Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

The Tanz Centre for Research in Neurodegenerative Diseases

Report

The first Fusion Conference on ‘Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases’ was held in Nassau, Bahamas from 1^st to 4^th June, 2018. The conferenced attracted scientists from countries around the world such as; the USA, Canada, UK, Belgium, and Japan.

In the inaugural keynote lecture, Dr. David Holtzman from Washington University first presented a historical overview of apolipoprotein ApoE, the most well studied risk gene in association with the late onset of Alzheimer’s disease, and then discussed most recent discoveries on the role of ApoE in the control of tau aggregation. Dr. Li-Huei Tsai from Massachusetts Institute of Technology presented another plenary lecture on the topic of how microglia are activated in response to the challenge of neurodegeneration at the resolution of single cell levels and how LED lights, flicking at certain wavelength, activate microglia to engulf amyloid plaques. Both lectures received considerable attentions in the audience and discussions.

Almost all speakers in the conference presented outstanding lectures and discussed large portions of results that are not yet published. The programme had many standout talks across the four days. Dr. Yadong Huang from Gladstone Institute at UCSF investigated the effect of ApoE isoforms in IPSCs-derived neurons on synaptic dysfunctions and reported how to block ApoE4 toxicity through a chemical perturbation based on the difference of 3D structure of ApoE4 vs ApoE3. Dr. Mathew Blurton-Jones compared functional genomic datasets between iPSC-derived microglia from human and AD mouse models and identified unique signatures at different disease stages. Dr. Riqiang Yan from University of Connecticut health presented a not yet published finding that the C-terminal of CX3CL1 controls neurogenesis in the adult and increased expression of this fragment will reverse neuronal loss in a tau mouse model. Dr. Richard Mayeux from Columbia University discussed mutations of certain genes that are preferentially associated with certain racial groups. Ultra-rare mutations in SCRAP and FBXL7 are found to occur more frequently in the Caribbean Hispanic population while AKAP9 is a risk factor for the Africa American population. This study is important as it reveals race-dependent risky genes that are not easily seen in conventional genetic studies using whole genome populations. Dr. Philip L De Jager, another investigator from the Columbia University, presented large network dataset constructed from over four hundred individuals’ RNA seq results and identified gene modules unique to AD and related neuropathologies. One example is that upregulation of module 5 genes is associated with increased tau protein aggregation and accumulation, which correlates with declines in cognitive function. His data analyses also captured genes from activated microglia that are clustered in AD but less obvious in multiple sclerosis. Dr. Charles Glabe from UC Irvine discussed a captivating observation that amyloid plaques in one AD mouse model, 5xFAD model, evolve from intra neurons rather than the conventional thought of extra neuronal seeding theory. Chemical ablation of microglia will prevent formation of amyloid deposition. Dr. Sally Ishizaka, Director of the Immuno-Dementia Division at Eisai presented the strategy for human genetic-guided drug discovery for AD patients.

Two junior fellows, Drs. Cara Croft from University of Florida and Rita Cacace from University of Antwerp, also gave outstanding presentations. Cara reported the first in vitro 3D model for monitoring the progression of tau aggregation and fibrillary tangles while Rita discussed how chrosome 7q36 is associated with late onset of AD and revealed DPP6 is a candidate genes for AD, frontal temporal dementia based on their human and mouse genetic studies. Both talks won lengthy discussions from audience and their answers to these questions were satisfying and enlightening.

One of the most memorable components of the meeting was the active discussion after each presentation and during the refreshment breaks. There were many pressing questions and lengthy debates. One vehement argument, was even resolved through WWE-style fake fighting!

Many of the conference attendees not only contributed outstanding lectures but also recognized the need for a continuing conference in such a format. It was agreed by many that this conference has created a collegial format where attendees can have close interactions with each other and discuss the most important and updated scientific questions in the Alzheimer’s field. Holding this conference every two years is necessary as finding a cure for AD patients is so urgent and more efforts and funding resources are needed in order to enable this.

We would like to acknowledge the Conference sponsors and media partners; Eisai Ltd, Fusion Conferences, Alzheimer Disease & Associated Disorders and the Journal of Alzheimer's Disease. Without their support it would have been impossible to have held such a wonderful conference.

