Registration deadlines

Early Bird - Expired

Talk Submission - Expired

Poster Submission - Expired

Registration Deadline - Expired

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Report

The third major conference titled Exploring DNA Repair Pathways as Targets for Cancer Therapy took place in Nassau, Bahamas from 23 to 26 February 2019. Attendees included scientific leaders in the field of DNA damage repair and cell cycle checkpoints, trainees in the field, industry leaders interested in developing drugs targeting DNA repair and cell cycle checkpoints and physicians interested in applying novel targeted therapeutics to their cancer patients.

The meeting was chaired by Dr. Helen Piwnica-Worms (Professor of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center) and Dr. Junjie Chen (Professor and Chain, Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center).

Faculty included Dr. Traver Hart (The University of Texas MD Anderson Cancer Center), Dr. Susan Domchek (University of Pennsylvania School of Medicine), Dr. Andre Nussenzweig (National Cancer Institute), Dr. Jan Van Deursen (Mayo Clinic), Dr. David Pellman (Dana Farber Cancer Institute), Dr. Jennifer Litton (The University of Texas MD Anderson Cancer Center), Dr. Joann Sweasy (Yale University School of Medicine), Dr. Stephan Gasser (Roche Glycart), Dr. Timothy Yap (The University of Texas MD Anderson Cancer Center), Dr. Bin Wang (The University of Texas MD Anderson Cancer Center), Dr. Sephen Kowalczykowski (University of California, Davis), Dr. Xiaochun Yu (City of Hope), Dr. Zhongsheng Yu (Washington University School of Medicine), Dr. Peter Glazer (Yale University School of Medicine), Dr. Rodney Rothstein (Columbia University Medical Center), Dr. Ranjit Bindra (Yale University School of Medicine), Dr. Zhenkun Lou (Mayo Clinic), Dr. Lee Zou (Massachusetts General Hospital), Dr. Mark O’Connor (AstraZeneca), Dr. Johannes Walter (Harvard Medical School), Dr. Agnel Sfeir (NYU School of Medicine), Dr. Xiaohua Wu (Scripps Research Institute), Dr. Ketan Patel (MRC), Dr. Li Lan (Massachusetts General Hospital), Dr. Jian Yuan (Mayo Clinic), Dr. Katharina Schlacher (The University of Texas MD Anderson Cancer Center).

The conference highlighted several exciting new findings in the field of DNA damage response and repair, spanning the gamut from bench to bedside and back to bench. New topics covered in this meeting including talks on immune checkpoints and the cGAS pathway. Speakers discussed mechanistic advances in NHEJ, BER, HRR, replication fork protection, and genomic stability. Roles of BRCA1/2 and additional pathway mediating homologous recombination repair (HRR) and fork protection were presented. Results from landmark clinical trials of Talazoparib (PARP1/2 inhibitor) in the neoadjuvant setting for newly diagnosed breast cancer patients with germline BRCA1/2 mutations were presented.  In addition, mechanisms of PARP inhibitor resistance along with novel PARP inhibitor combination therapies were discussed. Several presenters shared exciting results from synthetic lethal screens designed to target unique vulnerabilities of cancer cells. An inhibitor to PARG, an enzyme that releases polyI(ADP-ribose) from PARP substrates, was shown to exhibit synthetic lethality with HR deficiency. IDH1/2 mutants were shown to produce millimolar levels of 2HG, which in turn, inhibits lysine demethylases (KDM4A/B) making tumor cells sensitive to ATR and PARP inhibitors. Plans for clinical translation of these findings were discussed.

The meeting was highly interactive and generated discussions about current and future directions of the field.

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Synopsis

Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows the accumulation of multiple genetic alternations, which are essential for the initiation of tumorigenesis. This has been clearly illustrated to be the cause of several human cancer-prone syndromes and also revealed by recent human genome studies. On the other hand, defective DNA repair and checkpoint activation also make cancer cells more vulnerable for particular DNA damaging agents or inhibitors that specifically disrupt some of these checkpoint pathways. With the increasing understanding of defects in DNA repair and checkpoint control in tumorigenesis, there are extensive interests in exploring these deficiencies, especially taking advantage of the synthetic lethality concept and targeting particular DNA repair and checkpoint pathways for cancer therapy. The purpose of this conference is to bring together basic, translational and clinical investigators and discuss the current and future directions, opportunities and obstacles in the development of these anti-cancer modalities and how to best apply these concepts in clinical practice.

