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Last Chance – 16 Jan 2018

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Nuclear Receptors Conference

New Roles for Nuclear Receptors in Development, Health and Disease

27 Feb 2018 - 02 Mar 2018

Cancun, Mexico

Synopsis

Nuclear Receptors are, physiologically and pharmacologically, a critical superfamily of transcription factors. They drive key processes at every stage from development and reproduction to ageing and cancer. They are critical determinants of everyday health via their roles in metabolism and circadian rhythms. Nuclear receptors allow external factors to influence cellular pathways and the fact that many bind and are activated by small molecules means they represent highly druggable targets; currently, 13% of FDA-approved drugs target nuclear receptors.

This meeting will address the new roles and novel crosstalk mechanisms that are emerging for many of the 48 human nuclear receptors, in health and disease. For example, it has long been known that the estrogen receptor drives progression of breast cancer, and patients with estrogen receptor-positive disease are treated using antiestrogens or aromatase inhibitors to inhibit estrogen signalling. Now however, it is apparent that the androgen receptor can in some cases drive breast cancer progression and is a therapeutic target, resulting in clinical trials for androgen receptor-targeting therapies in advanced breast cancer. The androgen receptor, itself long the main therapeutic target in prostate cancer, is emerging as a key player in metabolic disease, while conversely other nuclear receptor including the glucocorticoid receptor and several orphan nuclear receptors are implicated in prostate cancer progression. Meanwhile, given the impact of many nuclear receptors on the central nervous system, it is unsurprising that they are being explored in the context of neurological disorders and depression. Thus there is wide scope for re-purposing of licensed drugs and development of new NR-targeting therapies for a host of conditions and diseases.

Crosstalk between nuclear receptors and other fundamental processes is another exciting expanding area that will also be covered. DNA damage repair pathways are inextricably linked to steroid signalling via transcriptional processes, with implications for drug combinations in several diseases. Hitherto unsuspected roles of nuclear receptors in epigenetic control and the processing and function of non-coding RNAs opens up to capacity of this superfamily to further means of impacting on development and normal functioning, but also on disease development. 

This unique meeting will bring together many of the leading figures in nuclear receptor research from across the globe, to discuss emerging roles and their implications for health and disease – and both human and drug development – in an intimate meeting that will generate meaningful idea exchange and interaction that will help to further shape this influential field.

Join the conference LinkedIn group to keep up to date with announcements and latest news concerning the conference.

Key Sessions

  • Further emerging roles for nuclear receptors in cancer
  • Structural insights into nuclear receptor function and crosstalk
  • Nuclear receptors’ role in epigenetic regulation and non coding RNA
  • Nuclear receptors and DNA damage
  • Nuclear receptors and cell cycle
  • Nuclear receptors in metabolism/metabolic disease
  • Nuclear receptors in the CNS

Target Audience

Scientists and Clinician Scientists at a range of levels from postdoctoral and up: Principal Investigators, Junior Team Leaders, Research Fellows. Ambitious postgraduate students in the field will also be encouraged to attend.

Relevant specialties are wide-ranging, reflecting the importance of nuclear receptors in many aspects of health and disease. These include Endocrinology, Oncology, Paediatrics, Urology, Gynaecology, Obstetric Medicine, Neuroscience, Cardiology.

Learning Objectives 

  1. Introduce the newest advances, in discovery and methodology in the field of Nuclear Receptor research to a wide audience, through oral and poster presentation with both formal and informal discussion.
  2. Develop a deeper understanding of the latest advances in our knowledge of nuclear receptor biology at all levels (structural, transcriptional, cross-talk with each other and with different pathways) and the subsequent effects on development, reproduction and disease.
  3. Consider and possibly extend the evidence base for re-purposing of nuclear receptor-targeting therapies
  4. Provide an environment for cross-talk and cross-fertilisation between all Nuclear Receptor-related disciplines (reproduction, fertility, neuroscience, oncology, structural biology, transcription) allowing the different disciplines to learn from each other and forge new collaborations
  5. Celebrate over 30 years of Nuclear Receptor research while discussing the next challenges in the field and how we can address them.