Conference Chairs Dr. Riqiang Yan and Dr. Peter St George-Hyslop, along with Plenary speaker Dr. Li-Huei Tsai, are currently deciding on a location and date for the second meeting. Once confirmed, all details will be released on this webpage and via Fusion Conferences’ social media.
A forthcoming meeting that may be of interest is the 2^nd Neurogenesis Conference, being held from March 5^th-8^th 2019 in Nassau, Bahamas. Oral and poster submissions are currently being accepted.

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Synopsis

Alzheimer’s disease (AD) is the most common age-dependent neurodegenerative disease, which affects over 5 million people in the US and over 35 million people worldwide. Currently, only four drugs are approved for alleviating symptoms in AD patients, and no new therapy has been approved for AD since 2003. Other related neurodegenerative diseases such as Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) are also age-dependent and lack effective therapies. Hence, finding cures for AD and other related neurodegenerative diseases is urgent and various approaches should be actively pursued. This planned conference intends to bring leading scientists and clinicians from all over the world to present their unpublished observations or findings to attendees and to share their vision or prospects on translational research. We expect that some presenters, either by talks or posters, will discuss our current state of knowledge in disease mechanisms, novel targets or approaches for identifying new therapeutic targets, and biomarkers for diagnosis or treatment readouts. We will also invite speakers who are conducting later stages of drug discoveries, including presentations of clinical trial results. The talks and poster presentations will include the most updated therapeutic strategies, newly discovered therapeutic targets, and recent clinical developments at various stages in the area of Alzheimer’s and related neurodegenerative diseases.

Key topics of discussion will include:
1) BACE1 inhibitors and/or γ-secretase modulators for reducing amyloid deposition
2) active and passive vaccination for enhancing clearance of amyloid plaques
3) Vaccines for reducing tau pathology
4) Antisense approaches for AD, PD and ALS therapy
5) Neural stem cell approaches for neurodegeneration
6) Inflammatory modulators for neurodegeneration.

The significance of having this conference is to provide a unique forum for the research community focusing on translational studies geared towards therapies in AD and related neurodegenerative diseases to come together and to discuss the latest advances and the future challenges in the field. It will also facilitate interactions between junior scientists and leading investigators in a relatively small conference setting.

Student Offer

Take advantage of this fantastic opportunity for students! Register an academic at the earlybird rate of $1,823 and bring a student for only $850. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 01, 02, 03 June 2018 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Once registered, please contact Jack Peters (jack@fusion-conferences.com) to obtain a special registration link for your student.

Plenary Speakers

David Holtzman (Washington University)
Li-Huei Tsai (MIT)

Invited Speakers

Elizabeth M. Bradshaw (Center for translational & Computational Neuroimmunology Columbia University Medical Center)
Matt Blurton-Jones (University of California, Irvine)
Guy Brown (University of Cambridge)
Guojun Bu (Mayo Clinic)
Rita Cacace (University of Antwerp)
Damian Crowther (AstraZeneca)
Philip De Jager (Center for translational & Computational Neuroimmunology Columbia University Medical Center)
Charles Glabe (University of California, Irvine)
Yadong Huang (Gladstone Institute)
Sally Ishizaka (Eisai)
Orly Lazarov (University of Illinois at Chicago)
Yueming Li (Memorial Sloan Kettering Cancer Center)
Richard Mayeux (Taub Institute at Columbia University)
Jennifer Pocock (University College London)
Domenico Praticò (Temple University)
Nikolaos Robakis (Mount Sinai)
Gerard D. Schellenberg (University of Pennsylvania Perelman School of Medicine)
Sangram S. Sisodia (The University of Chicago)
Giulio Taglialatela (University of Texas Medical Branch)
Giuseppinna Tesco (Tufts University)
Taisuke Tomita (University of Tokyo)
Jeffery M. Vance (University of Miami)
Robert Vassar (Northwestern University)
Huaxi Xu (Sanford Burnham Prebys Medical Discovery Institute)
Gang Yu (UT Southwestern)
Xiongwei Zhu (Case Western Reserve University)

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Speakers

Plenary Speakers

David Holtzman

Professor and Chair, Washington University in St. Louis

Li-Huei Tsai

Professor and Director, Picower Institute at MIT, MIT

Invited Speakers

Taisuke Tomita

Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo

Domenico Pratico

Professor, Temple University

Sally Ishizaka

Director, Immuno-Dementia, Eisai Inc.

