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Home > Past Conferences > Neurogenesis Conference

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Neurogenesis Conference

Implications for Lifelong Development and Disease

02 Mar 2016 - 05 Mar 2016

Cancun, Mexico

Synopsis

This conference has now passed. Join us in Nassau, The Bahamas in 2019 for the 2nd series, view details here

Neural development is not restricted to embryonic or early postnatal stages but continuous throughout life in the mammalian brain. This conference will bring together leaders from diverse fields such as embryonic cortical development, adult neurogenesis, human imaging, and stem cell-based neural disease modelling to discuss recent advances in understanding the cellular and molecular mechanisms regulating neural stem cell activity, neuronal specification and functional significance of circuitries modified by the addition of new neurons. In addition, translational perspectives and implications for disease modelling will be covered. 

Target Audience

Junior (i.e., PhD students and postdocs) and senior scientists (i.e., group leaders and professors) and physician-scientists in academia, biotech and pharmaceutical companies who would like to gain a better understanding in mechanisms underlying the neurogenic process in the developing and adult brain in physiology and disease. Further, the audience will be interested to engage in discussions on state of the art in each of these areas. The confirmed list of speakers with the majority of academic and pharmaceutical industry leaders in the respective fields present will make this conference the major event in the field for 2016. 

Plenary Speakers

Dr. Onur Basak (Hubrecht Institute)
HOW NICHE SIZE CONTROLS ADULT NEURAL STEM CELL NUMBER AND LONGEVITY

Prof. Gordon Fishell
(NYU Langone Medical Center)
NON-CANONICAL WNT-SIGNALING REGULATES THE RATIO OF SOMATOSTATIN- AND PARVALBUMIN- EXPRESSING CORTICAL INTERNEURONS

Prof. Fred H. Gage (Salk Institute)
HOW CAN A NEW NEURON INTEGRATE IN AN ADULT BRAIN? 

Prof. Dr. Magdalena Götz (Institute of Stem Cell Research, Helmholtz Center Munich)
THE EMBO KEYNOTE LECTURE

Prof. Rene Hen (Columbia University)
IMAGING AND MANIPULATING YOUNG GRANULE CELLS: IMPLICATIONS FOR MOOD AND COGNITIVE DISORDERS

Prof. Rudolf Jaenisch (Whitehead Institute)
IPS CELL TECHNOLOGY AND DISEASE RESEARCH

Prof. Dr. Sebastian Jessberger (University of Zurich)

Prof. Dr. Gerd Kempermann (CRTD Dresden)
ADULT NEUROGENESIS: AN INDIVIDUALIZING EXPERIENCE 

Prof. Pierre-Marie Lledo (Institut Pasteur)
WHEN CORTICAL AFFERENTS NEED ADULT-BORN NEURONS TO INFLUENCE OLFACTION

Prof. Guo-li Ming (Johns Hopkins University)
DISSECTING THE INTEGRATION PROCESS OF ADULT GENERATED NEURONS 

Prof. Alejandro Schinder (Fundación Instituto Leloir)
REMODELING DENTATE GYRUS ARCHITECTURE AND FUNCTION BY NEW GRANULE CELLS 

Prof. Hongjun Song (Johns Hopkins University)

Invited Speakers

Prof. Dr. Benedikt Berninger (Universitätsmedizin Mainz)
MOLECULAR AND CELLULAR CONSTRAINTS OF TRANSCRIPTION FACTOR- INDUCED NEUROGENIC REPROGRAMMING 

Prof. Michael Bonaguidi (University of Southern California)
DIVERSITY AND PLASTICITY OF ADULT HIPPOCAMPAL NEURAL STEM CELLS 

Prof. Dr. Dieter Chichung Lie (Friedrich-Alexander University Erlangen-Nuremberg)
TRANSCRIPTIONAL REGULATION OF FUNCTIONAL MATURATION IN ADULT NEUROGENESIS 

Prof. Amelia J. Eisch (UT Southwestern Medical Center)
STIMULATION OF ENTORHINAL CORTEX-DENTATE GYRUS CIRCUITRY IS ANTIDEPRESSIVE 

Prof. Paul Frankland (Hospital for Sick Children)
MECHANISMS OF NEUROGENESIS-MEDIATED FORGETTING OF HIPPOCAMPAL MEMORIES 

Prof. Shaoyu Ge (Stony Brook University)
INITIATION OF CIRCUIT INTEGRATION AND UNDERLYING MECHANISMS OF ADULT-BORN NEURONS 