Key Sessions

  • Highlight recent advances in the field of DNA damage repair
  • Identify novel targets in DNA repair and checkpoint pathways
  • Explore the concept of synthetic lethality for cancer treatment
  • Assess the therapeutic potential of new anti-cancer modalities
  • Learn mechanisms of therapeutic resistance and ways to improve cancer therapy

Student Offer

Take advantage of this fantastic opportunity for students! Register an academic at the standard rate of $1,716 and bring a student for only $850. Unfortunately, Postdocs are not eligible for this offer. Both registration packages include; accommodation for the 23, 24 and 25 February 2019 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Academic registrations must be completed by 12 December 2018. Once registered, please contact Jack Peters to obtain a special registration link for your student.

Confirmed Invited Speakers

Jan van Deursen (Mayo Clinic)
Susan Domchek (University of Pennsylvania)
Stephan Gasser (Roche)
Peter Glazer (Yale University)
Traver Hart (MD Anderson Cancer Center)
Stephen Kowalczykowski (UC Davis)
Lei Li (MD Anderson Cancer Center)
Jennifer Litton (MD Anderson Cancer Center)
Zhenkun Lou (Mayo Clinic)
Andre Nussenzweig (NCI)
Mark O'Connor (AstraZeneca)
Ketan J. Patel (MRC Laboratory of Molecular Biology)
David Pellman (Harvard University)
Abena Redwood (MD Anderson Cancer Center)
Rodney Rothstein (Columbia University Medical Center)
Agnel Sfeir (New York University)
Joann Sweasy (Yale University)
Johannes Walter (Harvard University)
Bin Wang (MD Anderson Cancer Center)
Xiaohua Wu (Scripps Research Institute)
Tim Yap (MD Anderson Cancer Center)
Zhongsheng You (Washington University)
Xiaochun Yu (City of Hope)
Lee Zou (Massachusetts General Hospital)

 

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Speakers

Invited Speakers

Traver Hart

Assistant Professor, The University of Texas MD Anderson Cancer Center

Susan Domchek

Executive Director, Basser Ctr for BRCA; Director, MacDonald Cancer Risk Evaluation Ctr; Basser Professor in Oncology, Penn Medicine/Abramson Cancer Center

Jan van Deursen

Professor and Chair, Mayo Clinic

Jennifer Litton

Associate Professor, The University of Texas MD Anderson Cancer Center

Joann Sweasy

Professor, Yale University School of Medicine

Stephan Gasser

Prinicipal Scientist, Roche Glycart

Lei Li

Professor, The University of Texas MD Anderson Cancer Center

Timothy Yap

Associate Professor , MD Anderson Cancer Center

Bin Wang

Associate Professor, MD Anderson Cancer Center

Rodney Rothstein

Professor of Genetics & Development, Columbia University Medical Center

Ranjit Bindra

Associate Professor, Yale Medical School

Zhenkun Lou

Professor, Mayo Clinic

Lee Zou

Professor, Massachusetts General Hospital

Johannes Walter

Professor, Harvard Medical School

Agnel Sfeir

assistant professor, NYU school of medicine

Xiaohua Wu

Professor, The Scripps Research Institute

Ketan Patel

PI, MRC LMB

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Programme

SATURDAY 23RD FEBRUARY 2019

13:00 – 14:00

Student Networking Lunch

 

14:00 – 15:00

Registration & Welcome Reception

 

Identifying and Targeting Cell Vulnerabilities, From Bench to Bedside
Agnel Sfeir

15:00 – 15:10

Opening Comments

 

15:10 – 15:35

Lee Zou
Massachusetts General Hospital

TARGETING THE ATR CHECKPOINT PATHWAY IN CANCER THERAPY

 

15:35 – 16:00

Helen Piwnica-Worms MD Anderson Cancer Center

IDENTIFYING AND TARGETING VULNERABILITIES IN TREATEMENT-NAÏVE TRIPLE NEGATIVE BREAST CANCER

 

16:00 – 16:25

Mark OConnor
AstraZeneca

TARGETING THE DNA DAMAGE RESPONSE TO GENERATE NEW TREATMENTS FOR CANCER

 

16:25 – 16:50

Tim Yap
MD Anderson Cancer Center

TARGETING THE DNA DAMAGE RESPONSE IN THE CLINIC: LESSONS LEARNT AND THE PATH FORWARD

 

16:50 – 17:35

Refreshments

 