Student Grants

We currently have 3 x $800 student grants available for the conference to help offset the cost of registration. If this is of interest to you, please send the following to Meredith@fusion-conferences.com by 15th January 2018

  • Name and brief description of your current research
  • Why you would benefit from attend
  • An abstract for poster consideration

Student Offer

Take advantage of this fantastic opportunity for students! Register an academic at the standard rate of $1,798.00 and bring a student for only $745. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 27th February, 28th February and 1st March 2018 (on a shared basis for students, note guest rooms are open plan) and a 24hour all-inclusive food and beverage package for the conference period. Once you have registered and paid in full, please contact Meredith Willmott (Meredith@fusion-conferences.com) to obtain a special registration link for your student.

Publishing Opportunity

We are delighted to be working with Bioscientifica publishing house to publish abstracts from the Nuclear Receptors Conference, 27th February – 02nd March 2018 in Cancun, Mexico. Bioscientifica publishes many of the leading journals and online products in endocrinology on behalf of, and in collaboration with, key endocrine societies worldwide. They provide permanent, citable, free-to-read records of meeting abstracts, ensuring the content from an event remains discoverable and available in perpetuity, prolonging the life of the event.

If consent is given abstracts from speakers, oral presenters and poster presenters will be published. Please see the Bioscientifica website for more information about them.

If you would like your abstract to be published, please provide consent by confirming via email (meredith@fusion-conferences.com). Please note this opportunity is not mandatory we will only publish abstracts if consent has been given. 

Confirmed Plenary Speakers

Geoffrey Greene (The University of Chicago)
UNDERSTANDING AND EXPLOITING STEROID RECEPTOR CROSS TALK IN HORMONE SENSITIVE CANCERS

Bert O'Malley (Baylor College of Medicine)
NUCLEAR RECEPTORS AND THEIR COACTIVATORS: AN ENTRE TO UNDERSTANDING HUMAN DISEASES

David Moore (Baylor College of Medicine)

Confirmed Invited Speakers

Suzanne Conzen (The University of Chicago)
MODULATING GLUCOCORTICOID RECEPTOR FUNCTION IN BREAST AND PROSTATE CANCER

Frank Claessens (University of Leuven)
DIRECT AND INDIRECT EFFECTS OF ANDROGENS ON THE MUSCULOSKELETAL SYSTEM

Scott Dehm (University of Minnesota)
CLINICALLY-RELEVANT CONTEXTS FOR AR VARIANTS IN PROSTATE CANCER

Theresa Hickey (The University of Adelaide)

Lee Kraus (The University of Texas Southwestern Medical Center)
NUCLEAR RECEPTORS, TRANSCRIPTIONAL ENHANCERS, AND GENE REGULATION

Luca Magnani (Imperial College London)
MAPPING THE EPIGENOME OF BREAST CANCER PATIENTS TO EXPOSE NEW MECHANISMS OF ENDOCRINE THERAPY RESISTANCE

Susanne Mandrup (University of Southern Denmark)
TRANSCRIPTIONAL NETWORKS REGULATING MSC DIFFERENTIATION

Sebastiaan Meijsing (Max Planck Institute for Molecular Genetics)
TRANSCRIPTIONAL REGULATION BY THE GLUCOCORTICOID RECEPTOR: ROLE OF DNA SHAPE AND SEQUENCE IN MODULATING OUTPUT AND NOISE

Eric Ortlund (Emory University)
TARGETING LRH-1 WITH SMALL MOLECULE MODULATORS

Steffi Oesterreich (Women's Cancer Research Institute)

Eva Estébanez-Perpiñá (University of Barcelona)
ANDROGEN RECEPTOR DIMERIZATION

David Ray (The University of Manchester)
RAPID, CYTOPLASMIC ACTIONS OF THE GLUCOCORTICOID RECEPTOR IMPACT ON CELL MOVEMENT

Ganesh Raj (University of Texas Southwestern Medical Center)

Yijun Ruan (The Jackson Laboratory)

Philippa Saunders (University of Edinburgh)
ANDROGENS AND ENDOMETRIAL FUNCTION: REPLICATION, REPAIR AND REGENERATION

Carol Sartorius (University of Colorado)
PROGESTERONE RECEPTOR REGULATION OF CANCER CELL TRANSLATION

John Schwabe (University of Leicester) 

Carlie de Vries (University of Amsterdam)
NUR77 GOES METABOLIC IN MACROPHAGES

Catherine Williamson (King's College London)
GESTATIONAL METABOLIC ADAPTATIONS SIGNALLED THROUGH NUCLEAR RECEPTORS

Wilbert Zwart (Netherlands Cancer Institute)
ESTROGEN RECEPTOR CISTROMICS IN BREAST TUMORS: FROM BIOMARKERS TO NOVEL DRUG TARGETS




Sponsors

Prices

All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.