Prof. Yukiko Gotoh (University of Tokyo)
REGULATION OF NEURAL STEM CELL FATE DURING EMBRYOGENESIS AND IN THE ADULT 

Prof. Jenny Hsieh (UT Southwestern Medical Center)
TRANSCRIPTIONAL REGULATION OF ADULT NEUROGENESIS IN NORMAL AND EPILEPTIC BRAIN

Dr. Ravi Jagasia (Roche)
HUMAN NEUROGENESIS SCREENING AND BIOMARKER IDENTIFICATION USING EMBRYONIC DERIVED NEURONAL PRECURSORS

Prof. Mi-hyeon Jang (Mayo Clinic)
BUBR1 INSUFFICIENCY IMPAIRS ADULT HIPPOCAMPAL NEUROGENESIS AND COGNITIVE FUNCTION

Prof. Mirjana Maletić-Savatić (Baylor College of Medicine)
MEASURING NEUROGENESIS IN THE LIVE HUMAN BRAIN 

Prof. Dr. Ana Martin-Villalba (DKFZ)
STEM CELL HETEROGENEITY IN HOMEOSTASIS AND DISEASE

Prof. Alysson R. Muotri (University of California, San Diego)
LINE-1 RETROTRANSPOSITION IN THE BRAIN AND NEUROLOGICAL DISORDERS

Prof. Kinichi Nakashima (Kyushu University)
TLR9 SIGNALING IN MICROGLIA ENSURES HOMEOSTATIC NEUROGENESIS IN THE ADULT HIPPOCAMPUS 

Prof. Jack Parent (University of Michigan Medical School)
STRUCTURAL AND FUNCTIONAL CHANGES OF BIRTHDATED DENTATE GRANULE CELLS IN EXPERIMENTAL TEMPORAL LOBE EPILEPSY

Dr. Sergiu Pasca (Stanford University)
DEVELOPING IN VITRO HUMAN MODELS FOR NEURODEVELOPMENTAL DISORDERS 

Prof. Amar Sahay (Harvard University)
REJUVENATING AND RE-ENGINEERING AGING MEMORY CIRCUITS

Prof. Juan Song (UNC School of Medicine)
LOCAL CHOLECYSTOKININ-EXPRESSING INTERNEURON CIRCUIT REGULATES QUIESCENT NEURAL STEM CELLS IN THE ADULT HIPPOCAMPUS

Prof. Verdon Taylor (University of Basel)
REGULATION OF OLIGODENDROCYTE DIFFERENTIATION IN THE HIPPOCAMPAL NEUROGENIC NICHE

Prof. Nicolas Toni (University of Lausanne)
FINE STRUCTURE OF RADILA GLIA-LIKE NEURAL STEM CELLS IN THE ADULT HIPPOCAMPUS

Prof. Pierre Vanderhaeghen (University of Brussels)
FROM PLURIPOTENT STEM CELLS TO CORTICAL CIRCUITS 

Prof. Chun-Li Zhang (UT Southwestern Medical Center)
IN VIVO REPROGRAMMING FOR INDUCED ADULT NEUROGENESIS

Prof. Su- Chun Zhang (University of Wisconsin)
REGULATION OF HUMAN NEURAL CIRCUITS

Prof. Xinyu Zhao (University of Wisconsi-Madison)
DISSECTING NEUROGENIC IMPAIRMENT IN NEURODEVELOPMENTAL DISORDERS 

Sponsors

Sponsors

Report

Development 
Authors: Jenny Hsieh & Chun-Li Zhang

http://dev.biologists.org/content/143/10/1649

(link live until May 2017)

Programme

Wednesday 2nd March 2016

14:00 – 14:40

Registration

14:00 – 14:40

Welcome Lunch
*Kalmia Buffet Restaurant*

14:40 – 14:55

Opening Comments

14:55 – 15:30

Magdalena Götz
Institute of Stem Cell Research, Helmholtz Center Munich

THE EMBO KEYNOTE LECTURE

MECHANISMS OF NEUROGENESIS I
Session Chair: Gordon Fishell

15:30 – 16:00

Sebastian Jessberger
University of Zurich

 