Identifying Novel Therapeutic Targets Via Genetic Screens
Johannes Walter

 

17:35 – 18:00

Traver Hart
MD Anderson Cancer Center

INTEGRATIVE ANALYSIS OF HUNDREDS OF CRISPR SCREENS YIELDS A GLOBAL VIEW OF INTERACTIONS BETWEEN CELLULAR PROCESSES

 

18:00 – 18:15

John Heath
Lady Davis Institute for Medical Research

EXPLORING THE NOVEL ROLES OF ZINC FINGER PROTEINS IN REGULATING GENOME STABILITY AND CELL CYCLE PROGRESSION

 

18:15 – 18:30

Abena Redwood
MD Anderson Cancer Center

CIA DISRUPTION PRESENTS AN EXPLOITABLE VULNERABILITY TO THERAPEUTIC AGENTS THAT PERTURB DNA FIDELITY

 

18:30 – 18:55

Junjie Chen
MD Anderson Cancer Center

CONTROL OF DNA DAMAGE RESPONSE AND TUMORIGENESIS

 

18:55 – 19:30

Meet the Poster Presenters I
Moderator:
Junjie Chen

 

19:00 – 19:30

Accompanying Guests Pre-Dinner Welcome Drinks

 

19:30

Dinner

 

SUNDAY 24TH FEBRUARY 2019

07:00 – 08:30

Buffet breakfast at The Market Place

Insights into Cellular Pathways that Maintain Genome Stability
Joann Sweasy

08:30 – 08:55

Zhongsheng You
Washington University

REPLICATION FORKS UNDER STRESS: SIGNALING THROUGH CA2+

08:55 – 09:20

Xiaochun Yu
City of Hope

THE ROLE OF POLY(ADP-RIBOSYL)ATION IN DNA DAMAGE REPAIR AND TUMOR SUPPRESSION

09:20 – 09:45

Bin Wang
MD Anderson Cancer Center

UBIQUITIN SIGNALING AT DNA DOUBLE STRAND BREAKS

09:45 – 10:30

Group Photo, Refreshments & Poster Viewing

10:30 – 10:55

Andre Nussenzweig
NCI

MAINTAINING GENOME STABILITY

10:55 – 11:20

Xiaohua Wu
Scripps Research Institute

PROTECTION OF DNA SECONDARY STRUCTURES AND ITS IMPLICATION IN CANCER THERAPY

11:20 – 11:55

Meet the Poster Presenters II
Moderator:
Junjie Chen

11:55 – 16:15

Lunch at Leisure & Free Time

Understanding and Exploiting BRCAness
Susan Domchek

16:15 – 16:40

Susan Domchek
University of Pennsylvania

CLINICAL TRIALS OF PARP INHIBITORS IN BRCA1/2 MUTATION CARRIERS

16:40 – 17:05

Ranjit Bindra
Yale School of Medicine

EXPLOITING ONCOMETABOLITE-INDUCED BRCAness – ON THE PATH FROM THE BENCH TO THE BEDSIDE

17:05 – 17:30

Stephen Kowalczykowski
UC Davis

SEEING AND UNDERSTANDING BRCA1, BRCA2 AND RAD51 FUNCTIONS IN CHROMOSOME MAINTENANCE BY HOMOLOGOUS RECOMBINATION

17:30 – 17:55

Jennifer Litton
MD Anderson Cancer Center

UPDATE ON PARP INHIBITORS IN CLINICAL PRACTICE FOR BREAST CANCER

17:55 – 20:00

Poster Session & Refreshments

20:00

Dinner

MONDAY 25TH FEBRUARY 2019

07:00 – 08:30

Buffet breakfast at The Market Place

Mechanisms of Old and New DNA Repair Pathways
Stephen Kowalczykowski

08:30 – 08:55

Johannes Walter
Harvard University

TRAIP IS A MASTER REGULATOR OF DNA INTERSTRAND CROSS-LINK REPAIR

08:55 – 09:10

John Fielden
University of Oxford

A NOVEL REPAIR COMPLEX FOR THE RESOLUTION OF TOP1-DNA ADDUCTS

09:10 – 09:35

Joann Sweasy
Yale University

BASE EXCISION REPAIR VARIANTS AND CANCER

09:35 – 10:00

Agnel Sfeir
New York University

INVESTIGATING THE IMPACT OF ALT-NHEJ DURING TUMOR PROGRESSION

10:00 – 10:25

Lei Li
MD Anderson Cancer Center

FANCONI ANEMIA AND COMPLEX DNA LESIONS

10:25 – 11:25

Poster Session & Refreshments

11:25 – 17:00

Lunch at Leisure & Free Time

12:30 – 16:00

Snorkel Trip (Signups required in advance)