Mathew Blurton-Jones

Associate Professor, University of California, Irvine

Orly Lazarov

Professor, The University of Illinois at Chicago

Charles Glabe

Professor, UC Irvine

Guojun Bu

Professor, Mayo Clinic

Gerard Schellenberg

Professor, Perelman School of Medicine, University of Pennsylvania

Giuseppina Tesco

Associate Professor, Tufts University

Robert Vassar

Professor, Northwestern University

Gang YU

Professor, University of Texas Southwestern Medical Center

Nikolaos Robakis

Professor, Mount Sinai Medical Cemter

Xiongwei Zhu

Professor, Case Western Reserve University

Elizabeth Bradshaw

Assistant Professor, Center for translational & Computational Neuroimmunology Columbia University Medical Center

Damian Crowther

Director, R&D, Neuroscience, AstraZeneca IMED Biotech Unit

Giulio Taglialatela

Professor and Vice Chair, University of Texas Medical Branch

Guy Brown

Professor, University of Cambridge

Rita Cacace

Postdoc, University of Antwerp

Huaxi Xu

Professor and Director of Neuroscience, Sanford Burnham Prebys Medical Discovery Institute

Yueming Li

Professor, Memorial Sloan Kettering Cancer Center

Yadong Huang

Senior Investigator/Professor, Gladstone Institutes/UCSF

Richard Mayeux

Professor, Taub Institute at Columbia University

Jeff Vance

professor, University of Miami

Jennifer Pocock

Senior Lecturer, University College London Institute of Neurology

sangram sisodia

Professor of Neurosciences, university of chicago

Philip De Jager

Professor of Neurology, Columbia University Medical Center

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Programme

FRIDAY 1^st JUNE 2018
14:00 – 14:45	Registration & Reception
14:00 – 14:45	Group Welcome Lunch
14:45 – 15:00	Opening Comments
PERSPECTIVES OF AD PATHOGENESIS Riqiang Yan and Peter St George-Hyslop
15:00 – 15:45	David Holtzman Washington University in St. Louis	APOE: ROLE IN AMYLOID-β ACCUMULATION AND IN TAU-MEDIATED NEURODEGENERATION
15:45 – 16:00	Zhengui Xia University of Washington	GENE-ENVIRONMENT INTERACTION BETWEEN LEAD AND APOLIPOPROTEIN E4 CAUSES COGNITIVE BEHAVIOR DEFICITS IN MICE
16:00 – 16:30	Guojun Bu Mayo Clinic	PATHOBIOLOGY AND THERAPEUTIC TARGETING OF APOE IN ALZHEIMER’S DISEASE
16:30 – 17:00	Sangram Sisodia University of Chicago	MODULATION OF AMYLOID DEPOSITION AND NEUROINFLAMMATION BY THE MICROBIOME
17:00 – 17:30	Refreshments
STEM CELLS IN AD Peter St. George-Hyslop
17:30 – 18:00	Orly Lazarov University of Illinois at Chicago	THERAPEUTIC AND DIAGNOSTIC POTENTIAL OF CREB IN ALZHEIMER’S DISEASE
18:00 – 18:30	Mathew Blurton-Jones University of California, Irvine	USING iPSC-DERIVED MICROGLIA AND HUMANIZED MICE TO STUDY THE FUNCTIONAL GENOMICS OF ALZHEIMERS DISEASE
18:30 – 19:00	Yadong Huang Gladstone Institute	ALZHEIMERS DISEASE MODELING AND DRUG SCREENING USING HUMAN IPSCS
19:00 – 19:30	Giulio Taglialatela University of Texas Medical Branch at Galveston	NEURAL STEM CELLS PROMOTE SYNAPTIC RESILIENCE TO DAMAGING Ab AND TAU OLIGOMERS VIA EXOSOME DELIVERY OF SELECTED MIRNA CARGOES
19:30 – 20:00	Riqiang Yan University of Connecticut	ENHANCING NEUROGENESIS TO REVERSE NEURONAL LOSS IN AD MOUSE MODELS
20:00	Group Dinner