Early Bird Full
Price
Additional
Adult
Additional
Child
Extra Night
Adult
Extra Night
Child
Academic $1,748.00 $1,798.00 $626.00 $284.00 $292.00 $71.00
Industry $1,748.00 $1,798.00 $626.00 $284.00 $292.00 $71.00
Student $1,490.00 $1,540.00 $626.00 $284.00 $292.00 $71.00

Additional night prices are per person, per night. Accompanying persons are not permitted access to the conference.

Accompanying child fees and extra night child fees are applicable for children aged 5-12 years of age. Children aged 13 years and older are classified as an adult at this venue (Fiesta Americana Condesa). 

What's Included in our Registration Fees?

The Fiesta Americana Condesa, Cancun offers a 24hour all inclusive service. Our registration and additional adult/child fees are inclusive of the following;

- Accommodation for 3 Nights (27th February, 28th February and 1st March 2018).
- Breakfast, Lunch and Dinner – available at all restaurants according to operational hours or programmed events.
- International Bar available by the glass in restaurants and bars according to operational hours.
- Pool snacks and International Bar available by the glass at Pool Area.
- Minibar including: soft drinks, domestic beer, bottled water and coffee. Refreshed daily.
- 24 Hour Room Service.
- In Room amenity – Bottle of wine, per room, per stay.
- Gala Night Entry (includes an open bar).
- Complimentary WI-FI throughout the hotel.

Additional nights (per person) are inclusive of the following;

- Accommodation for 1 Night
- Lunch on day of arrival
- Dinner on day of arrival
- Breakfast on day of departure
- International bar available by the glass in restaurants and bars from lunch on day of arrival until breakfast on day of departure

Speakers

Plenary Speakers

Invited Speakers

  • Sebastiaan Meijsing
    Sebastiaan Meijsing
    Max Planck Institute for Molecular Genetics
  • Carlie de Vries
    Carlie de Vries
    Academic Medical Center, Uni of Amsterdam
  • Theresa Hickey
    Theresa Hickey
    University of Adelaide
  • W. Lee Kraus
    W. Lee Kraus
    Ut Southwestern Medical Center
  • Luca  Magnani
    Luca Magnani
    Imperial College London
  • Philippa Saunders
    Philippa Saunders
    The University of Edinburgh
  • Susanne Mandrup
    Susanne Mandrup
    University of Southern Denmark
  • Frank Claessens
    Frank Claessens
    KU Leuven
  • David Ray
    David Ray
    University of Manchester
  • Steffi  Oesterreich
    Steffi Oesterreich
    Women's Cancer Research Institute
  • Carol Sartorius
    Carol Sartorius
    University of Colorado Anschutz Medical Campus
  • Wilbert Zwart
    Wilbert Zwart
    Netherlands Cancer Institute
  • Eric Ortlund
    Eric Ortlund
    Emory University
  • Ganesh Raj
    Ganesh Raj
    UT Southwestern Medical Center
  • Gordon Hager
    Gordon Hager
    National Cancer Inst, NIH
  • Scott Dehm
    Scott Dehm
    Masonic Cancer Center, University of Minnesota
  • Charlotte Cornil
    Charlotte Cornil
    Univeristy of Liege
  • Yijun Ruan
    Yijun Ruan
    The Jackson Laboratory
  • Suzanne Conzen
    Suzanne Conzen
    The University of Chicago
  • David VOLLE
    David VOLLE
    CNRS UMR 6293, Inserm U1103, UCA
  • Catherine Williamson
    Catherine Williamson
    King's College London
  • Eva Estebanez-Perpina
    Eva Estebanez-Perpina
    University of Barcelona
  • John Schwabe
    John Schwabe
    University of Leicester

Programme

TUESDAY 27th FEBRUARY 2018

14:00 – 14:45

Registration & Reception

14:00 – 14:45

Group Welcome Lunch

Session Title:  NR in Development, Metabolism and Reproduction
Session Chair Name: TBC

