Registration deadlines

Early Bird - Expired

Talk Submission - Expired

Poster Submission - Expired

Registration Deadline - Expired

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Report

This new major conference on Target DNA repair for Cancer Therapy took place in Cancun, Mexico from 12 to 15 February 2015. The significance of this meeting was marked by euthasitic attendees from many leaders in the field of DNA damage repair pathways who are interested in identifying new targets and strategies for improving cancer therapy by targeting distinct DNA repair pathways.

The meeting was chaired by Dr. Helen Piwnica-Worms (Vice Provost, Science, The University of Texas MD Anderson Cancer Center) and Dr. Junjie Chen (Professor and Chain, Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center).

Faculty included Dr. Giulio Draetta (The University of Texas MD Anderson Cancer Center), Dr. Maria Jasin (Memorial Sloan Kettering Cancer Center), Dr. Andre Nussenzweig (National Cancer Institute), Professor John Tainer (Scripps Research Institute), Prof. Chris Bakkenist (University of Pittsburgh School of Medicine), Dr. Eric Brown (University of Pennsylvania School of Medicine), Dr. Phil Connell (The University of Chicago Medicine), Dr. David Ferguson (University of Michiga), Dr. Susana Gonzalo (Saint Louis University), Dr. Roger Greenberg (Abramson Family Cancer Research Institute), Professor Wolf-Dietrich Heyer (University of California), Dr. Karen Knudsen (Kimmel Cancer Center), Dr. Kyle Miller (University of Texas Austin), Dr. Jac A. Nickoloff (Colorado State University), Professor Jeffrey Parvin (Ohio State University), Dr. Tanya Paull (The University of Texas at Austin), Dr. Bill Plunkett (The University of Texas MD Anderson Cancer Center), Dr. Simon Powell (Memorial Sloan Kettering Cancer Center), Dr. Jorge S. Reis-Filho (Memorial Sloan Kettering Cancer Center), Dr. Binghui Shen (City of Hope), Dr. Barry Sleckman (Washington University, School of Medicine< Dr. Robert Sobol (University of Pittsburgh), Dr. Henning Willers (Massachusetts General Hospital), Dr. Zhongshen You (University of Washington), Dr. Xiaochun Yu (University of Michigan), and Dr. Lee Zou (Harvard/MGH Cancer Center)

The meeting highlighted several exciting areas in the field of DNA damage response, which include 1) repair pathway choices and therapeutics outcomes, 2) new therapeutic targets in DNA repair, 3) ongoing clinical trials targeting DNA repair pathways and DNA damage checkpoints. Exciting presentations from basic scientists, clinicians and translational experts presented multitude of new strategies for cancer therapy, which range from concepts, leading compounds, to early clinical trials. The meeting was highly interactive and generated healthy discussions about current and future directions of the field. Novel ideas were exchanged and collaborations were established, which focus on distinct repair pathways and components involved in DNA double strand breaks, novel functions of repair proteins, checkpoint regulators, and chromatin modulators, and key signaling pathways and kinases that are existing and potential targets for cancer therapy.

The participation of internationally renowned leaders in the field of DNA damage response together with the excitement of new drugs like PARP inhibitors and checkpoint kinase inhibitors that hold great promise in clinical trials created a supportive meeting environment. The investigators were eager to work together to address several key questions in the field. It was agreed that the timing is right for a conference like this that helps to accelerate the development of new concepts and agents in DNA repair for cancer treatment.  

_____________________________________

The meeting was expertly organized and supported by Fusion Conferences, Ltd.  The University of Texas MD Anderson Cancer Center generously and enthusiastically supported the meeting in many ways and the generous support of Cell Signaling Technology is also gratefully appreciated.

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Synopsis

The first in the series of the Exploring DNA Repair Pathways as Targets for Cancer Therapy Fusion conferences. 

Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows the accumulation of multiple genetic alternations, which are essential for the initiation of tumorigenesis. This has been clearly illustrated to be the cause of several human cancer-prone syndromes and also revealed by recent human genome studies. On the other hand, defective DNA repair and checkpoint activation also make cancer cells more vulnerable for particular DNA damaging agents or inhibitors that specifically disrupt some of these checkpoint pathways. With the increasing understanding of defects in DNA repair and checkpoint control in tumorigenesis, there are extensive interests in exploring these deficiencies, especially taking advantage of the synthetic lethality concept and targeting particular DNA repair and checkpoint pathways for cancer therapy. The purpose of this conference is to bring together basic, translational and clinical investigators and discuss the current and future directions, opportunities and obstacles in the development of these anti-cancer modalities and how to best apply these concepts in clinical practice.

Key Sessions

  • Highlight recent advances in the field of DNA damage repair
  • Identify novel targets in DNA repair and checkpoint pathways
  • Explore the concept of synthetic lethality for cancer treatment
  • Assess the therapeutic potential of new anti-cancer modalities
  • Learn mechanisms of therapeutic resistance and ways to improve cancer therapy

Target Audience

This conference explores topics that should appeal to basic, translational and clinical investigators as well as clinicians ranging from academics to industry. The audience will benefit greatly from the interactions with experts in the fields of DNA damage response, drug development and clinical trials.

2015 DNA Poster Prize

The conference chairs will be awarding 3 poster prizes for the best poster display and presentation. To be in with a chance of winning, submit your poster by 21 November 2014. The winners will be selected shortly after the Poster Session and each winner will receive a $250 cheque! 