SATURDAY 2^nd JUNE 2018
07:00 – 08:30	Breakfast
GENETICS AND EPIGENETICS OF AD Nikolaos Robakis
08:30 – 09:00	Gerard Schellenberg University of Pennsylvania Perelman School of Medicine	GENETIC STUDIES OF ALZHEIMERS DISEASE; IDENTIFICATION OF THERAPEUTIC TARGETS
09:00 – 09:30	Jeffery Vance University of Miami Health System	IDENTIFYING A PROTECTIVE FACTOR FOR APOE4
09:30 – 10:00	Richard Mayeux Taub Institute at Columbia University	GENETIC AND GENOMIC CONTRIBUTIONS TO ALZHEIMER’S DISEASE FROM THE CARIBBEAN ISLANDS
10:00 – 10:30	Rita Cacace University of Antwerp	EXPLORING THE MISSING GENETICS OF EARLY ONSET ALZHEIMER’S DISEASE: INSIGHTS FROM GENOMIC STUDIES IN AUTOSOMAL DOMINANT FAMILIES
10:30	Group Photo & Refreshments
10:45 – 16:15	Free Time
12:30 – 15:00	Snorkel Trip (Signups required in advance)
MOLECULAR MECHANISM OF AD PATHOGENESIS Guojun Bu
16:15 – 16:45	Peter St George-Hyslop University of Toronto	PHYSIOLOGICAL AND PATHOLOGICAL PHASE SEPARATION OF FUS IS REGULATED BY METHYLATION OF COOPERATIVE CROSS-DOMAIN CATION-PI INTERACTIONS AND INTERACTION WITH TNPO1
16:45 – 17:15	Domenico Praticò Temple University	THE LEUKOTRIENES PATHWAY AS A VIABLE THERAPEUTIC TARGET FOR TAUOPATHIES
17:15 – 17:45	Charles Glabe University of California, Irvine	PLX3397, A CSF1R/C-KIT INHIBITOR, ABLATES MICROGLIA AND BLOCKS THE ACCUMULATION OF INTRANEURONAL AMYLOID AND NEURITIC PLAQUES IN 5XFAD MICE
17:45 – 18:15	Refreshments
18:15 – 18:30	Cara Croft University of Florida	rAAV-MEDIATED BRAIN SLICE CULTURE MODELS TO DEVELOP TAU-BASED THERAPEUTICS
18:30 – 19:00	Sally Ishizaka Eisai	IMMUNO-DEMENTIA: HUMAN GENETICS-GUIDED DRUG DISCOVERY IN ALZEIMERS DISEASE
19:00 – 19:30	Taisuke Tomita University of Tokyo	NOVEL STRATEGIES FOR FACILITATION OF AMYLOID CLEARANCE IN THE BRAIN
19:30	Group Dinner

SUNDAY 3^rd JUNE 2018
07:00 – 08:30	Breakfast
NEURO-INFLAMMATION IN AD Robert Vassar
08:30 – 09:15	Li-Huei Tsai MIT	DECIPHERING THE IMMUNE RESPONSE OF MICROGLIA IN NEURODEGENERATION USING SINGLE-CELL RNA-SEQUENCING
09:15 – 09:45	Guy Brown University of Cambridge	NEURODEGENERATION CAUSED BY MICROGLIAL PHAGOCYTOSIS OF NEURONS
09:45 – 10:15	Elizabeth M. Bradshaw Center for translational & Computational Neuroimmunology, Columbia University Medical Center	ARE CD33 SIALIC-ACID DEPENDENT BINDING PARTNERS THERAPEUTIC TARGETS FOR AD?
10:15 – 10:45	Refreshments
10:45 – 11:15	Damian Crowther AstraZeneca	TREM2 METABOLISM AT THE CELL SURFACE: OPTIONS FOR THERAPEUTIC MODULATION
11:15 – 11:45	Jennifer Pocock University College London	TREM2 VARIANTS; RAMIFICATIONS FOR MICROGLIAL FUNCTION
11:45 – 12:15	Philip L. De Jager Center for translational & Computational Neuroimmunology, Columbia University Medical Center	POPULATION STRUCTURE OF HUMAN MICROGLIA: WHICH SUBSET OF MICROGLIA DO WE TARGET FOR TAU AND/OR AMYLOID PATHOLOGY?
12:15 – 17:30	Lunch at Leisure & Free Time
SECRETASES IN AD THERAPY Huaxi Hu
17:30 – 18:00	Robert Vassar Northwestern University	BACE1 AS A THERAPEUTIC TARGET FOR ALZHEIMER’S DISEASE
18:00 – 18:15	Brati Das University of Connecticut Health Center	DELETION OF BACE1 IN ADULT AD MICE REVERSES AMYLOID DEPOSITION AND IMPROVES SYNAPTIC FUNCTION
18:15 – 18:45	Giuseppina Tesco Tufts University	BACE1 UPS AND DOWNS: IMPLICATIONS FOR AD
18:45 – 19:15	Yueming Li Memorial Sloan Kettering Institute	HYPOXIA AND GAMMA-SECRETASE
19:45	*Gala Dinner*