14:45 – 15:00

Opening Comments

15:00 – 15:45

David Moore
Baylor College of Medicine

REGULATION OF LIVER ENERGY BALANCE BY PPARALPHA AND FXR

15:45 – 16:15

Carlie de Vries
University of Amsterdam

NUR77 GOES METABOLIC IN MACROPHAGES

16:15 – 16:45

Frank Claessens
University of Leuven

DIRECT AND INDIRECT EFFECTS OF ANDROGENS ON THE MUSCULOSKELETAL SYSTEM

16:45 – 17:15

Charlotte Cornil
University of Liege

ESTROGEN NUCLEAR- AND MEMBRANE-INITIATED SIGNALING COOPERATE TO REGULATE BEHAVIOR

17:15 – 17:45

Refreshments

17:45 – 18:15

David Volle
Université Clermont Auvergne

TBC

18:15 – 18:45

Catherine Williamson
King's College London

GESTATIONAL METABOLIC ADAPTATIONS SIGNALLED THROUGH NUCLEAR RECEPTORS

18:45 – 19:00

Kendall Nettles
The Scripps Research Institute 

CHEMICAL SYSTEMS BIOLOGY ANALYSES REVEAL DISSOCIATED GLUCOCORTICOID SIGNALING NETWORKS IN SKELETAL MUSCLE

19:00 – 19:30

PM Panel Discussion

19:30

Dinner at Leisure

WEDNESDAY 28th FEBRUARY 2018

07:00 – 08:30

Breakfast

Session Title: NR-NR Crosstalk

Session Chair Name: TBC

08:30 – 09:15

Karen Knudsen
Thomas Jefferson University

 DNA REPAIR-ANDROGEN INTERPLAY IN PROSTATE CANCER

09:15 – 09:30

Amit Dash
Jawaharlal Nehru University

HETERODIMERIZATION OF RETINOID X RECEPTOR WITH XENOBIOTIC NUCLEAR RECEPTORS OCCURS IN THE CYTOPLASMIC COMPARTMENT OF CELL IN A LIGAND INDEPENDENT MANNER

09:30 – 10:00

Theresa Hickey
The University of Adelaide

TBC

10:00 – 10:30

Refreshments

10:30 – 11:00

Wilbert Zwart
Netherlands Cancer Institute

ESTROGEN RECEPTOR CISTROMICS IN BREAST TUMORS: FROM BIOMARKERS TO NOVEL DRUG TARGETS

11:00 – 11:30

Suzanne Conzen
The University of Chicago

MODULATING GLUCOCORTICOID RECEPTOR FUNCTION IN BREAST AND PROSTATE CANCER

11:30 – 12:00

AM Panel Discussion

12:00 – 16:00

Lunch at Leisure & Free Time

12:40 – 15:45

Group Trip: Snorkeling (signups required in advance)