Existing and Novel Regulation and Function of DNA Repair Processes
Katharina Schlacher

17:00 – 17:25

Peter Glazer
Yale University

ONCOMETABOLITES SUPPRESS HOMOLOGOUS RECOMBINATION DNA REPAIR BY INHIBITION OF CHROMATIN REMOLDING AT THE DNA DOUBLE STRAND BREAK

17:25 – 17:40

Razq Hakem
University Health Network

INTERPLAY OF DNA DOUBLE STRAND BREAK REPAIR AND NOTCH SIGNALING IN CANCER

17:40 – 17:55

Andrea Byrum
Washington University in St. Louis

MITOTIC REGULATORS TPX2 and AURORA A PROTECT DNA FORKS DURING REPLICATION STRESS BY COUNTERACTING 53BP1 FUNCITON

17:55 – 18:40

Refreshments

18:40 – 19:05

Rodney Rothstein
Columbia University Medical Center

GENOME INSTABILITY: THE GENETIC REPERCUSSIONS OF RAD5 OVEREXPRESSION

19:05 – 19:20

Kent Mouw
Dana-Farber Cancer Institute

NUCLEOTIDE EXCISION REPAIR (NER) PATHWAY ALTERATIONS AS CHEMO-IMMUNOTHERAPY BIOMARKERS

19:20 – 19:35

Jian Yuan
Mayo Clinic

THE ROLE OF THE BRD9-RAD51 AXIS IN CHEMORESISTANCE IN OVARIAN CANCER

20:00

Gala Dinner & Poster Awards


TUESDAY 26TH FEBRUARY 2019

07:00 – 08:30

Buffet breakfast at The Market Place

Emerging Concepts in Genome Stability and DNA Repair
Andre Nussenzweig

08:30 – 08:55

Stephan Gasser
Roche

THE ROLE OF ENDONUCLEASES IN THE GENERATION OF CYTOSOLIC DNA

08:55 – 09:20

Zhenkun Lou
Mayo Clinic

PD-L1 REGULATES THE DNA DAMAGE RESPONSE PATHWAY AND AFFECTS RADIOCHEMOSENSITIVITY

09:20 – 09:35

Katharina Schlacher
MD Anderson Cancer Center

RAD51C TUMOR SUPPRESSOR INHIBITS INFLAMMATION BY PROTECTING MITOCHONDRIAL REPLICATION DNA FORKS

09:35 – 10:00

David Pellman
Harvard University

MECHANISMS DRIVING RAPID GENOME EVOLUTION

10:00 – 10:30

Refreshments

10:30 – 10:55

Jan van Deursen
Mayo Clinic

CONTROL OF SENESCENT CELL IDENTITY

10:55 – 11:20

Ketan J. Patel
MRC Laboratory of Molecular Biology

 

11:20 – 11:35

Emanuela Dylgjeri
Thomas Jefferson University

NOVEL ROLES OF DNA-PK IN METABOLIC REGULATION

11:35 – 11:45

Closing Comments


Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Prices

Early Bird Full Price Additional Adult Additional Child Extra Night Adult Extra Night Child
Academic $1616 $1716 $684 $263 $281 $88
Industry $1616 $1716 $684 $263 $281 $88
Student $1327 $1427 $684 $263 $281 $88

All registration fees include 3 nights accomodation and meals during the conference period. Exact inclusions are detailed below.

What's Included in our Registration Fees?

Our registration fees are inclusive of the following during the conference period only:

- Conference registration 
- 3 Nights’ fixed accommodation (23, 24, 25 Feb 2019) on a single basis for academics and industry, on a shared basis for students
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Gala Dinner (includes an open bar)
- Room service 
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in both conference rooms and your guest room

What's Included in our Accompanying Adult Fees?

Our accompanying adult fees are inclusive of the following during the conference period only:

- 3 Nights’ fixed accommodation (23, 24, 25 Feb 2019) on a shared basis with a conference participant 
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Gala Dinner (includes an open bar)
- Room service 
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Accompanying persons are not permitted access to the conference.

What's Included in our Accompanying Child Fees?