MONDAY 4^th JUNE 2018
07:00 – 08:30	Breakfast
NOVEL TARGETS IN AD THERAPY Charles Glabe
08:30 – 09:00	Huaxi Xu Sanford Burnham Prebys Medical Discovery Institute	NOVEL ROLES FOR ALZHEIMER’S RISK GENE SORLA IN NEUROPROTECTION
09:00 – 09:30	Nikolaos Robakis Mount Sinai School of Medicine	PS1-REGULATED NEUROPROTECTIVE NMDAR COMPLEXES ARE INACTIVATED BY FAD MUTANTS
09:30 – 10:00	Gang Yu UT Southwestern	GAMMA-SECRETASE, GLIA/IMMUNE FUNCTION, AND ALZHEIMER’S DISEASE?
10:00 – 10:30	Refreshments
10:30 – 10:45	Ronald Davis Scripps Research Institute Florida	SMALL MOLECULE PROBES TARGETING NEURONAL MITOCHONDRIAL DYNAMICS INCREASE ATP PRODUCTION, RESCUE OXIDATIVE STRESS AND AMYLOID BETA MEDIATED NEUROTOXICITY
10:45 – 11:15	Xiongwei Zhu Case Western Reserve University	ABNORMAL MITOCHONDRIAL DYNAMICS AS A THERAPEUTIC TARGET OF ALZHEIMER DISEASE
11:15 – 11:30	Closing Comments by Peter St. George-Hyslop and Riqiang Yan

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Prices

Ticket Type	Early Bird	Full Price
Single Choose this option if you will be attending the conference alone, or if you will bring accompanying guests that will not attend the meeting.	$1823	$1923
Shared Choose this option if you wish to share with a colleague who is also attending the conference, or if you wish to be paired with another attendee of the same sex.	$1823	$1923
Student Choose this option if you are a student. Please note all students will be paired with another attendee of the same sex if a room sharer is not specified. If you wish to have your own room, please register under the Single option.	$1534	$1634

Additional Person

This is the cost for an additional adult or child to join you in the same room, for the entire conference period. Accompanying persons are not permitted access to the conference. If you wish to extend your stay, please see our 'Extra night' prices.

Adult

$684

Child

$255

Extra nights

Prices are per person.

Adult

$281

Child

$85

All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.

What's Included in our Registration Fees?

Our registration fees are inclusive of the following during the conference period only:

- Conference registration
- 3 Nights’ fixed accommodation (01, 02, 03 June 2018) on a single basis for academics and industry, on a shared basis for students/Postdocs
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Gala Dinner (includes an open bar)
- Room service (note a delivery charge will be applied)
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in both conference rooms and your guest room

What's Included in our Accompanying Adult Fees?

Our accompanying adult fees are inclusive of the following during the conference period only:

- 3 Nights’ fixed accommodation (01, 02, 03 June 2018) on a shared basis with a conference participant
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Gala Dinner (includes an open bar)
- Room service (note a delivery charge will be applied)
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Accompanying persons are not permitted access to the conference.

What's Included in our Accompanying Child Fees?

Our accompanying child fees are inclusive of the following during the conference period only:

- 3 Nights’ fixed accommodation (01, 02, 03 June 2018) on a shared basis with the parent/s
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited bottled water and soft drinks
- Gala Dinner
- Room service (note a delivery charge will be applied)
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Accompanying child fees are applicable for children aged 2-12 years. Children younger than 2 years stay free of charge with a parent. Children aged 13 years and older are classified as an adult at this venue (Melia Nassau Beach, Bahamas).