Session Title:  Epigenetics & Chromatin Regulation
Session Chair Name: TBC

16:00 – 16:30

Lee Kraus
UT Southwestern Medical Center

NUCLEAR RECEPTORS, TRANSCRIPTIONAL ENHANCERS, AND GENE REGULATION

16:30 – 17:00

Luca Magnani
Imperial College London

 MAPPING THE EPIGENOME OF BREAST CANCER PATIENTS TO EXPOSE NEW MECHANISMS OF ENDOCRINE THERAPY RESISTANCE

17:00 – 17:30

Charlotte Bevan
Imperial College London

MICRORNA REGULATION OF ANDROGEN SIGNALLING

17:30 – 18:00

Yijun Ruan
The Jackson Laboratory

TBC

18:00 – 18:30

Refreshments

18:30 – 19:00

Carol Sartorius
University of Colorado

PROGESTERONE RECEPTOR REGULATION OF CANCER CELL TRANSLATION

19:00 – 20:00

Bert O'Malley
Baylor College of Medicine

NUCLEAR RECEPTORS AND THEIR COACTIVATORS: AN ENTRE TO UNDERSTANDING HUMAN DISEASES

20:00 – 20:30

PM Panel Discussion

20:30

Dinner at Leisure

THURSDAY 1st MARCH 2018

07:00 – 08:30

Breakfast

Session Title: NR in cancer
Session Chair Name: TBC

08:30 – 09:00

Gordon Hager
National Cancer Institute

TBC

09:00 – 09:15

Moray Campbell
The Ohio State University

STAGE-SPECIFIC AND GLOBAL FUNCTIONS OF NCOR2 IN PROSTATE CANCER PROGRESSION

09:15 – 09:45

Scott Dehm
University of Minnesota

CLINICALLY-RELEVANT CONTEXTS FOR AR VARIANTS IN PROSTATE CANCER

09:45 – 10:15

Steffi Oesterreich
University of Pittsburgh

TBC

10:15 – 10:45

Refreshments

10:45 – 11:15

Ganesh Raj
UT Southwestern Medical Center

TBC

11:15 – 11:30

Amina Zoubeidi
University of British Columbia

RATIONALE TARGETING CELL PLASTICITY IN TREATMENT RESISTANT PROSTATE CANCER

11:30 – 12:00

John Schwabe
University of Leicester

TBC

12:00 – 12:30

Antonio Moschetta
University of Bari Aldo Moro

TBC

12:30 – 13:15

AM Panel Discussion

13:15 – 16:00

Lunch at Leisure & Free Time

Session Title:  NR in non-malignant disorders  

Session Chair Name: TBC

16:00 – 16:30

Philippa Saunders
The University of Edinburgh

ANDROGENS AND ENDOMETRIAL FUNCTION: REPLICATION, REPAIR AND REGENERATION

16:30 – 16:45

Pamela England
University of California, San Francisco

DE-ORPHANING AND DRUGGING NURR1 – A THERAPEUTIC TARGET FOR PARKINSON’S DISESASE

16:45 – 17:15

David Ray
The University of Manchester

RAPID, CYTOPLASMIC ACTIONS OF THE GLUCOCORTICOID RECEPTOR IMPACT ON CELL MOVEMENT

17:15 – 17:30

Sang Jun Han
Baylor College of Medicine

THE PATHOGENIC ROLE OF ESTROGEN RECEPTOR ΒETA DRIVES IN ENDOMETRIOSIS

17:30 – 18:00

Susanne Mandrup
University of Southern Denmark

TRANSCRIPTIONAL NETWORKS CONTROLING MESENCHYMAL STEM CELL DIFFERENTIATION

18:00 – 18:15

Toshiya Tanaka 
The University of Tokyo

PEMAFIBRATE, A SELECTIVE PPARΑ MODULATOR (SPPARMΑ), PREVENTS INTRAHEPATIC MACROPHAGE ACCUMULATION AND ACTIVATION OF NON-ALCOHOLIC STEATOHEPATITIS

18:15 – 18:30

Ines Pineda-Torra
University College London

BEYOND LIGAND ACTIVATION: DISRUPTING LXRΑ PHOSPHORYLATION TO REPROGRAM DIETINDUCEDTRANSCRIPTOMES AND MODULATE PROGRESSION OF METABOLIC DISEASES

18:30 – 19:00

PM Panel Discussion

19:00 – 20:00

Poster Session & Refreshments

20:00

*Gala Dinner & Poster Awards*

 

FRIDAY 2nd MARCH 2018

07:00 – 08:30

Breakfast

Session Title:  NR structure & regulation
Session Chair Name: TBC

08:30 – 09:15

Geoffrey Greene
The University of Chicago

UNDERSTANDING AND EXPLOITING STEROID RECEPTOR CROSS TALK IN HORMONE SENSITIVE CANCERS

09:15 – 09:45

Eva Estébanez-Perpiñá
University of Barcelona

ANDROGEN RECEPTOR DIMERIZATION

09:45 – 10:15

Eric Ortlund
Emory University 

TARGETING LRH-1 WITH SMALL MOLECULE MODULATORS

10:15 – 10:45

Sebastiaan H. Meijsing
Max Planck Institute for Molecular Genetics

TRANSCRIPTIONAL REGULATION BY THE GLUCOCORTICOID RECEPTOR: ROLE OF DNA SHAPE AND SEQUENCE IN MODULATING OUTPUT AND NOISE

10:45 – 11:15

Refreshments

11:15 – 11:30

Eric Kalkhoven
Utrecht University

NATURAL PPARγ MUTANTS: A MODEL FOR ALLOSTERIC SIGNALING BETWEEN NUCLEAR RECEPTORS AND DNA

11:30 – 11:45

Sylvie Mader
Université de Montréal

ROLE OF CHROMATIN REMODELING IN THE SUPPRESSION OF ESTROGEN-INDUCED TRANSCRIPTION BY PURE ANTIESTROGENS

11:45 – 12:15

AM Panel Discussion

12:15 – 12:30

Closing Comments

13:00 – 19:50

Group Trip: Tulum 

 

 

 

Sponsors

Sponsor this conference

Venue

Fiesta Americana Condesa

Cancun, Mexico

Fiesta Americana Condesa Fiesta Americana Condesa Fiesta Americana Condesa Fiesta Americana Condesa Fiesta Americana Condesa

Venue Rating
5 Stars
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa,
Blvd.Kukulkán km 16.5 Zona Hotelera,
Cancun,
77500
Mexico
Nearest Airport
Cancun International Airport

Hotel Details

This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment.  We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

  • Lagoon Pool
  • Extensive Health Club and Spa
  • Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas

The Fiesta Americana Condesa, Cancun is the 2015 Winner of the Trip Advisor Certificate of Excellence and also received the Travellers Choice Award in 2014. 