Our accompanying child fees are inclusive of the following during the conference period only:

- 3 Nights’ fixed accommodation (23, 24, 25 Feb 2019) on a shared basis with the parent/s
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited bottled water and soft drinks
- Gala Dinner 
- Room service 
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Accompanying child fees are applicable for children aged 2-12 years. Children younger than 2 years stay free of charge with a parent. Children aged 13-17 years will be charged $366 per child. 18 years + will be classified as an adult at this venue (Melia Nassau Beach, Bahamas).

What's Included in our Extra Night Fees?

- 1 night’s accommodation for 1 person
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Room service 
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Extra night child fees are applicable for children aged 2-12 years. Children younger than 2 years stay free of charge with a parent. Children aged 13-17 years will be charged $122 per night, per child. 18 years + will be classified as an adult at this venue (Melia Nassau Beach, Bahamas).

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Venue

Melia Nassau Beach All Inclusive

Venue Rating
Currency
US Dollar (USD)
Address
Nassau W Bay St. Nassau Bahamas
Nearest Airport
Lynden Pindling International Airport

Overlooking one of the finest beaches in the world the Meliá Nassau Beach is surrounded by crystal blue waters and white sandy beaches. Located on the stunning Cable Beach, you are just a few minutes walk from the center, shops and restaurants. The beautiful Nassau Botanical Gardens are within easy reach (7km) and Lynden Pindling International Airport is situated only 9km away.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from Cilantro where you can experience the natural textures, aromas and flavors of Mexico, Nikkei, celebrated for its exquisite fusion of Japanese, Cantonese and Peruvian cuisine featuring a sushi bar and Teppanyaki tables, Estavida, an upbeat tapas lounge located in the hotel lobby serving innovative tapas and a wide selection of cocktails, Aqua, an A la carte restaurant specializing in exquisite, rustic Italian cuisine, The Market Place, where you will find an International buffet serving an array of exquisite dishes, O'Grille, an open air restaurant with fabulous views of the sea and pool serving casual beach fare and light bites and finally The Black Angus, a steakhouse featuring hip, contemporary jazz and modern decor, offering guests the finest quality prime cuts and the freshest ingredients.(This restaurant is not included in the all inclusive package, additional charges apply). The Gala Night takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment.  We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

  • 24 hour reception
  • Room service
  • 3 heated outdoor pools
  • Complimentary resort wide Wi-Fi (guest rooms, throughout hotel, beach and conference areas)   
  • 24-hour Fitness Center
  • 7 dining venues
  • 4 bars.
  • non-motorised water sports

The Bahamas is formed by over 700 islands, keys and islets located in the Atlantic Ocean and renowned for its warm sunshine, mild climate, fine, white sandy beaches, turquoise, crystal clear water and friendly people, making this the perfect environment to relax and unwind in your free time during the conference.

Location

The Melia Nassau Beach All-Inclusive is located right on the stunning Cable Beach just a few minutes away from the airport and city center; Nearby in Downtown Nassau you can experience the flavours of new foods at local restaurants, shop 'til you drop at Straw market or take a trip through time at the Pirates Museum. The beautiful Nassau Botanical Gardens are close by and water enthusiasts can enjoy non-motorized water sports right on property.

Nassau is the capital of the Bahamas. It lies on the island of New Providence, with neighboring Paradise Island accessible via Nassau Harbor bridges. The city has a hilly landscape and is known for it's fabulous beaches as well as its offshore coral reefs, popular for diving and snorkeling. It retains many of its typical pastel-colored British colonial buildings, like the pink-hued Government House.

 

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Transportation

Local Airport

Lynden Pindling International Airport (formally known as Nassau International Airport) is just a short 15-minute journey from the Melia Nassau Beach All-Inclusive and is easily accessible from almost every country in the world with many major international airlines providing direct or interconnecting flights daily.

Taxis

There’s no shortage of available taxi cabs at Lynden Pindling International Airport. Taxis are available outside the U.S., International and Domestic terminals. Taxis charge approximately $25 one way to the Melia Nassau Hotel, however charges may increase if there are more than two passengers and/or two large suitcases.

Pre-booked Airport Transfers

Should you wish to pre-book a taxi transfer from the airport, you will find there are several suppliers to chose from and prices range from $40 one way and $70 return trip for up to 3 people, taxes included. Please find below details of 3 transportation providers who are offering discounted rates for our groups. Please contact the supplier directly with any enquiries or booking requests.