What's Included in our Extra Night Fees?

- 1 night’s accommodation for 1 person
- Breakfast, lunch and dinner available at all restaurants according to their operational hours (excluding Black Angus and Starbucks)
- Unlimited select brand liquors, wines by the glass, local domestic beer, bottled water and soft drinks
- Room service (note; a delivery charge will be applied)
- Guest room mini bar
- Non motorized water sports equipment
- Complimentary WIFI in your guest room

Important Note: Extra night child fees are applicable for children aged 2-12 years.

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Grants

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Venue

Melia Nassau Beach All Inclusive

Overlooking one of the finest beaches in the world the Meliá Nassau Beach is surrounded by crystal blue waters and white sandy beaches. Located on the stunning Cable Beach, you are just a few minutes walk from the center, shops and restaurants. The beautiful Nassau Botanical Gardens are within easy reach (7km) and Lynden Pindling International Airport is situated only 9km away.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from Cilantro where you can experience the natural textures, aromas and flavors of Mexico, Nikkei, celebrated for its exquisite fusion of Japanese, Cantonese and Peruvian cuisine featuring a sushi bar and Teppanyaki tables, Estavida, an upbeat tapas lounge located in the hotel lobby serving innovative tapas and a wide selection of cocktails, Aqua, an A la carte restaurant specializing in exquisite, rustic Italian cuisine, The Market Place, where you will find an International buffet serving an array of exquisite dishes, O'Grille, an open air restaurant with fabulous views of the sea and pool serving casual beach fare and light bites and finally The Black Angus, a steakhouse featuring hip, contemporary jazz and modern decor, offering guests the finest quality prime cuts and the freshest ingredients.(This restaurant is not included in the all inclusive package, additional charges apply). The Gala Night takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

24 hour reception
Room service
3 heated outdoor pools
Complimentary resort wide Wi-Fi (guest rooms, throughout hotel, beach and conference areas)
24-hour Fitness Center
7 dining venues
4 bars.
non-motorised water sports

The Bahamas is formed by over 700 islands, keys and islets located in the Atlantic Ocean and renowned for its warm sunshine, mild climate, fine, white sandy beaches, turquoise, crystal clear water and friendly people, making this the perfect environment to relax and unwind in your free time during the conference.

Venue Rating

Currency

US Dollar (USD)

Address

Nassau W Bay St. Nassau Bahamas

Nearest Airport

Lynden Pindling International Airport

Location

The Melia Nassau Beach All-Inclusive is located right on the stunning Cable Beach just a few minutes away from the airport and city center; Nearby in Downtown Nassau you can experience the flavours of new foods at local restaurants, shop 'til you drop at Straw market or take a trip through time at the Pirates Museum. The beautiful Nassau Botanical Gardens are close by and water enthusiasts can enjoy non-motorized water sports right on property.

Nassau is the capital of the Bahamas. It lies on the island of New Providence, with neighboring Paradise Island accessible via Nassau Harbor bridges. The city has a hilly landscape and is known for it's fabulous beaches as well as its offshore coral reefs, popular for diving and snorkeling. It retains many of its typical pastel-colored British colonial buildings, like the pink-hued Government House.

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Transportation

Local Airport

Lynden Pindling International Airport (formally known as Nassau International Airport) is just a short 15 minute journey from the Melia Nassau Beach All-Inclusive and is easily accessible from almost every country in the world with many major international airlines providing direct or interconnecting flights on a daily basis.

Taxis

There’s no shortage of available taxi cabs at LPIA. Taxis are available outside the U.S., International and Domestic terminals. Taxis charge $25 one way to the Melia Nassau Hotel, however if there are more than two passengers / two large suitcases then they will normally charge slightly more.

Pre-booked Airport Transfers

Majestic Tours Ltd are a reputable and trustworthy DMC based in Nassau. The Majestic Tours team will be on hand to provide a seamless transfer service to and from Lynden Pindling Airport. Majestic Tours will manage and confirm all transportation bookings, therefore please contact them directly with any questions or booking requests (details below).