The remains of ancient Mayan cities are scattered throughout the Yucatan Peninsula and no trip to Cancun would be complete without a visit to these majestic temples and pyramids set amongst lush tropical vegetation. We will be working very closely with a reputable tour company who will be organising trips to Tulum, Chichen Itza, Coba and Xcaret to name a few, some of which may require a full day. Full day excursions will be arranged pre or post conference and may be on an individual or group booking so we would recommend booking extra nights to extend your stay as early as possible to avoid disappointment should these excursions be of interest to you and/or your party. For further information please contact us.

Location

Fiesta Americana Condesa

Cancun, Mexico

Venue Rating
5 Stars
Currency
US Dollar (USD)
Nearest Airport
Cancun International Airport

Location Details

Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.

Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.

Transport

 

 

Activities

Details will be available at a later date.

Group Activities

 

We have arranged three exciting group activities for the 2018 Nuclear Receptors participants. This is a great opportunity to socialise with fellow colleagues outside of the conference whilst taking in the beautiful natural sights of Mexico. Please find details, timings and prices for the activities below. The activities are either scheduled pre or post conference, or during free time between sessions. Please carefully check the date and timings of each activity before signing up.

Snorkel Trip-  Wednesday 28th February 2018

Departing from Aquaworld marina we take you on a motor boat to Punta Nizuc reef area where you disembark to the floating platform. Here you adorn your snorkel gear and you’re ready to take the plunge and snorkel as long as you like in the crystal clear turquoise waters.

Price: $57.00 per person
Price: $36.00 per person (child 4-10 years)
*please note prices do not include gratuity.

Includes:

-Travel through the lagoon and mangrove channels
-Snorkel guided tours
-Full snorkel equipment with a new tube as a gift
-Beer, sodas and bottled water
-Docking fee

Itinerary for Wednesday 28th February 2018:

Walk to Aquaworld from hotel- 10/15 minutes (across the road from the hotel)
12:30 Walk to Aquaworld Marina from hotel
13:00 Boat trip from Aquaworld Marina
13:45 Snorkelling
15:00 Return boat trip from Snorkelling
15:45 Walk from Aquaworld Marina to hotel

*Minimum of 10 people required*

Please note that sign-ups are required by 15th January 2018, please contact Meredith@fusion-conferences.com if you’d like to participate. Payment for the trip is required pre- conference, more details will be provided after completing the signing up.

This is a non-refundable fee should you later change your mind and decide not to participate in the trip.

Tulum Trip – Friday 2nd March 2018

Tulum is located 78 miles South of Cancun, about a 1:45 minute drive. It was discovered by John Stephens in 1842. Perched on top of a cliff facing the Caribbean Sea, it is the only entirely walled-in group of Mayan ruins ever discovered. Under the advice of an official English speaking tour guide, the group will go around the structures getting the history and spirit of the Mayan.

Price: $63.00
*please note prices do not include gratuity.

Includes:
-Air-conditioned vehicle
-Beverages on board: Soft drinks, bottled water (Estimated: 3 drinks per person)
-Individual bags of dry snacks on board
-Official Tourism Guides English/Spanish
-Admission fee in Tulum
-Round train transportation from Tulum parking lot to the archaeological zone.
-T.I. Escorts
-Tax    

Itinerary for Friday 2nd March 2018:

13:00 Depart from hotel
14:50 Estimated arrival to Tulum
15:00 – 17:00 Guided Tour / Free Time
17:00 Depart from Tulum
19:50 Estimated arrival to Hotel.

*Minimum of 10 people required*

Please note that sign-ups are required by Monday 15th January, please contact Meredith@fusion-conferences.com if you’d like to participate. Payment for the trip is required pre-conference, more details will be provided after signing up. Note this is a non-refundable fee should you later change your mind and decide not to participate.

