Registration deadlines

Early Bird - Expired

Talk Submission - Expired

Poster Submission - Expired

Registration Deadline - Expired

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Report

The 2016 conference focused on insights into dynamic DNA and RNA complexes acting in DNA damage response and cancer and comprising targets for advanced cancer interventions and for understanding and preventing carcinogenesis. Returning conference chairs, Sir Tom Blundell (FRS, FMedSci, Department of Biochemistry, University of Cambridge, UK) and Dr. John Tainer (Director (SIBYLS Advanced Light Source, Professor, MD Anderson Cancer Center, Houston, Texas, USA) brought together under one roof many of the people driving advances in defining the relevant structural biology and mechanisms, in order to enable uniquely productive and informative interactions for those working on DNA damage responses and cancer. The meeting emphasized informal as well as formal discussions in concert with informative talks and poster sessions.

The talks concerned the frontiers of structural biology for DNA and RNA damage responses and cancer. Highlights on damage responses included cutting-edge structural and single-molecule approaches to characterize damage recognition, ribonucleotide repair, non-coding RNAs, the connection of inflammation with DNA damage, and epigenetics in the repair responses. Discussion was vigorous and informative but the chairs kept the meeting on time to preserve time for informal discussions and subgroup meetings on collaborations. The conference venue had breath-taking views of the Caribbean Sea and white sandy beaches that facilitated informal as well as formal interactions and conversations. One thing that differentiates this conference from others is the combination of top researchers with younger investigators and the very effective interactions among them.

The Poster Session was extremely successful and generated many interactive discussions. We were delighted to award five prizes to the following winners;

1st Place - Ms. Julia Reinert
2nd Place - Ms. Somaira Nowsheen
3rd Place - Ms. Elizabeth O'Brien
4th Place - Mr. Shun-Hsiao Lee
5th Place - Mr. Cory Rice

The Closing Comments by Walter Chazin and Tom Blundell generated a vibrant discussion linking DNA repair enzymes to changes in expression and even animal behavior. There was the feeling that there is an increasing need to form partnerships between creative talent in the academic sector with innovation and technical advances being championed by industry. Overall, several insights were discussed. During the conference collaborations were established, which may well lead to some of the next breakthrough results.

The meeting was expertly organized and supported by Fusion Conferences, Ltd.  We thank Laura Trundle and her team for their helpful interactions with the organisers and participants.

Supported By

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If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Synopsis

This conference will focus on insights into dynamic DNA and RNA complexes involved in the damage response and cancer. It will emphasize informal as well as formal discussions together with informative talks and poster sessions. DNA repair is a target for advanced cancer interventions. DNA repair systems are also essential for preventing carcinogenesis. The 2016 conference will focus on dynamic complexes and the control of biological outcomes relevant to cancer biology and the development of new therapeutic targets and strategies. Talks will include highlights on damage responses including cutting-edge structural and single-molecule approaches to characterize damage recognition, ribonucleotide repair, non-coding RNAs, the inflammation – damage connection, and epigenetics in the repair responses.

Key Sessions

Key sessions will include emerging results and breakthrough methods concerning:

  1. DNA and RNA complexes
  2. Chromatin Remodeling
  3. Post-translational modifications
  4. Interface of repair with Replication, Transcription and Recombination
  5. RNA responses to damage
  6. Pathway selection & cross-talk
  7. Damage signaling and processing
  8. DNA repair and disease

Confirmed Speakers

Walter Chazin (Vanderbilt)
'WHAT ARE THOSE Fe-S CLUSTERS DOING?'

Wei Yang (NIH)
'ENZYME CATALYSIS BY A HIT-AND-RUN METAL ION' 

Lorena S. Beese (Duke University Medical Center)

Susan Lees-miller (University of Calgary)
'APLF IS INTRINSICALLY FLEXIBLE AND STABILIZES AN EXTENDED FUNCTIONAL CORE COMPLEX FOR EFFICIENT NON-HOMOLOGOUS END JOINING'

Magnar Bjorås (Oslo University Hospital)
'MODULATING BEHAVIOR BY OXIDATIVE DNA BASE LESION REPAIR'

Tom Ellenberger (Washington University in St. Louis)
'TARGETING POLY(ADP-RIBOSE) TURNOVER FOR CANCER THERAPY'

Sheila David (UC Davis)
'MUTYH, CHEMISTRY AND CANCER: IT’S ALL ABOUT THE BASE'

Bennett Van Houten (University of Pittsburgh and Carnegie Mellon University)
'SINGLE MOLECULE ANALYSIS OF DNA REPAIR ENZYMES REVEALS A NOVEL “RECOGNITION AT DISTANCE” MECHANISM'

Stephen West (The Francis Crick Institute)
'ACTIVATION OF MUS81 STRUCTURE-SELECTIVE ENDONUCLEASE BY FORMATION OF THE SMX COMPLEX'

Dorothy Erie (University of North Carolina)
'CHARACTERIZATOIN OF THE ASSEMBLY OF MUTS AND MUTL HOMOLOGS AT A MISMATCH'

Titia de Lange (The Rockefeller University)
'CHROMOTHRIPSIS FROM TELOMERE FUSIONS'

Karl-Peter Hopfner (Ludwig-Maximilians-University Munich)
'STRUCTURAL MECHANISM OF ATP-DEPENDENT DNA BINDING AND DNA END JOINING BY EUKARYOTIC Rad50'

Jessica Downs (University of Sussex)
'PROTECTIVE PACKAGING FOR DNA: THE ROLE OF THE PBAF AND INO80 CHROMATIN REMODELLING COMPLEXES IN MAINTAINING GENOME STABILITY'