Contact Name: Betty Fox
Contact Telephone: +1 242-322-2606 or +1 242-677-2610
Contact Email: betty@majesticholidays.com

To receive the rates below, please specify that you are with Fusion Conferences. Pre-booked airport transfer rates to and from LPIA / Melia Nassau Beach hotel are as follows.

Vehicle / No of Passengers	Price (One Way)	Price (Return Trip)
Shuttle Bus * ~	n/a	$21.50 USD per person
Car (maximum of 3 passengers) *	$46.00 USD per vehicle	$91.40.00 USD per vehicle
SUV (maximum of 8 passengers) *	$129.25 USD per vehicle	n/a

Note:
- The shuttle bus is not a private service therefore other stops may be made along the journey.
- 7.5% tax is included. Gratuities optional.
- No unauthorized stops will be made.
- No smoking, food or beverage is permitted on the buses.
- The driver will assist with loading / off-loading of luggage.
- All drivers and personnel are dressed in uniform.

If you wish to cancel your transfer, please inform Majestic Tours at least 72hours in advance for car bookings and 48hours in advance for bus/van bookings, otherwise full cancellation charges will apply. If you fail to inform Majestic Tours of any amendments to your travel schedule and consequently do not turn up at the date and time booked, full cancellation charges will apply for no shows.

Upon arrival at the airport, uniformed Majestic Tours representatives will be stationed outside of the terminal with the appropriate signage to meet you.

When you depart from the hotel, please wait at the front door of the hotel for your transfer. Majestic Tours will schedule departure times 2.5 – 3 hours prior to your flight departure time.

Please note that payment is required at the time of booking. Payment can be made over the phone with Majestic Tours or they will provide you with a form to complete and sign for processing. When payment has been processed you will be sent a voucher to confirm your booking. Please print this voucher and hand it to your Majestic Tours rep prior to departure from the airport.

Majestic Tours Desk

The Majestic Tours desk is located in the lobby of the hotel alongside front desk. This is open daily from 7:00am to 9:00pm.

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Local Activities

Several activities are available within the resort and include:

Sports: Volleyball / basketball
Fitness classes
Snorkeling
Kayaking

Half / Full Day Activities

Majestic Tours are a reputable and reliable company offering a variety of fascinating trips and excursions for either a half or full day. To browse the range of tours and excursions available or to make a booking (individual/group) please follow the link below which will take you directly to the Majestic Tours website / booking system. Bookings can also be made on-site at the Majestic Tours desk, located in the lobby of the hotel alongside front desk. This is open daily from 7:00am to 9:00pm.

http://www.majestictoursbahamas.com/tours/#all

If you have any questions then please contact Majestic Tours directly (details below).

Contact Name: Betty Fox
Contact Telephone: +1 242-322-2606 or +1 242-677-2610
Contact Email: betty@majesticholidays.com

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Group Activities

Snorkel Trip – Saturday 2nd June 2018

We have arranged an exciting group activity for the Alzheimer’s participants. Please find the details, timings and price for the activity below. Please note you were required to sign up in advance for the activities and I’m afraid we cannot accept any further sign ups. We apologise for any inconvenience.

This 2hr excursion will depart from Cable Beach at the Melia hotel. Firstly, you will visit the Sea Turtle site where you will learn some interesting facts and then get to swim with them. Finally, you will head to the snorkel site where you will be able to see many different types of coral, tropical fish, sea turtles, eels, spiny lobsters, and much more.

Snorkel Tour: $50.00 per person (USD or Bahamian Dollars accepted, a charge will be applied for card payments).

Includes:
Snorkel equipment

Life jackets

Itinerary for Saturday 2^nd June 2018:

12:30: Meet at Cable Beach
13:00: Pickup from Cable Beach at Melia Hotel
13:10: Arrive to the turtle location
13:20: Swim with sea turtles
13:50: Head to the reef for some snorkeling time
13:55 – 14:55: Snorkeling
15:00: Drop off at Cable Beach at Melia Hotel

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Childcare

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Oral Presenters

We have a number of oral opportunities available at this meeting. To be considered for a talk, please register for the conference and you will be able to submit your abstract online and monitor the status of your abstract through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Please take note of the oral submission deadline: 30 April 2018.