16:00 – 16:15

Grigori Enikolopov
Stony Brook University

SIGNALING LANDSCAPE OF NEURAL STEM CELLS AND THEIR NICHE

16:15 – 16:45

Xinyu Zhao
University of Wisconsi-Madison

DISSECTING NEUROGENIC IMPAIRMENT IN NEURODEVELOPMENTAL DISORDERS

16:45 – 17:15

Refreshments

17:15 – 17:45

Michael Bonaguidi
University of Southern California

DIVERSITY AND PLASTICITY OF ADULT HIPPOCAMPAL NEURAL STEM CELLS

17:45 – 18:15

Pierre-Marie LLedo
Institut Pasteur

WHEN CORTICAL AFFERENTS NEED ADULT-BORN NEURONS TO INFLUENCE OLFACTION

18:15 – 18:30

Armen Saghatelyan
Université Laval

PRINCIPAL CELL ACTIVITY INDUCES SPINE RELOCATION OF ADULT-BORN INTERNEURONS IN THE OLFACTORY BULB

18:30 – 19:30

Poster Session I

19:30

Dinner at Leisure & Free Time

Thursday 3rd March 2016

07:00 – 08:00

Breakfast

MECHANISMS OF NEUROGENESIS II
Session Chair: Sebastian Jessberger

08:00 – 08:30

Hongjun Song
Johns Hopkins University

 

08:30 – 09:00

Kinichi Nakashima
Kyushu University

TLR9 SIGNALING IN MICROGLIA ENSURES HOMEOSTATIC NEUROGENESIS IN THE ADULT HIPPOCAMPUS

09:00 – 09:30

Jenny Hsieh
UT Southwestern Medical Center

TRANSCRIPTIONAL REGULATION OF ADULT NEUROGENESIS IN NORMAL AND EPILEPTIC BRAIN

09:30 – 10:00

Dieter Chichung Lie Friedrich-Alexander University Erlangen-Nuremberg

TRANSCRIPTIONAL REGULATION OF FUNCTIONAL MATURATION IN ADULT NEUROGENESIS

10:00 – 10:30

Refreshments & Group Photo

MECHANISMS OF NEUROGENESIS III
Session Chair: Hongjun Song

10:30 – 11:00

Fred H. Gage
Salk Institute

HOW CAN A NEW NEURON INTEGRATE IN AN ADULT BRAIN?