Jean-Baptiste Charbonnier (Institute of Integrated Biology of the Cell)
'PIVOTAL ROLES OF MUTL HOMOLOGS IN DNA REPAIR AND RECOMBINATION'

Dale Wigley (Imperial College London)
'STRUCTURE AND MECHANISM OF ADDAB AND RECBCD COMPLEXES' 

Titia Sixma (Netherlands Cancer Institute)
'SNAPSHOTS OF DNA MISMATCH REPAIR: TRAPPING TRANSIENT STATES'

Samir Hamdan (King Abdullah University of Science and Technology)
'PROBABILISTIC ACTIVE SITE ASSEMBLY CONTROLS CATALYTIC SELECTIVITY IN HUMAN FLAP ENDONUCLEASE-1'

Takashi Ochi (University of Cambridge)
'SCAFFOLDS WITH STRINGS ATTACHED OF MULTI-PROTEIN ASSEMBLIES IN NON-HOMOLOGOUS END JOINING'

Steve Smerdon (Medical Research Council)
'THE MOLECULAR BASIS OF Nbs1-Mdc1 INTERACTIONS – NEW TRICKS FOR OLD DOGS!'

Terence Strick (University of Paris – Diderot)
'CORRELATIVE SINGLE-MOLECULE ANALYSIS OF DYNAMIC COMPLEXES IN DNA REPAIR'

Mark Glover (University of Alberta)
'MECHANISM OF RNF8 STIMULATION OF Ubc13 AND ROLE IN DNA DAMAGE SIGNALING'

Ilya Finkelstein (UT-Austin)
'SINGLE-MOLECULE VIEWS OF EUKARYOTIC DNA MISMATCH REPAIR'

Aidan Doherty (University of Sussex)
'UNRAVELING THE ROLES OF PRIMASE-POLYMERASES IN DNA REPLICATION AND REPAIR' 

Supported By

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Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Speakers

Invited Speakers

Eva Nogales

Prof, UC Berkeley

Sheila David

Professor of Chemistry, University of California, Davis

Ben Van Houten

Richard M. Cyert Professor of Molecular Oncology , University of Pittsburgh Cancer Institute

Scott Williams

Principal Investigator, NIH/NIEHS

Magnar Bjørås

Professor, Oslo University Hospital

Titia Sixma

head of division, Netherlands Cancer Institute

Jim Haber

Professor, Brandeis University

Steve Smerdon

Programme Leader, The Francis Crick Institute, UK

Titia de Lange

Leon Hess Professor, The Rockefeller University

Karl-Peter Hopfner

Professor, Gene Center

Dale Wigley

, Imperial College London

Takashi Ochi

Research Associate, University of Cambridge

Aidan Doherty

Professor of Biochemistry, University of Sussex

Alan Ashworth

President, UCSF Helen Diller Family Comprehensive Cancer Center

Lorena Beese

Professor, Duke University Medical Center

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Programme

DISCUSSION IS VALUED: 5 MINUTES IS SAVED FOR DISCUSSION AFTER EACH TALK

Monday 22nd February 2016

14:00 – 14:45

Registration

14:00 – 14:45

Group Welcome Lunch
*Kalmia Buffet Restaurant*

HOMOLOGOUS RECOMBINATION INTERACTIONS
Session Chair: John Tainer

14:45 – 15:00

Welcome and Opening Remarks by Tom Blundell & John Tainer

15:00 – 15:20

Stephen West
Francis Crick Institute

ACTIVATION OF MUS81 STRUCTURE-SELECTIVE ENDONUCLEASE BY FORMATION OF THE SMX COMPLEX

15:25 – 15:45

Priscilla K Cooper
Lawrence Berkeley National Laboratory

XPG PARTNERS WITH BRCA1 AND BRCA2 IN HOMOLOGOUS RECOMBINATION TO MAINTAIN GENOME STABILITY

15:50 – 16:00

Kara Bernstein
University of Pittsburgh

THE CONCERTED FUNCTION OF THE SHU COMPLEX AND THE RAD51 PARALOGS IN RAD51 PRESYNAPTIC ASSEMBLY

16:05 – 16:15

Christian Biertuempfel
Max Planck Institute of Biochemistry

HUMAN HOLLIDAY JUNCTION RESOLVASE GEN1 USES A CHROMODOMAIN FOR EFFICIENT DNA RECOGNITION AND CLEAVAGE

16:20 – 16:40

Dale Wigley
Imperial College London

STRUCTURE AND MECHANISM OF ADDAB AND RECBCD COMPLEXES

16:45 – 17:15

Refreshments and Poster Set Up

17:15 – 17:35

Karl-Peter Hopfner
Gene Center

STRUCTURAL MECHANISM OF ATP-DEPENDENT DNA BINDING AND DNA END JOINING BY EUKARYOTIC Rad50

17:40 – 18:00

Steve Smerdon
Francis Crick Institute

THE MOLECULAR BASIS OF Nbs1-Mdc1 INTERACTIONS – NEW TRICKS FOR OLD DOGS!