Please check the conference programme carefully to note your presentation time (inclusive of Q&A) should you be accepted for an oral presentation. We recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference page.

Your Presentation on the Day

If you have prepared some slides to accompany your talk please ensure you bring these with you on a USB or portable file saving device.

For those presenting on the first day, please email your slides to us so we can have everything prepared and ready for the first session. Please email your slides to: admin@fusion-conferences.com

On the day of your presentation please make yourself known to the AV team who will be available in the conference room. If you have any animations or videos we do advise to run through the presentation with the AV tech to make sure everything is compatible. We also advise that all speakers make themselves known to the AV tech in the conference room immediately before your session beings. The AV tech will apply your microphone and provide a laser pointer should you have an accompanying presentation. We prefer speakers to use our master laptop to run presentations from, however, if you prefer to use your own laptop, please notify us in advance.

It is important that all speakers adhere to their presentation time and respect their fellow presenters. A visual traffic light aide will be available to warn presenters and the audience as your time decreases.

If you have any questions, please don’t hesitate to approach our AV tech or a member of the Fusion team.

Helpful Tips for Presentation Slides

Aspect Ratio: 16:9 in Presenter View, Landscape in Orientation
Font Size: Minimum font size used should be 24pt.
File Type: Please save your presentation in PPT or PPTS format.
Video Clips: Please save these separately and do not build them into the PowerPoint. Videos will be played via the AV control desk using the master laptop.

Download Abstract Template

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Posters

We have a number of poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and you will be able to submit your abstract online and monitor the status of your abstract through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Please take note of the poster submission deadline: 30 April 2018.

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

During conference registration if you are presenting a poster please request a poster number from the registration desk. Please do not put up your poster without notifying a member of the Fusion team. Certain adhesive agents are not permitted at some venues therefore; Fusion will be the sole provider of all poster fixings.

You can display your poster from registration. Your poster can remain on display for the entire duration of the conference and we ask that posters are taken down on the final day of the meeting. The poster session is usually scheduled on Day 3, but please check the official programme for exact timings. Refreshments will be provided and the poster prizes will be awarded during the conference Gala Night that evening.

Download Abstract Template

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Conference History

01 Jun 2018, 04 Jun 2018

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Melia Nassau Beach All Inclusive, Nassau, Bahamas

Alzheimer’s disease (AD) is the most common age-dependent neurodegenerative disease, which affects over 5 million people in the US and over 35 million people worldwide. Currently, only four drugs are approved for alleviating symptoms in AD p...

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07 May 2025, 10 May 2025

3rd Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases

Avra Imperial, Chania, Crete

Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, FTS and ALS affect over 5 million people in the US and over 35 million people worldwide. Alzheimer’s disease (AD) is the most common age-dependent neurodegenerative dis...

More Information

Supported By

Silver

Media Partners

If you're interested in sponsoring this conference please contact us.

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

01 Jun 2018 - 04 Jun 2018

Nassau, Bahamas

Chairs

Riqiang Yan

University of Connecticut Health Center

Peter St George-Hyslop

The Tanz Centre for Research in Neurodegenerative Diseases

Cant see images? See gallery on Flickr

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Report

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Synopsis

Student Offer

Plenary Speakers

Invited Speakers

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Speakers

Plenary Speakers

Invited Speakers

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Programme

FRIDAY 1st JUNE 2018

SATURDAY 2nd JUNE 2018

MONDAY 4th JUNE 2018

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Prices

What's Included in our Registration Fees?

What's Included in our Accompanying Adult Fees?

What's Included in our Accompanying Child Fees?

What's Included in our Extra Night Fees?

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Grants

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Venue

Melia Nassau Beach All Inclusive

Location

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Transportation

Local Airport

Taxis

Pre-booked Airport Transfers

Majestic Tours Desk

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Local Activities

Half / Full Day Activities

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Group Activities

Snorkel Trip – Saturday 2nd June 2018

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Childcare

Supported By

Silver

Media Partners

Targeting Therapy of Alzheimer’s and Related Neurodegenerative Diseases Conference

Oral Presenters

Your Presentation on the Day

Helpful Tips for Presentation Slides

FRIDAY 1^st JUNE 2018

SATURDAY 2^nd JUNE 2018

MONDAY 4^th JUNE 2018