HC Executive Transportation
Contact Name: Nicholas Knowles
Contact Telephone: +1 242-809-9418
Contact Email: hcexecutivetransportation@gmail.com
Website Link: www.hcets.net

The rates quoted below are for transfers from Lynden Pindling International Airport to Melia Nassau Beach hotel. Please quote ‘FUSION’ during initial enquiry to obtain the discounted rate.

Vehicle / No of Passengers

Price (One Way)

Price (Return Trip)

Car (maximum of 3 passengers)

$40.00 USD per vehicle

$70.00.00 USD per vehicle

SUV (maximum of 6 passengers)

$70 USD per vehicle

$110.00 USD per vehicle

Note: Tax included in above rates (12%). Gratuities optional. Pre-payment can be made at time of booking or to driver at time of service.

Simon's Transports Ltd
Contact Name: Jocelyne Casimir
Contact Telephone: Toll Free: 1-800-501-4964, International: 1-954-302-2505, Local: 1-242-364-5466
Contact Email: info@simonstransports.com 
Booking Link: https://simonstransportsbahamas.com/book-now-2/

The rates quoted below are for transfers from Lynden Pindling International Airport to Melia Nassau Beach hotel. Please quote ‘FUSION’ during initial enquiry to obtain the discounted rate, or you may book online via the booking link above where discounted rates are automatically applied.

Vehicle / No of Passengers

Price (One Way)

Price (Return Trip)

Car (maximum of 4 passengers)

$101.21 USD per vehicle

$181.36 USD per vehicle

SUV (maximum of 7 passengers)

$149.50 USD per vehicle

$266.57 USD per vehicle

Note: Tax and gratuities included in above rates (12% and 15%). Pre-payment is required no later than 24hours prior to scheduled transfer time.

Majestic Tours Ltd
Contact Name: Betty Fox
Contact Telephone: +1 242-322-2606 or +1 242-677-2610
Contact Email: betty@majesticholidays.com

The rates quoted below are for transfers from Lynden Pindling International Airport to Melia Nassau Beach hotel. Please quote ‘FUSION’ during initial enquiry to obtain the discounted rate,

Vehicle / No of Passengers

Price (One Way)

Price (Return Trip)

Car (maximum of 3 passengers)

$47.60 USD per vehicle

$95.20 USD per vehicle

SUV (maximum of 6 passengers)

$132.52 USD per vehicle

n/a

Shuttle Bus

n/a

$22.40 USD per person

Note: Taxes included in above rates (12%). Gratuities optional. Pre-payment (50%) is required at time of booking. The shuttle bus is not a private service therefore additional stops may be made along the journey.
A Majestic Tours hospitality desk is located in the lower lobby of the hotel and is open daily from 7:00am to 8:00pm.

 

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Local Activities

Several free activities are available within the resort and include:

  • Trip to Balmoral Island during your stay; a taxi boat to and from Balmoral Island and access to the VIP Balmoral Beachside is included.
  • Daily fitness activities: gym classes, yoga, zumba, pool aerobics, etc.
  • In the water: paddleboards, glass-bottom kayaks, ocean duo kayaks, reef-board zayaks, cabana floating mats, water hammocks, etc.
  • Workshops: jewellery making, henna tattoo, scent creation, Bahamian crafts, etc.
  • Classes: mixology, scuba diving, dancing, etc.
  • Friendly competitions: beach volleyball, beach soccer, ping pong, darts, water balloon toss, deep dive contest, etc.
  • Free shuttle to Baha Mar and direct access to its spectacular 100,000 sq. ft. casino, Royal Blue™ tournament player’s golf course with special rates for Meliá guests, tennis court, spa, retail outlets and over 30 dining venues and lounges

Half / Full Day Activities

Majestic Tours are a reputable and reliable company offering a variety of fascinating trips and excursions for either a half or full day.  To browse the range of tours and excursions available or to make a booking (individual/group) please follow the link below which will take you directly to the Majestic Tours website / booking system. Bookings can also be made on-site at the Majestic Tours desk, located in the lobby of the hotel alongside front desk. This is open daily from 7:00am to 9:00pm.

http://www.majestictoursbahamas.com/tours/#all

If you have any questions then please contact Majestic Tours directly (details below).

