’ fixed accommodation (11, 12, 13 and 14 February 2018) on a shared basis with a conference participant.
- Breakfast, Lunch and Dinner – available at all restaurants according to operational hours or programmed events.
- International Bar available by the glass in restaurants and bars according to operational hours.
- Pool snacks and International Bar available by the glass at pool area.
- Minibar including: soft drinks, domestic beer, bottled water and coffee. Refreshed daily.
- 24 Hour Room Service.
- In room amenity – bottle of wine, per room, per stay.
- Gala Night entry (includes an open bar).
- Complimentary WIFI in both conference rooms and your guest room.

Important Note: Accompanying persons are not permitted access to the conference.

What's Included in our Accompanying Child Fees?

Our accompanying child fees are inclusive of the following during the conference period only:

- 4 nights’ fixed accommodation (11, 12, 13 and 14 February 2018) on a shared basis with the parent/s.
- Breakfast, Lunch and Dinner – available at all restaurants according to operational hours or programmed events.
- International Bar available by the glass in restaurants and bars according to operational hours.
- Pool snacks and International Bar available by the glass at pool area.
- Minibar including: soft drinks, bottled water and coffee. Refreshed daily.
- 24 hour room service.
- Gala Night entry (includes soft drinks).
- Complimentary WIFI in both conference rooms and your guest room. 

Important Note: Accompanying child fees are applicable for children aged 5-12 years. Children aged 0-4 years stay free of charge with a parent. Children aged 13 years and older are classified as an adult at this venue (Fiesta Americana Condesa). Roll out beds are available upon request but can only be guaranteed at the point of check-in.

What's Included in our Extra Night Fees?

Additional nights are inclusive of one night’s accommodation and the all-inclusive food and beverage package.

Important Note: Extra night child fees are applicable for children aged 5-12 years.

Speakers

No Speaker information available

Programme

Although the programme has not yet been released, we are able to confirm that the conference should begin no earlier than 16:00 with opening comments on 11 February 2018. The conference will conclude no later than 12:30 on 15 February 2018.

Sponsors

No Sponsors info available

Sponsor this conference

Venue

Fiesta Americana Condesa

Cancun, Mexico

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Venue Rating
5 Stars
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa,
Blvd.Kukulkán km 16.5 Zona Hotelera,
Cancun,
77500
Mexico
Nearest Airport
Cancun International Airport

Hotel Details

This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment.  We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

  • Lagoon Pool
  • Extensive Health Club and Spa
  • Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas

The Fiesta Americana Condesa, Cancun is the 2015 Winner of the Trip Advisor Certificate of Excellence and also received the Travellers Choice Award in 2014. 

The remains of ancient Mayan cities are scattered throughout the Yucatan Peninsula and no trip to Cancun would be complete without a visit to these majestic temples and pyramids set amongst lush tropical vegetation. We will be working very closely with a reputable tour company who will be organising trips to Tulum, Chichen Itza, Coba and Xcaret to name a few, some of which may require a full day. Full day excursions will be arranged pre or post conference and may be on an individual or group booking so we would recommend booking extra nights to extend your stay as early as possible to avoid disappointment should these excursions be of interest to you and/or your party. For further information please contact us.

Location

Fiesta Americana Condesa

Cancun, Mexico

Venue Rating
5 Stars
Currency
US Dollar (USD)
Nearest Airport
Cancun International Airport

Location Details

Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.

Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.

Transport

Details will be available at a later date.

Activities

Details will be available at a later date.

Group Activities

Details will be available at a later date.

Oral Presenters

Talk Deadline: 08 Sep 2017

We have a number of oral opportunities available at this meeting. To be considered for a talk, please register for the conference and you will be able to submit your abstract online and monitor the status of your abstract through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Please take note of the oral submission deadline: 25 September 2017.

Please check the conference programme carefully to note your presentation time (inclusive of Q&A) should you be accepted for an oral presentation. We recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference page.

Your Presentation on the Day

If you have prepared some slides to accompany your talk please ensure you bring these with you on a USB or portable file saving device.

For those presenting on the first day, please email your slides to us so we can have everything prepared and ready for the first session. Please email your slides to: admin@fusion-conferences.com

On the day of your presentation please make yourself known to the AV team who will be available in the conference room. If you have any animations or videos we do advise to run through the presentation with the AV tech to make sure everything is compatible. We also advise that all speakers make themselves known to the AV tech in the conference room immediately before your session beings. The AV tech will apply your microphone and provide a laser pointer should you have an accompanying presentation. We prefer speakers to use our master laptop to run presentations from, however, if you prefer to use your own laptop, please notify us in advance.

It is important that all speakers adhere to their presentation time and respect their fellow presenters. A visual traffic light aide will be available to warn presenters and the audience as your time decreases.

If you have any questions, please don’t hesitate to approach our AV tech or a member of the Fusion team.

Helpful Tips for Presentation Slides

Aspect Ratio: 4:3 in Presenter View, Landscape in Orientation
Font Size: Minimum font size used should be 24pt. 
File Type: Please save your presentation in PPT or PPTS format. 
Video Clips: Please save these separately and do not build them into the PowerPoint. Videos will be played via the AV control desk using the master laptop.

Download Template

Posters

Poster Deadline: 17 Nov 2017

We have a number of poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and you will be able to submit your abstract online and monitor the status of your abstract through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Please take note of the poster submission deadline: 01 December 2017.

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

During conference registration if you are presenting a poster please request a poster number from the registration desk. Please do not put up your poster without notifying a member of the Fusion team. Certain adhesive agents are not permitted at some venues therefore; Fusion will be the sole provider of all poster fixings.

You can display your poster from registration. Your poster can remain on display for the entire duration of the conference and we ask that posters are taken down on the final day of the meeting. The poster session is usually scheduled on Day 3, but please check the official programme for exact timings. Refreshments will be provided and the poster prizes will be awarded during the conference Gala Night that evening. 

2018 DRRSC Poster Prize

The conference chairs will be awarding 3 poster prizes for the best poster display and presentation. To be in with a chance of winning, submit your poster by 01 December 2017. The winners will be selected shortly after the Poster Session and the following prizes will be awarded: 1st Place $350, 2nd Place $250, 3rd Place $150.

Download Template