18:05 – 18:15

Yaron Galanty
Gurdon Institute, University of Cambridge

SYSTEMATIC E2 SCREENING REVEALS A UBE2D-RNF138-CtIP AXIS PROMOTING DNA REPAIR

18:20 – 18:30

Aaron Alt
University of Sussex

STRUCTURE AND FUNCTION OF THE CHROMATIN TARGETING DOMAIN OF ONCOGENE CHD5

18:35 – 18:45

Christos Coucoravas
Karolinska Institutet

ROLE OF SPECIFIC NON-CODING RNAS IN DNA DOUBLE-STRAND BREAK REPAIR

18:50 – 19:00

General Discussion
Moderators: Susan Lees-Miller and John Tainer

19:00 – 19:45

Poster Highlights
Moderators: Susan Tsutakawa and David Finger
2 minute presentations per poster presenter

19:45

Dinner at Leisure

Tuesday 23rd February 2016

07:00 – 08:30

Breakfast

BREAK REPAIR
Session Chair: Tom Blundell

08:30 – 08:40

Tom Blundell        
University of Cambridge

Opening Comments

08:40 – 09:00

Susan Lees-Miller
University of Calgary

APLF IS INTRINSICALLY FLEXIBLE AND STABILIZES AN EXTENDED FUNCTIONAL CORE COMPLEX FOR EFFICIENT NON-HOMOLOGOUS END JOINING

09:05 – 09:15

Anthony Davis
UT Southwestern Medical Center

PHOSPHORYLATION OF Ku70 (OR SIMPLY Ku) DICTATES DNA DOUBLE-STRAND BREAK REPAIR PATHWAY CHOICE IN S PHASE

09:20 – 09:40

Takashi Ochi
University of Cambridge

SCAFFOLDS WITH STRINGS ATTACHED OF MULTI-PROTEIN ASSEMBLIES IN NON-HOMOLOGOUS END JOINING

09:45 – 10:05

Tom Blundell           
University of Cambridge

NON-HOMOLOGOUS END JOINING IN SPACE AND TIME: SCAFFOLDS, STRINGS AND STAGES

10:10 – 10:30

Jean-Baptiste Charbonnier
CEA-CNRS-Univ Paris Saclay, France

PIVOTAL ROLES OF MUTL HOMOLOGS IN DNA REPAIR AND RECOMBINATION

10:35 – 11:05

Refreshments and Informal Poster Viewing

11:05 – 11:25

Aidan Doherty
University of Sussex

UNRAVELING THE ROLES OF PRIMASE-POLYMERASES IN DNA REPLICATION AND REPAIR

11:30 – 11:40

Marcus Wilson
Lunenfeld-Tanenbaum Research Institute

STRUCTURAL BASIS FOR 53BP1 RECRUITMENT TO DNA DOUBLE-STRAND BREAKS

11:45 – 11:55

Alba Guarne
McMaster University

A NOVEL NON-CANONICAL FHA DOMAIN-BINDING INTERFACE MEDIATES THE INTERACTION BETWEEN RAD53 AND DBF4 PROTEINS

12:00 – 12:10

Luxin Sun
University of Alberta

STRUCTURAL INSIGHT INTO BLM RECOGNITION BY TOPBP1 IN MAINTENANCE OF GENOME STABILITY

12:15 – 12:35

Mark Glover
University of Alberta

MECHANISM OF RNF8 STIMULATION OF Ubc13 AND ROLE IN DNA DAMAGE SIGNALING

12:40 – 12:50

General Discussion
Moderators: Tom Blundell and Magnar Bjørås

12:50 – 16:00

Lunch at Leisure & Free Time

THE DAMAGE RESPONSE: TRANSCRIPTION, REPLICATION, AND CHROMOSOME DYNAMICS
Session Chair: Priscilla Cooper

16:00 – 16:10

Priscilla K Cooper
Lawrence Berkeley National Laboratory

Opening Comments

16:10 – 16:30

Yuan He
Northwestern University

STRUCTURAL BASIS OF EUKARYOTIC TRANSCRIPTION PROMOTER OPENING AT NEAR-ATOMIC RESOLUTION

16:35 – 16:45

Ivaylo Ivanov
Georgia State University

INTEGRATIVE MODELING OF MACROMOLECULAR ASSEMBLIES FROM LOW TO NEAR-ATOMIC RESOLUTION

16:50 – 17:00

Sylvie Doublié
University of Vermont

WHEN THE (3) END JUSTIFIES THE MEANS OR HOW A FAMILY A POLYMERASE SOLVES A MAJOR CHALLENGE

17:05 – 17:25

Jessica Downs
Genome Damage and Stability Centre

PROTECTIVE PACKAGING FOR DNA: THE ROLE OF THE PBAF AND INO80 CHROMATIN REMODELLING COMPLEXES IN MAINTAINING GENOME STABILITY

17:30 – 18:10

Refreshments and Informal Poster Viewing

18:10 – 18:20

Julia Reinert
Friedrich Miescher Institute

THE N-TERMINAL DOMAIN ENCIRCLES DNA TO ANCHOR YEAST RIF1 TO TELOMERIC AND NON-TELOMERIC DNA ENDS

18:25 – 18:45

Titia de Lange
The Rockefeller University

CHROMOTHRIPSIS FROM TELOMERE FUSIONS

18:50 – 19:00

General Discussion
Moderators: Priscilla Cooper and Karl-Peter Hopfner

19:00 – 20:30

Poster Session, Cocktails & Refreshments

20:30

Dinner at Leisure

Wednesday 24th February 2016

07:00 – 08:30

Breakfast

CATALYSIS AND DYNAMICS
Session Chair: Jane Grasby

08:30 – 08:40

Jane Grasby
University of Sheffield

Opening Comments

08:40 – 09:00

Wei Yang
National Institutes of Health

ENZYME CATALYSIS BY A HIT-AND-RUN METAL ION

09:05 – 09:15

Piero Bianco
University at Buffalo

THE ROLES OF SSB AND RecG IN STALLED DNA REPLICATION FORK RESCUE IN E.COLI

09:20 – 09:40

Walter Chazin
Vanderbilt University

WHAT ARE THOSE Fe-S CLUSTERS DOING?