Contact Telephone: (+1242) 327-6000 ext. 860322
Contact Email: betty@majesticholidays.com

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Group Activities

Snorkel Trip – Monday 25th February 2019

We have arranged an exciting group activity for DNA Repair participants (accompanying guests welcome). Please find the details, timings and price for the activity below. Please note you are required to sign up by Friday 11th January 2019 for this activity and unfortunately, we cannot accept sign ups after this date nor onsite. Our apologies for any inconvenience this may cause.

This 3hr excursion will depart from Cable Beach at the Melia hotel. The first stop takes you to a Sea Turtle site where you will learn some interesting facts about the Sea Turtles followed by an exciting opportunity to swim with them. You will then head to the snorkel reef where you will be able to see many different types of coral, tropical fish, sea turtles, eels, spiny lobsters, and much more. Finally, you will have some free time to spend at Rose Island which is known for it’s beautiful beaches and lagoons.

Snorkel Tour: $75.00 per person to be paid on the day (USD or Bahamian Dollars accepted, a small charge will be applied for card payments).

Includes:
Snorkel equipment
Life jackets

Itinerary for Monday 25th February 2019:

12:30: Meet at main pool bar (in between the beach and towel hut)
13:00: Pickup from Cable Beach at Melia Hotel
13:10 – 13:40: Swim with sea turtles
13:40: Head to the reef for some snorkeling time
14:10 - 14:40: Snorkeling
14:40: Beach time at Rose Island
15:30: Return trip
16:00: Drop off at Cable Beach at Melia Hotel

*Minimum of 8 people required / Maximum capacity of 26*

Sign-ups are required by Friday 11th January 2019 should you wish to participate. To sign up, please email Jack Peters noting the names of any accompanying guests joining you on the activity.

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Childcare

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Oral Presenters

We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.

Your Presentation

On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.

Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.

We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.

Please make sure your presentation adheres to the following guidelines.

Aspect Ratio: On Screen Show (16:9)
File Type: Please save your presentation in PPT, PPTS or Keynote format.

Download Abstract Template

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Posters

We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you. 

Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.

Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.

Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.

Self-Introductions

Discussions are at the heart of this conference. We are therefore asking each poster presenter to give a 1minute self-introduction. We wish to ensure that your face as well as your interests and efforts are known to the other participants, so they may find you for discussions during the meeting. You should use this time to pitch your poster to the other conference attendees.

Here is what you should be prepared for.

You will be called to the front of the room and presenters will be called to the mic in alphabetical order by the session moderator. Note only 1minute is allocated per presenter, therefore, please try to keep your introduction as concise as possible following the format below.

Self-Introduction Format

  1. Your name and your PI's laboratory (if you are not the PI), your institute, your country.
  2. What are you working on?
  3. What is your question?
  4. Title of poster and your poster number (will be provided by Fusion at registration).
  5. What would you like to learn from others at this conference or get feedback on?

Slide Format

If you wish to accompany your self-introduction with a single slide, please ensure your slide is the following size; widescreen (16:9). We will be merging slides and if you use alternative formatting, the contents of your slide will be distorted. Animations are not permitted. A slide template can be found here.

Download Abstract Template

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

23 Feb 2019 - 26 Feb 2019

Nassau, Bahamas

Chairs

Junjie Chen
The University of Texas MD Anderson Cancer Center
Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

Conference History

12 Feb 2015, 15 Feb 2015

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy

Fiesta Americana Condesa, Cancun, Mexico

The first in the series of the Exploring DNA Repair Pathways as Targets for Cancer Therapy Fusion conferences.  Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows the ac...

More Information

27 Feb 2017, 02 Mar 2017

2nd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

Target DNA repair for Cancer Therapy

Fiesta Americana Condesa, Cancun, Mexico

Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows theaccumulation of multiple genetic alternations, which are essential for the initiation of tumorigenesis. This has been clearly illu...

More Information

23 Feb 2019, 26 Feb 2019

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

Melia Nassau Beach All Inclusive, Nassau, Bahamas

Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows the accumulation of multiple genetic alternations, which are essential for the initiation of tumorigenesis. This has been clearly ill...

More Information

20 Feb 2021, 23 Feb 2021

4th Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

Fiesta Americana Puerto Vallarta All Inclusive, Puerto Vallarta, Mexico

Defects in DNA damage repair and checkpoint control are underlying mechanisms driving tumorigenesis, since they allow for the accumulation of genetic alternations. In addition, defects associated with these pathways are the underlying cause of sev...

More Information

Supported By

Diamond
Media Partners
If you're interested in sponsoring this conference please contact us.