11:00 – 11:30

Verdon Taylor
University of Basel

REGULATION OF OLIGODENDROCYTE DIFFERENTIATION IN THE HIPPOCAMPAL NEUROGENIC NICHE

11:30 – 12:00

Shaoyu Ge
Stony Brook University

INITIATION OF CIRCUIT INTEGRATION AND UNDERLYING MECHANISMS OF ADULT-BORN NEURONS

12:00 – 12:30

Amelia Eisch
UT Southwestern Medical Center

STIMULATION OF ENTORHINAL CORTEX-DENTATE GYRUS CIRCUITRY IS ANTIDEPRESSIVE

12:30 – 12:45

Marlen Knobloch
University of Zurich

THE RATE OF FATTY ACID OXIDATION REGULATES QUIESCENCE IN ADULT NEURAL STEM CELLS

12:45 – 13:00

Ruth Beckervordersandforth
University of Erlangen Nürnberg

MITOCHONDRIAL METABOLISM CONTROLS EARLY LINEAGE PROGRESSION AND AGEING PHENOTYPES IN ADULT HIPPOCAMPAL NEUROGENESIS

13:00 – 16:00

Lunch at Leisure & Free Time

NETWORK REGULATION
Session Chair: Pierre-Marie Lledo

16:00 – 16:30

Alejandro Schinder
Fundación Instituto Leloir

REMODELING DENTATE GYRUS ARCHITECTURE AND FUNCTION BY NEW GRANULE CELLS

16:30 – 17:00

Juan Song
UNC School of Medicine

LOCAL CHOLECYSTOKININ-EXPRESSING INTERNEURON CIRCUIT REGULATES QUIESCENT NEURAL STEM CELLS IN THE ADULT HIPPOCAMPUS

17:00 – 17:30

Nicolas Toni
University of Lausanne

FINE STRUCTURE OF RADILA GLIA-LIKE NEURAL STEM CELLS IN THE ADULT HIPPOCAMPUS

17:30 – 17:45

Heather Cameron
NIMH/NIH

STRESS, AMBIGUITY, AND THE ROLE OF ADULT NEUROGENESIS IN RESPONSE TO THREAT

17:45 – 18:15

Refreshments

CELLULAR IDENTITY
Session Chair: Magdalena Götz

18:15 – 18:45

Gordon Fishell
NYU Langone Medical Center

NON-CANONICAL WNT-SIGNALING REGULATES THE RATIO OF SOMATOSTATIN- AND PARVALBUMIN- EXPRESSING CORTICAL INTERNEURONS

18:45 – 19:15

Yukiko Gotoh
University of Tokyo

REGULATION OF NEURAL STEM CELL FATE DURING EMBRYOGENESIS AND IN THE ADULT

19:15 – 19:30

Orly Lazarov
The University of Illinois at Chicago

MECHANISM AND FUNCTIONAL SIGNIFICANCE OF NEUROGENESIS: INSIGHT FROM COGNITIVE DYSFUNCTION

19:30 – 19:45

Alexey Terskikh
Sanford Burnham Prebys Medical Discovery Institute

DISTINCT EPIGENETIC FUNCTIONS OF SOX2 IN SELF-RENEWAL AND DIFFERENTIATION

19:45

Dinner at Leisure & Free Time

Friday 4th March 2016

07:00 – 08:00

Breakfast

FUNCTIONAL SIGNIFICANCE OF NEUROGENESIS
Session Chair: Gerd Kempermann

08:00 – 08:30

Gerd Kempermann
CRTD Dresden

ADULT NEUROGENESIS: AN INDIVIDUALIZING EXPERIENCE

08:30 – 09:00

Paul Frankland
Hospital for Sick Children

MECHANISMS OF NEUROGENESIS-MEDIATED FORGETTING OF HIPPOCAMPAL MEMORIES

09:00 – 09:30

Amar Sahay
Harvard University

REJUVENATING AND RE-ENGINEERING AGING MEMORY CIRCUITS

09:30 – 10:00

Refreshments

TARGETING NEUROGENESIS
Session Chair: Benedikt Berninger

10:00 – 10:30

Rene Hen
Columbia University

IMAGING AND MANIPULATING YOUNG GRANULE CELLS: IMPLICATIONS FOR MOOD AND COGNITIVE DISORDERS

10:30 – 11:00

Jack Parent
University of Michigan Medical School

STRUCTURAL AND FUNCTIONAL CHANGES OF BIRTHDATED DENTATE GRANULE CELLS IN EXPERIMENTAL TEMPORAL LOBE EPILEPSY

11:00 – 11:30

Ravi Jagasia
Roche

HUMAN NEUROGENESIS SCREENING AND BIOMARKER IDENTIFICATION USING EMBRYONIC DERIVED NEURONAL PRECURSORS

11:30 – 12:00

Ana Martin-Villalba
DKFZ

STEM CELL HETEROGENEITY IN HOMEOSTASIS AND DISEASE

12:00 – 17:00

Lunch at Leisure & Free Time

DETECTION OF NEUROGENESIS
Session Chair: Rene Hen

17:00 – 17:30

Onur Basak
Hubrecht Institute

HOW NICHE SIZE CONTROLS ADULT NEURAL STEM CELL NUMBER AND LONGEVITY

17:30 – 18:00

Mirjana Maletic-Savatic
Baylor College of Medicine

MEASURING NEUROGENESIS IN THE LIVE HUMAN BRAIN

MANIPULATING STEM CELL PROPERTIES
Session Chair: Guo-Li Ming

18:00 – 18:30

Chun-Li Zhang
UT Southwestern Medical Center

IN VIVO REPROGRAMMING FOR INDUCED ADULT NEUROGENESIS

18:30 – 19:00

Rudolf Jaenisch
Whitehead Institute

IPS CELL TECHNOLOGY AND DISEASE RESEARCH

19:00 – 20:00

Poster Session II, Cocktails & Refreshments

20:15 – 23:00

Gala Night & Poster Awards
*Lower Pool Deck*

Saturday 5th March 2016

07:00 – 08:00

Breakfast

NEUROGENESIS IN THE DISH
Session Chair: Yukiko Gotoh

08:00 – 08:30

Guo-Li Ming
Johns Hopkins University

DISSECTING THE INTEGRATION PROCESS OF ADULT GENERATED NEURONS

08:30 – 09:00

Pierre Vanderhaeghen
University of Brussels

