The advent of single-molecule approaches has revolutionized our understanding of Molecular Biology. Combined advances in light microscopy, microfluidics, atomic force microscopy, and DNA sequencing have opened ways to bypass population averages and study individual molecular events for a variety of cellular processes.
This meeting aims to present the most recent advances in the mechanistic understanding of DNA metabolic processes at the single-molecule level, using both in vivo and in vitro approaches.
Sessions will cover various aspects of:
- DNA replication
- DNA recombination
- DNA repair
- Chromosome dynamics
Each session will be divided into in vitro and in vivo sections to highlight differences and complementary information obtained.
Take advantage of this fantastic opportunity for students! Register an academic at the earlybird rate of $1,815 and bring a student for only $850. Unfortunately, Postdocs are not eligible for this offer. Both registration packages include; accommodation for the 20, 21, 22 February 2020 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Academic registrations must be completed by 5th September 2019. Once registered, please contact Emily Bicknell to obtain a special registration link for your student.
Confirmed Keynote Speaker
Richard Ebright (Rutgers)
Confirmed Plenary Speakers
Vincent Croquette (l’ESPCI Paris)
Antoine van Oijen (University of Wollongong)
Maria Spies (The University of Iowa)
Sunney Xie (Harvard University)
Dorothy Erie (University of North Carolina at Chapel Hill)
Confirmed Invited Speakers
Ibrahim Cisse (Massachusetts Institute of Technology)
Johan Elf (Uppsala University)
Ilya Finkelstein (University of Texas at Austin)
Eric Galburt (Washington University in St. Louis)
Samir Hamdan (King Abdullah University of Science and Technology)
Achillefs Kapanidis (University of Oxford)
Linda Kenney (University of Illinois, Chicago)
Steve Kowalczykowski (University of California, Davis)
Ming Li (Chinese Academy of Sciences)
Tim Lohman (Washington University School of Medicine)
Kiyoshi Mizuuchi (NIH)
Xiaojun Ren (University of Colorado Denver)
Dave Sherratt (Oxford University)
Terence Strick (Institut de Biologie de l'École Normale Supérieure)
Gijs Wuite (Vrije Universiteit Amsterdam)
Jie Xiao (John Hopkins School of Medicine)
Researchers interested in the study of DNA metabolic events at the single molecule level: both in vitro and in vivo. Processes to be focused on – DNA replication, DNA recombination, DNA repair and transcription. In addition, single cell sequencing/genomics groups will also be targeted.
The single molecule field initially focused on experiments done in vitro. As the field has evolved and new technologies were developed, the understanding of single molecule behaviour in live cells has become increasingly important. The two fields have developed largely separately and by combining these into a single meeting will educate scientists on the value of and difficulties associated with both approaches to understanding key elements in genome maintenance, and the passage of genetic information from DNA to protein.