09:45 – 09:55

Elizabeth OBrien
California Institute of Technology

A REDOX DNA-BINDING SWITCH IN THE [4FE4S] DOMAIN OF HUMAN DNA PRIMASE REGULATES ACTIVITY

10:00 – 10:10

David Rueda
Imperial College London

ACTIVATION-INDUCED DEOXYCYTIDINE DEAMINASE (AID) CO-TRANSCRIPTIONAL SCANNING AT SINGLE-MOLECULE RESOLUTION

10:15 – 10:45

Refreshments and Informal Poster Viewing

10:45 – 11:05

Terence Strick
CNRS/Institut Jacques Monod

CORRELATIVE SINGLE-MOLECULE ANALYSIS OF DYNAMIC COMPLEXES IN DNA REPAIR

 

 

11:10 – 11:30

Bennett Van Houten
University of Pittsburgh Cancer Institute

SINGLE MOLECULE ANALYSIS OF DNA REPAIR ENZYMES REVEALS A NOVEL “RECOGNITION AT DISTANCE” MECHANISM

11:35 – 11:45

Emily Beckwitt
University of Pittsburgh School of Medicine

SINGLE MOLECULE STUDIES OF XPA ON DNA

11:50 – 12:10

Samir Hamdan
King Abdullah University of Science and Technology

PROBABILISTIC ACTIVE SITE ASSEMBLY CONTROLS CATALYTIC SELECTIVITY IN HUMAN FLAP ENDONUCLEASE-1

12:15 – 12:25

General Discussion
Moderators: Jane Grasby and Brandt Eichman

12:25 – 16:00

Lunch at Leisure & Free Time

MISMATCH AND EXCISION REPAIR
Session Chair: Sylvie Doublié

16:00 – 16:10

Sylvie Doublié
University of Vermont

Opening Comments

16:10 – 16:30

Dorothy Erie
University of North Carolina

CHARACTERIZATOIN OF THE ASSEMBLY OF MUTS AND MUTL HOMOLOGS AT A MISMATCH

16:35 – 16:55

Titia Sixma
Netherlands Cancer Institute

SNAPSHOTS OF DNA MISMATCH REPAIR: TRAPPING TRANSIENT STATES

17:00 – 17:20

Lorena Beese
Duke University Medical Center

MMR AND EXOI FUNCTIONAL CONFORMATIONS

17:25 – 17:35

Susan Tsutakawa
Lawrence Berkeley National Laboratory

MEASURE THRICE-CUT ONCE IN STRUCTURE SPECIFIC FLAP ENDONUCLEASE

17:40 – 18:10

Refreshments and Informal Poster Viewing

18:10 – 18:30

Ilya Finkelstein
UT-Austin

SINGLE-MOLECULE VIEWS OF EUKARYOTIC DNA MISMATCH REPAIR

 

18:35 – 18:45

Brandt Eichman
Vanderbilt University

GLYCOSYLASE RECOGNITION OF DNA DAMAGE WITHOUT BASE FLIPPING ENABLES BASE EXCISION REPAIR OF BULKY LESIONS

18:50 – 19:00

Luay Joudeh
King Abdullah University of Science & Technology

DISSECTING THE STIMULATION OF FEN1 ACTIVITY BY PCNA ON FLAP SUBSTRATES AT THE SINGLE MOLECULE LEVEL

19:05 – 19:15

Jane Grasby
University of Sheffield

CELLULAR ACTIVE N-HYDROXYUREA INHIBITORS OF HUMAN FLAP ENDONUCLEASE 1

19:20 – 19:30

General Discussion
Moderators: Sylvie Doublié and Bennett Van Houten

20:00

Gala Dinner, Group Photo & Poster Awards
*Lower Pool Deck*

Thursday 25th February 2016

07:00 – 08:50

Breakfast

DNA DAMAGE, FUNCTIONAL FLEXIBILITY AND DISEASE
Session Chair: Walter Chazin

08:50 – 09:00

Walter Chazin
Vanderbilt University

Opening Comments

09:00 – 09:20

Tom Ellenberger
Washington University School of Medicine

TARGETING POLY(ADP-RIBOSE) TURNOVER FOR CANCER THERAPY

09:25 – 09:35

France Carrier
University of Maryland, Baltimore

THE HETEROGENOUS RIBONUCLEOPROTEIN A18 (hnRNP A18) PROMOTES TUMOR GROWTH BY INCREASING PROTEIN TRANSLATION OF SELECTED TRANSCRIPTS IN CANCER CELLS IN RESPONSE TO CELLULAR STRESS

09:40 – 09:50

Qian Wu
University of Cambridge

STRUCTURE OF BRCA1-BRCT/ABRAXAS COMPLEX REVEALS PHOSPHORYLATION-DEPENDENT BRCT DIMERIZATION AT DNA DAMAGE SITES

09:55 – 10:15

Sheila David
University of California, Davis

MUTYH, CHEMISTRY AND CANCER: IT’S ALL ABOUT THE BASE

10:20 – 10:50

Refreshments

10:50 – 11:00

Wilson Chun Yu Lau
University of Hong Kong

MOLECULAR ARCHITECTURE OF THE Ub-PCNA/Pol η COMPLEX BOUND TO DNA

11:05 – 11:25

Magnar Bjørås
Oslo University Hospital

MODULATING BEHAVIOR BY OXIDATIVE DNA BASE LESION REPAIR

11:30 – 11:50

John Tainer
MD Anderson

THE RISE OF THE MACHINES

11:55 – 12:05

General Discussion
Moderators: Walter Chazin and Tom Blundell

12:05 – 12:15

Closing Comments by Walter Chazin and Tom Blundell

Friday 26th February 2016

08:15 – 17:30

Chichen-Itzá Group Tour
 For those wanting to extend their stay we have organised a private day trip to Chichen-Itzá. Full details can be found under the ‘Group Activities’ tab on the conference website.


Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Prices

Early Bird Full Price Additional Adult Additional Child Extra Night Adult Extra Night Child
Academic $1579 $1679 $738 $284 $270 $71
Industry $1579 $1679 $738 $284 $270 $71
Student $1193 $1293 $738 $284 $270 $71

All registration fees include 3 nights accomodation and meals during the conference period. Exact inclusions are details below.

Accompanying child fees and extra night child fees are applicable for children aged 5-12 years of age. Children aged 13 years and older are classified as an adult at the Fiesta Americana Condesa. 

What's Included in our Registration Fees?

The Fiesta Americana Condesa, Cancun offers a 24hour all inclusive service. Our registration and additional adult/child fees are inclusive of the following;

- Accommodation for 3 Nights (22, 23, 24th February 2016)
- Breakfast, Lunch and Dinner – available at all restaurants according to operational hours or programmed events.
- International Bar available by the glass in restaurants and bars according to operational hours.
- Pool snacks and International Bar available by the glass at Pool Area
- Minibar including: soft drinks, domestic beer, bottled water and coffee. Refreshed daily
- 24 Hour Room Service
- In Room amenity – Bottle of wine, per room, per stay
- Gala Night Entry (includes an open bar)
- Complimentary WI-FI in guest rooms and conference rooms

Additional nights (per person) are inclusive of the following;

- Accommodation for 1 Night
- Lunch on day of arrival
- Dinner on day of arrival
- Breakfast on day of departure
- International bar available by the glass in restaurants and bars from lunch on day of arrival until breakfast on day of departure

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Venue

Fiesta Americana Condesa

Venue Rating
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa, Blvd.Kukulkán km 16.5 Zona Hotelera, Cancun, 77500 Mexico
Nearest Airport
Cancun International Airport

This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment.  We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

  • Lagoon Pool
  • Extensive Health Club and Spa
  • Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas

The Fiesta Americana Condesa, Cancun is the 2015 Winner of the Trip Advisor Certificate of Excellence and also received the Travellers Choice Award in 2014. 

The remains of ancient Mayan cities are scattered throughout the Yucatan Peninsula and no trip to Cancun would be complete without a visit to these majestic temples and pyramids set amongst lush tropical vegetation. We will be working very closely with a reputable tour company who will be organising trips to Tulum, Chichen Itza, Coba and Xcaret  to name a few, some of which may require a full day. Full day excursions will be arranged pre or post conference and may be on an individual or group booking so we would recommend booking extra nights to extend your stay as early as possible to avoid disappointment should these excursions be of interest to you and/or your party. For further information please contact us.

Location

Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.

Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Transportation

Travel Details

Cancun International airport is just a short 15 minute journey from the Fiesta Americana Condesa and is easily accessible from almost every country in the world with many major international airlines providing direct or interconnecting flights on a daily basis. 

Airport Transfers

Tropical Incentives are a reputable and trustworthy DMC based in Cancun. The Tropical Incentives team will be on hand to provide a seamless transfer service to and from Cancun International Airport. Tropical Incentives will manage and confirm all transportation bookings. To arrange transportation please contact Tropical Incentives directly via email, phone or the online booking facility (see link below).  

http://www.tropicalincentives.com/form_gpos/sales/cancun/2016/fusion-conference/

Conference Shuttle Service

Tropical Incentives have arranged a conference shuttle service which will run at scheduled times surrounding the conference. The conference shuttle schedule can be found below.

Arrivals (Cancun Airport – Fiesta Americana Condesa)

Sunday 21st February – Available at 1pm, 3pm, 5pm and 6:30pm
Monday 22nd February – Available at 1pm, 3pm, 5pm and 6:30pm
Wednesday 24th February – Available at 1pm, 3pm, 5pm and 6:30pm
Thursday 25th February – Available at 1pm, 3pm, 5pm and 6:30pm
Saturday 27th February – Available at 1pm, 3pm, 5pm and 6:30pm
Sunday 28th February – Available at 1pm, 3pm, 5pm and 6:30pm
Tuesday 1st March – Available at 1pm, 3pm, 5pm and 6:30pm
Wednesday 2nd March – Available at 1pm, 3pm, 5pm and 6:30pm
Friday 4th March – Available at 1pm, 3pm, 5pm and 6:30pm
Saturday 5th March – Available at 1pm, 3pm, 5pm and 6:30pm

Departures (Fiesta Americana Condesa – Cancun Airport)

Thursday 25th February – Available at 9am, 11am, 1pm and 3pm
Friday 26th February – Available at 9am, 11am, 1pm and 3pm
Sunday 28th February – Available at 9am, 11am, 1pm and 3pm
Monday 29th February – Available at 9am, 11am, 1pm and 3pm
Wednesday 2nd March – Available at 9am, 11am, 1pm and 3pm
Thursday 3rd March – Available at 9am, 11am, 1pm and 3pm
Saturday 5th March – Available at 9am, 11am, 1pm and 3pm
Sunday 6th March – Available at 9am, 11am, 1pm and 3pm
Tuesday 8th March – Available at 9am, 11am, 1pm and 3pm
Wednesday 9th March – Available at 9am, 11am, 1pm and 3pm

$25 per person, each way (includes taxes)

Please allow at least 45minutes from your flight landing time to the shuttle departure time. In the event of any delays or cancellations, please ensure you contact Tropical Incentives at least 24hours in advance; if Tropical Incentives are not informed within 24hours full cancellation charges will apply.