FROM PLURIPOTENT STEM CELLS TO CORTICAL CIRCUITS

09:00 – 09:30

Su- Chun Zhang
University of Wisconsin

REGULATION OF HUMAN NEURAL CIRCUITS

09:30 – 09:45

Matteo Bergami
University Hospital Cologne

DIRECTED GENERATION OF CORTICAL-LIKE NEURONS IN THE ADULT HIPPOCAMPUS

09:45 – 10:00

Darcie Moore
University of Zurich

THE PRESENCE AND FUNCTION OF A DIFFUSION BARRIER IN MAMMALIAN NEURAL STEM CELLS AS A MECHANISM TO SEGREGATE AGE

10:00 – 10:30

Refreshments

DISEASE MODELING
Session Chair: Fred H. Gage

10:30 – 11:00

Benedikt Berninger
Universitätsmedizin Mainz

MOLECULAR AND CELLULAR CONSTRAINTS OF TRANSCRIPTION FACTOR- INDUCED NEUROGENIC REPROGRAMMING

11:00 – 11:30

Alysson Muotri
University of California, San Diego

LINE-1 RETROTRANSPOSITION IN THE BRAIN AND NEUROLOGICAL DISORDERS

11:30 – 11:45

Silvia Cappello
Max Planck Institute of Psychiatry

MODELING PERIVENTRICULAR HETEROTOPIA IN HUMAN ORGANOIDS WITH MUTATIONS IN FAT4 AND DCHS1

11:45 – 12:15

Sergiu Pasca
Stanford University

DEVELOPING IN VITRO HUMAN MODELS FOR NEURODEVELOPMENTAL DISORDERS

12:15 – 12:30

Closing Remarks

Sunday 6th March 2016

08:15 - 17:30

Chichen-Itzá Group Tour
 For those wanting to extend their stay we have organised a private day trip to Chichen-Itzá. Full details can be found under the ‘Group Activities’ tab on the conference website.

Speakers

Plenary Speakers

  • Prof. Rudolf Jaenisch
    Member, WIBR and Professor of Biology, M.I.T., Whitehead Institute for Biomedical Research
  • Dr. Fred Gage
    Adler Chair on Age Related Diseases, Salk Institute for Biological Studies
  • Prof. Gordon Fishell
    Associate Director, NYU Neuroscience Institute
  • Dr. Alejandro Schinder
    Principal Investigator, Instituto Leloir
  • Prof. Dr. Gerd Kempermann
    Professor, German Center for Neurodegenerative Diseases (DZNE) Dresden
  • Dr. René Hen
    Professor, Columbia University
  • Prof. Dr. Magdalena Götz
    Director, Institute of Stem Cell Research, Helmholtz Zentrum münchen
  • Dr. Onur Basak
    Researcher, Hubrecht Institute
  • Prof. Pierre-Marie Lledo
    Chairman of the Neuroscience Department, The Pasteur Institute

Invited Speakers

  • Prof. Dr. Yukiko Gotoh
    Professor, The University of Tokyo
  • Dr. Paul Frankland
    Senior Scientist, Hospital for Sick Children
  • Prof. Nicolas Toni
    Professor, University of Lausanne
  • Dr. Alysson Muotri
    Associate Professor, University of California San Diego
  • Prof. Kinichi Nakashima
    Professor, Graduate School of Medical Sciences, Kyushu University
  • Dr. Jack Parent
    Professor of Neurology, University of Michigan
  • Prof. Dr. Verdon Taylor
    Group Leader, University of Basel
  • Dr. Amar Sahay
    Assistant Professor, Center for Regenerative Medicine, MGH, Harvard Stem Cell Institute, Harvard Medical School
  • Dr. Xinyu Zhao
    Professor, University of Wisconsin-Madison
  • Prof. Dieter Chichung Lie
    Professor, Institute of Biochemistry, Friedrich-Alexander Universität Erlangen-Nürnberg
  • Prof. Shaoyu Ge
    Associate Professor, SUNY Stony Brook
  • Dr. Chun-Li Zhang
    Associate Professor, UT Southwestern Medical Center
  • Dr. Michael Bonaguidi
    Assistant Professor, USC
  • Dr. Jenny Hsieh
    Professor, The University of Texas at San Antonio
  • Prof. Su-Chun Zhang
    Professor, University of Wisconsin
  • Prof. Dr. Ana Martin-Villalba
    Professor and Division Head, German Cancer Research Center (DKFZ)
  • Prof. Pierre Vanderhaeghen
    Professor, ULB
  • Dr. Silvia Cappello
    Research Group Leader, Max Planck Institute of Psychiatry
  • Dr. Mirjana Maletic-Savatic
    Assistant Professor, Baylor College of Medicine
  • Dr Sergiu Pasca
    Assistant Professor, Stanford University
  • Prof. Dr. Benedikt Berninger
    Professor, Institute of Physiological Chemistry, University Medical Center Johannes Gutenberg University Mainz
  • Dr. Amelia Eisch
    Associate Professor of Psychiatry, UT Southwestern
  • Assist. Prof. Juan Song
    Assistant Professor, University of North Carolina, Chapel Hill
  • Dr. Ravi Jagasia
    Lab Head, F. Hoffmann-La Roche, Pharma Research and Early Development

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