Chichen Itzá Group Tour – Saturday 3rd March 2018 

Chichén Itzá, recently nominated one of the new 7th Wonders of the World. Chichén Itzá is located 125 miles West of Cancun about 2:15 hrs. It is the most visited archaeological site on the Peninsula, famed for its extraordinary architecture beauty.

Price: $140 per person

*please note prices do not include gratuity.

Includes:

-Air-conditioned vehicles
-Beverages on board: Soft drinks, water (Estimated: 5 drinks per person)
-Individual bags of dry snacks on board
-Official Tourism Guides English/Spanish
-Admission fee at Chichen Itza
-Reserved Area at the restaurant
-Buffet lunch (includes 2 beverages)
-Typical Regional dances during lunch (by local people – not professional at no additional cost)
-Signs for the vehicles
-T.I. Escorts
-Federal Tax

Note: All food and beverages a la carte is subject to 10% TI Administrative Fee

Itinerary for Saturday 3rd March 2018:

07:15 hrs. Pick at hotel 
10:45 hrs. Visit the Suy Tun Ecotourism Center and the sacred Cenote.
12:15 hrs. Lunch at Suy Tun’s restaurant.
14:30 hrs. Chichen Itza’s guided tour.
17:45 hrs. Valladolid city stop.
19:00 hrs. Estimated arrival to the Hotel.

*Minimum of 5 people required*

Please note that sign-ups are required by 15th January 2018 please contact Meredith@fusion-conferences.com if you’d like to participate. Payment for the trip is required pre- conference, more details will be provided after completing the signing up.

This is a non-refundable fee should you later change your mind and decide not to participate in the trip.

Oral Presenters

Talk Deadline: 06 Nov 2017

We have a number of oral opportunities available at this meeting. To be considered for a talk, please register for the conference and you will be able to submit your abstract online and monitor the status of your abstract through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Please take note of the oral submission deadline:  
6th Nov 2017

Please check the conference programme carefully to note your presentation time (inclusive of Q&A) should you be accepted for an oral presentation. We recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference page.

Your Presentation on the Day

If you have prepared some slides to accompany your talk please ensure you bring these with you on a USB or portable file saving device.

For those presenting on the first day, please email your slides to us so we can have everything prepared and ready for the first session. Please email your slides to: admin@fusion-conferences.com

On the day of your presentation please make yourself known to the AV team who will be available in the conference room. If you have any animations or videos we do advise to run through the presentation with the AV tech to make sure everything is compatible. We also advise that all speakers make themselves known to the AV tech in the conference room immediately before your session beings. The AV tech will apply your microphone and provide a laser pointer should you have an accompanying presentation. We prefer speakers to use our master laptop to run presentations from, however, if you prefer to use your own laptop, please notify us in advance.

It is important that all speakers adhere to their presentation time and respect their fellow presenters. A visual traffic light aide will be available to warn presenters and the audience as your time decreases.

If you have any questions, please don’t hesitate to approach our AV tech or a member of the Fusion team.

Helpful Tips for Presentation Slides

Aspect Ratio:On Screen Show (16:9) and in Landscape Orientation.
Font Size: Minimum font size used should be 24pt. 
File Type: Please save your presentation in PPT or PPTS format. 
Video Clips: Please save these separately and do not build them into the PowerPoint. Videos will be played via the AV control desk using the master laptop.

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Posters

Poster Deadline: 15 Jan 2018

We have a number of poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and you will be able to submit your abstract online and monitor the status of your abstract through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Please take note of the poster submission deadline: 15th Jan 2018

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

During conference registration if you are presenting a poster please request a poster number from the registration desk. Please do not put up your poster without notifying a member of the Fusion team. Certain adhesive agents are not permitted at some venues therefore; Fusion will be the sole provider of all poster fixings.

You can display your poster from registration. Your poster can remain on display for the entire duration of the conference and we ask that posters are taken down on the final day of the meeting. The poster session is usually scheduled on Day 3, but please check the official programme for exact timings. Refreshments will be provided and the poster prizes will be awarded during the conference Gala Night that evening. 

2018 Nuclear Receptors Poster Prize

The conference chairs will be awarding 3 poster prizes for the best poster display and presentation. To be in with a chance of winning, submit your poster by 15 Jan 2017. The winners will be selected shortly after the Poster Session and the following prizes will be awarded: 1st Place $350, 2nd Place $250, 3rd Place $150.

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