Upon arrival at the airport, please exit the terminal building and look for ‘Fusion Conferences’ signage where a member of Tropical Incentives team will greet you and escort you to the group transportation.

Please contact Tropical Incentives directly to enquire or make a booking.

Group booking Code: Fusion
Contact: Francisco Mora
Telephone: 998-193-3940 ext 158
Email: guestservices@ticancun.com

Private Transportation

Tropical Incentives also offer a private transfer service for those travelling outside of the available shuttle dates/times mentioned above. The private transfer service vehicles can accommodate a maximum of 6 persons, plus luggage.

$75 per vehicle, each way (includes taxes)

In the event of any delays or cancellations, please ensure you contact Tropical Incentives at least 24hours in advance; if Tropical Incentives are not informed within 24hours full cancellation charges will apply.

Upon arrival at the airport, please exit the terminal building and look for ‘Fusion Conferences’ signage where a member of Tropical Incentives team will greet you and escort you to your transportation.

Please contact Tropical Incentives directly to enquire or make a booking.

Group booking Code: Fusion
Contact: Francisco Mora
Telephone: 998-193-3940 ext 158
Email: guestservices@ticancun.com

** Please note that Fusion Conferences is not responsible for any bookings made with Tropical Incentives as transportation is not included in the registration package **

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2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Local Activities

Half Day Activities 

Tropical Incentives are a reputable and reliable company offering a variety of fascinating trips and excursions for either a half or full day. To make an enquiry please contact Francisco Mora at Tropical Incentives or alternatively, if you would like to proceed with a booking (individual/group) please follow the link below which will take you directly to an online booking facility giving details of tours available.

Contact: Francisco Mora
Email: guestservices@ticancun.com

http://www.tropicalincentives.com/form_gpos/sales/cancun/2016/fusion-conference/

Our half day tours can be booked during the conference period between the available free times scheduled in the programme. The half day tours are available to both individual and group bookings.

The following activities are available at Aquaworld which is based in the Marina directly opposite the Fiesta Americana Condesa hotel and therefore no transportation is necessary.

Aquatwister

Experience Aquaworld’s ultimate tour adventure on board a high speed jet boat ride, Aquatwister. This is a roller coaster of manoeuvres orchestrated by a highly skilled captain and drivers on board and provides an amazing combination of nature, emotion, fun and adrenaline in one adventure.

Duration: 30 minutes
Please be at the marina 30 minutes in advance of activity.
Capacity: 20 persons per boat
Price: $69.60 per person
Dock fee: $8 (cash)
Gratuity: $5

Inclusive of:
Lockers, Life jackets and bottled water

Sky Ridder

Live this exciting experience flying in couples over the Caribbean Sea and experiencing an amazing aerial view.

Duration: 30-40 minutes includes 10 minute flying time at an altitude of 100mtrs
Please be at the Aquaworld hut (located by the hotel pool) 15 minutes in advance of activity.
Capacity: Maximum 8 person per boat
Price: $63.80 per couple
Gratuity: $5

Inclusive of:
10 minutes flying time, life jackets and bottled water

*Bathing suit, towel, shorts, T-shirts, sandals or wet shoes, sunglasses and water camera recommended.
*Service charge of $5 for any lost locker keys
*Biodegradable suntan lotion is only permitted on the reef

Jungle Tour

Enjoy this fascinating adventure, driving a Jet Ski boat for 2 persons through the mangroves of Nichupte Lagoon, explore the wonders of Cancun’s jungle and the exotic wild life and admire the colourful sea life while you snorkel at one of the greatest coral reefs in Punta Nizuc.

Duration: 2:30 hrs. (45 minutes each way driving and 40 minutes for snorkelling)
Please be at the marina 30 minutes in advance of activity.
Capacity: 2 persons per boat
Price: $69.60 (Single persons would pay full boat rate)
Dock Fee and Reef tax: $11 (cash)
Gratuity: $5

Inclusive of:
1x Guide per 10 persons
Aquaray speed boat for 2 persons
Snorkel Equipment (new snorkelling gear, life vest, mask, fins)
Jungle Tour
Dressing Room, Showers and Lockers
Bottled water
TI Staff present

*Bathing suit, towel, shorts, T-shirts, sandals or wet shoes, sunglasses and water camera recommended.
*Biodegradable suntan lotion is only permitted on the reef

Wave Runner

Drive and Speed on board of a 700 Yamaha wave runner across the Caribbean Sea.

Duration: 30 minutes
Please be at the Aquaworld hut (located by the hotel pool) 15 minutes in advance of activity.
Price: $63.80 (Single persons would pay full boat rate)
Gratuity: $5

Inclusive of:
1 Guide per 10 persons
Life jackets and lockers
Bottled water

*Bathing suit, towel, shorts, T-shirts, sandals or wet shoes, sunglasses and water camera recommended.
**Biodegradable suntan lotion is only permitted on the reef**

Sub See

An extraordinary way to admire the marine life and the reef’s ecosystem without getting wet! Be part of this unique adventure on board The Sub See Explorer, a glass bottom boat like a yellow submarine with huge glass panels on the sides, from where you will be able to watch the multi-coloured species of the Scorpion´s coral reef.

Duration: 2 hrs.
Please be at the marina 30 minutes in advance of activity
Capacity: Boat can hold 66 passengers
Price: $46.40 per person
Dock Fee and Reef tax: $10
Gratuity: $5

Inclusive of:
Boat transportation on board of Reef Express
Specialized Guides
Beverages (Beer, Soft Drinks and water)
Bottled Water
TI Staff present

*Bathing suit, towel, shorts, T-shirts, sandals or wet shoes, sunglasses and water camera recommended.
**Biodegradable suntan lotion is only permitted on the reef**

Full Day Activities

To make an enquiry or booking (individual/group), please contact Francisco Mora at Tropical Incentives.

Francisco Mora
Email: guestservices@ticancun.com

A Tropical Incentive representative will also be available during the conference period at the hotel, so should you have any questions about a booked tour you can always ask upon arrival or at any time during your stay.

Our full day tours are offered pre and post conference dates. If you require any additional nights at the Fiesta Americana Condesa due to a full day excursion, please ensure you book these in advance to avoid disappointment. The full days tours are available to both individual and group bookings.

Tulum And Playa Del Carmen Shopping Tour

Our journey begins in the magical ancient Tulum Archaeological Zone, discovered by John L. Stephens in 1842. Perched on top of a cliff facing the Caribbean Sea, it is the only entire walled in-group of Mayan Ruins ever discovered. Under the advice of an official English speaking tour guide, the group will go around the structures getting the history and spirit of the Mayans. Afterwards we head Playa del Carmen, an authentic Mexican town, popular because of its beautiful beaches with turquoise water colour and the famous 5th Avenue where the participants will browse around the shops aside to explore. All kind of typical items, handcrafts, pottery, typical rugs most of them hand made by top artisans, fine boutiques selling everything imaginable. A unique experience! A group lunch can be arranged in one of the restaurants or it can be at leisure.

Ek Balam and Cenote

Visit the archaeological site of Ek-Balam. Ek Balam means Bright Star Jaguar in Maya language. This ancient Maya city had its glory before Chichen Itza. This archaeological site is one of the latest attractions because of its most recent restoration. Discover the mysterious Maya Cenote, enjoy its beautiful natural formations and great natural pool of 80m diameter. During the tour you will see different Maya communities. Take home your memories with the beautiful photographs taken by native photographers during the activities.

Sea Passion Catamaran

Isla Mujeres (Island of Women) is one of the Mexican Caribbean’s favourite destinations. Sail the beautiful turquoise bay from Cancun to Isla Mujeres aboard the Sea Passion I or Sea Passion III, a one-of-a-kind 75 & 60 foot maxi-catamarans, designed for passenger comfort. Enjoy a sail and snorkelling in the National Marine Park. Relax. In the full day activity the participants will have the opportunity to disembark in the Island. You can enjoy exquisite dining at the Beach Club “ElPescador” and the overwhelming views of the turquoise ocean decorated by coconut palm trees and hammocks.

Selvatica Extreme Canopy Tour

Located between Cancun and Playa del Carmen, only 35 minutes form Cancun’s International Airport. Over 250 acres of Tropical Jungle, in Selvatica you will be able to experience a unique adventure in the longest zip-line circuit  in North America, recognized by Travel & Leisure magazine as one of the 35 great adventures in the World, divided in 12 zip lines varying in lengths and heights from 270 ft. to over 2,000 ft, it will make you fly over the jungle. Take a ride on a military vehicle through the jungle to get to the millenary natural cenote. With crystal and pristine waters you will be able to swim choosing between a water zip line or the diving platform. Live this unique and exciting adventure and feel the emotion and adrenaline running through your body.

Coba

Deep in the heart of the Quintana Roo jungle and only 24 miles from southwest of Tulum, approximately 2 1/2 south of Cancun is COBA, an archaeological site that dates from the Classis period. Unlike other Mayan sites in Quintana Roo, Coba was still occupied after the Spanish Conquest. 
This incredible Site once occupied an area of almost 100 square kilometers (60 st. miles). The pyramid of Nohoch Mul-43 meters (130  ft.) high-is the tallest pre-Hispanic structure in the Yucatan peninsula. The main pyramids are the Coba Group, near the entrance, Las Pinturas (The Paintings), named because of the colour still visible on the arches; the Macanxoc, located next to Macanxoc Lake; and Chumuc Mul, the main stucco pyramid which still contains its original colour. 
After a very cultural tour, be prepared to enjoy a delicious lunch in one of the magic restaurants of the area.

For further details on the above and other tours available please contact Tropical Incentives where Francisco Mora or an alternative representative will be happy to assist you.

Contact: Francisco Mora
Email: guestservices@ticancun.com

Supported By

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If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Group Activities

Chichen-Itzá Group Tour - Friday 26th February 2016

We have arranged an exciting private group tour for all 2016 DDRC participants. The tour will take place the day immediately following the conference on Friday 26th February 2016.

Chichen-Itzá, recently nominated one of the new 7th wonders is  the ancient city whose name means "in the mouth at the Itzáe's Well", was in its time of grandeur (between 800 and 1200 A.D.), the centre of political, religious and military power in Yucatán, if not all of South-eastern Meso America. Chichen-Itzá is located 125 miles West of Cancun about 2:15 hrs. It is the most visited archaeological site on the Peninsula, famed for its extraordinary architectural beauty. When the Spaniards arrived in Chichen-Itzá, it had long been abandoned, a victim of the Mayapan wars. Somewhere between 1196 and 1441 the May culture collapsed on the northern shores of the peninsula. The conqueror found the buildings in ruins; their names and uses lost to time. Present names and uses are intelligent guesses.

The tour is optional and should you wish to participate we would ask that you email laura@fusion-conferences.com to confirm your participation no later than Monday 15th February as we are required to confirm numbers in advance due to transportation requirements.

Itinerary for Friday 26th February 2016:

08.15 – Meeting Point in Lobby
08.30 – Departure from Hotel
11:00 – Arrival at Chichen-Itzá
11:15 – 13:00 – Guided Visit to the Archaeological Site
13:15 – Departure from Chichen-Itzá to Restaurant
13:30 – 14:30 – Lunch
14:45 – Return to Transportation
17:30 – Estimated Return to Hotel

The price of the tour will vary depending on confirmed numbers. We will confirm the tour price during conference registration. For guidance, please note the following prices dependent on final group size.

$155.00 – Requires 6 participants
$115.00 – Requires 10+ participants
*Please consider an additional $5.00 gratuity, per person.

The above prices include; air conditioned transportation, 2 beverages on board (soft drinks and/or water), tour guide, admission fees at Chichen-Itzá, buffet lunch (food only) and federal tax. Please note the above prices exclude; food and beverages inside the ruins and beverages during lunch.

Please note that payment for the tour will need to be made during conference registration at the Tropical Incentives Hospitality desk. Tropical Incentives will accept both cash and card payments. Please note a surcharge will be added for payments made using card (5% for VISA or Master Card and 6% for AMEX). This is a non-refundable fee should you later change your mind and decide not participate in the tour.

Supported By

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If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Childcare

Supported By

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If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Oral Presenters

We have a number of oral opportunities available at this meeting. To be considered for a talk, please register for the conference and you will be able to submit your abstract online and monitor the status of your abstract through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Please take note of the oral submission deadline: 14 September 2015

Please check the conference programme carefully to note your presentation time (inclusive of Q&A) should you be accepted for an oral presentation. We recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference page.

Your Presentation on the Day

If you have prepared some slides to accompanying your talk please ensure you bring these with you on a USB or portable file saving device.

For those presenting on the first day, please email your slides to us so we can have everything prepared and ready for the first session. Please email your slides to: admin@fusion-conferences.com

On the day of your presentation please make yourself known to the AV team who will be available in the conference room. If you have any animations or videos we do advise to run through the presentation with the AV tech to make sure everything is compatible. We also advise that all speakers make themselves known to the AV tech in the conference room immediately before your session beings. The AV tech will apply your microphone and provide a laser pointer should you have an accompanying presentation. We prefer speakers to use our master laptop to run presentations from, however, if you prefer to use your own laptop, please notify us in advance.

It is important that all speakers adhere to their presentation time and respect their fellow presenters. A visual traffic light aide will be available to warn presenters and the audience as your time decreases.

If you have any questions, please don’t hesitate to approach our AV tech or a member of the Fusion team.

Helpful Tips for Presentation Slides

Aspect Ratio: 4:3 in Presenter View, Landscape in Orientation
Font Size: Minimum font size used should be 24pt. 
File Type: Please safe your presentation in PPT or PPTS format. 
Video Clips: Please save these separately and do not build them into the PowerPoint. Videos will be played via the AV control desk using the master laptop.

Download Abstract Template

Supported By

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If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Posters

We have a number of poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and you will be able to submit your abstract online and monitor the status of your abstract through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Please take note of the poster submission deadline: 05 January 2016

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

During conference registration if you are presenting a poster please request a poster number from the registration desk. Please do not put up your poster without notifying a member of the Fusion team. Certain adhesive agents are not permitted at some venues therefore; Fusion will be the sole provider of all poster fixings.

You can display your poster from registration. Your poster can remain on display for the entire duration of the conference and we ask that posters are taken down on the final day of the meeting. The poster session is usually scheduled on Day 3, but please check the official programme for exact timings. Refreshments will be provided and the poster prizes will be awarded during the conference Gala Night that evening. 

2016 DDRC Poster Prize

The conference chairs will be awarding five exceptional poster prizes for the best poster display and presentation. To be in with a chance of winning, submit your poster by 26 January 2016. The winners will be selected shortly after the Poster Session and the following prizes/travel grants will be awarded. 1st Place $400, 2nd Place $400, 3rd Place $350, 4th Place $250 and 5th Place $150.

In addition to the monetary prize provided by Fusion, F1000 have kindly provided the following prizes for all five winners.

1) A personalised F1000 Poster Prize certificate.
2) A free personal subscription to F1000 allowing access to all recommendations and our new collaborative authoring tool.
3) A free article submission to F1000Research worth up to $1,000.

Download Abstract Template

Supported By

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If you're interested in sponsoring this conference please contact us.

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

22 Feb 2016 - 25 Feb 2016

Cancun, Mexico

Chairs

Conference History

12 Feb 2014, 15 Feb 2014

Dynamic Structures in DNA Damage Responses and Cancer

Fiesta Americana Condesa, Cancun, Mexico

Key sessions will include: DNA and RNA complexes Chromatin Remodeling Post-translational modifications - Ub, SUMO kinases The repair interface with Replication Transcription, and Recomb...

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22 Feb 2016, 25 Feb 2016

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

Fiesta Americana Condesa, Cancun, Mexico

This conference will focus on insights into dynamic DNA and RNA complexes involved in the damage response and cancer. It will emphasize informal as well as formal discussions together with informative talks and...

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11 Feb 2018, 15 Feb 2018

3rd DNA Replication/Repair Structures and Cancer Conference

Fiesta Americana Condesa, Cancun, Mexico

The remarkable stability of the human genome is lost in cancer cells due to the failure of efficient and accurate repair in the context of oncogene-induced replication stress and elevated transcription. DNA replication is furthermore emerging as a...

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16 Feb 2020, 20 Feb 2020

4th DNA Repair/Replication Structures and Cancer Conference

Melia Nassau Beach All Inclusive, Nassau, Bahamas

The remarkable stability of the human genome is lost in cancer cells due to the failure of efficient and accurate DNA repair in the context of oncogene-induced replication stress and elevated transcription. Intertwined roles of repair with replica...

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Supported By

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Media Partners
If you're interested in sponsoring this conference please contact us.