Confirmed Plenary Speakers

Dr. Giulio Draetta
The University of Texas MD Anderson Cancer Center
Professor Thomas Helleday
Karolinska Institutet
Dr. Maria Jasin
Memorial Sloan Kettering Cancer Center
Dr. Andre Nussenzweig
National Cancer Institute
Professor John Tainer
Scripps Research Institute 

Confirmed Invited Speakers

Prof. Chris Bakkenist
University of Pittsburgh School of Medicine
Dr. Eric Brown
University of Pennsylvania School of Medicine
Dr. Phil Connell
The University of Chicago Medicine
Dr. David Ferguson 
University of Michigan
Dr. Susana Gonzalo 
Saint Louis University
Dr. Roger Greenberg
Abramson Family Cancer Research Institute 
Professor Reuben Harris
University of Minnesota
Professor Wolf-Dietrich Heyer
University of California 
Dr. Karen Knudsen
Kimmel Cancer Center
Dr. Kyle Miller 
University of Texas Austin
Dr. Jac A. Nickoloff 
Colorado State University
Professor Jeffrey Parvin 
Ohio State University
Dr. Tanya Paull
The University of Texas at Austin
Dr. Bill Plunkett
The University of Texas MD Anderson Cancer Center
Dr. Simon Powell
Memorial Sloan Kettering Cancer Center
Dr. Jorge S. Reis-Filho
Memorial Sloan Kettering Cancer Center
Dr. Binghui Shen
City of Hope
Dr. Barry Sleckman
Washington University - School of Medicine
Dr. Robert Sobol
University of Pittsburgh
Dr. Henning Willers
Massachusetts General Hospital
Dr. Zhongshen You
University of Washington
Dr. Xiaochun Yu
University of Michigan
Dr. Lee Zou
Harvard/MGH Cancer Center 

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Speakers

Plenary Speakers

Invited Speakers

Christopher Bakkenist

Associate Professor, University of Pittsburgh School of Medicine

Bill Plunkett

Professor, Univ.of Texas MD Anderson Cancer Center

Jean Gautier

Professor, Columbia University Medical Center

Ralph Scully

Associate Professor, Beth Israel Deaconess Medical Center

Lee Zou

Professor, Massachusetts General Hospital

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Programme

Thursday 12th February 2015

12:00 – 15:00

Registration

13:00 -14:15

Welcome Lunch
*Kalmia Buffet Restaurant
*

Repair pathway choices and therapeutic outcomes (1)
Session Chair:  Roger Greenberg

15:30 – 15:45

Opening Speech

15:45 – 16:30

Andre Nussenzweig

National Institutes of Health

TUMOR PROMOTING ROLE OF THE DNA DAMAGE RESPONSE

16:30 – 17:00

Barry Sleckman
Washington University School of Medicine

TARGETING ABERRANT DNA DOUBLE STRAND BREAK REPAIR IN G1-PHASE CELLS

17:00 – 17:30

David Ferguson
The University of Michigan

THE MRN COMPLEX AS A POTENTIAL TARGET FOR CANCER THERAPY

17:30 – 18:00

Refreshments

Repair pathway choices and therapeutic outcomes (2)
Session Chair:  Barry Sleckman

18:00 – 18:30

Simon Powell
Memorial Sloan Kettering Cancer Center

BACK-UP PATHWAYS FOR BRCA1-BRCA2 MEDIATED HOMOLOGOUS RECOMBINATION

18:30 – 19:00

Junjie Chen
The University of Texas MD Anderson Cancer Center

MULTIPLE REPAIR PATHWAYS DETERMINE THERAPEUTIC OUTCOMES

19:00 – 19:30

Roger Greenberg
University of Pennsylvania

GENETIC INTERACTIONS WITHIN THE BRCA TUMOR SUPPRESSOR NETWORK

19:30 – 20:00

Ralph Scully
Beth Israel Deaconess Med Ctr

RECOMBINATION CONTROL BY BRCA1 AND BRCA2 AT STALLED MAMMALIAN REPLICATION FORKS: OPPORTUNITIES FOR THERAPY

20:00 – 20:15

Richard Pomerantz
Temple University

TARGETED KILLING OF BRCA DEFICIENT CELLS BY A SMALL-MOLECULE INHIBITOR OF RAD52

20:15 – 20:30

Panel Discussion PM

20:30

Dinner at Leisure & Free Time

Friday 13th February 2015

07:00 -08:30

Breakfast

Emerging therapeutic targets and clinical trials for cancer therapy
Session Chair: Karen Knudsen

08:30 – 09:15

Thomas Helleday
Karolinska Institutet

TARGETING MTH1 FOR TREATMENT OF CANCER

 

09:15 – 09:45

Wolf-Dietrich Heyer
University of California, Davis

RECOMBINATIONAL DNA REPAIR: FROM BASIC MECHANISM TO CANCER THERAPY

09:45 – 10:15

Philip Connell
University of Chicago

DEVELOPMENT OF RAD51-MODULATING COMPOUNDS AS POTENTIAL ONCOLOGY DRUGS

10:15 – 10:45

Robert W. Sobol
University of South Alabama Mitchell Cancer Institute

TARGETING ADP-RIBOSYLATION PROTEINS IN GLIOMA STEM CELLS

10:45 -11:00

Kent W Mouw

Dana-Farber Cancer Institute

ERCC2 MUTATIONS CONFER LOSS OF NUCLEOTIDE EXCISION REPAIR CAPACITY AND PREDICT RESPONSE TO CISPLATIN-BASED CHEMOTHERAPY IN UROTHELIAL CARCINOMA

11:00 – 11:15

Refreshments

11:15 – 11:45

Jorge Reis-Filho
Memorial Sloan-Kettering Cancer Center

 

11:45 – 12:15

Henning Willers
Massachusetts General Hospital

TARGETING DNA DOUBLE-STRAND BREAK INDUCTION AND REPAIR IN
GENOTYPE-DEFINED CANCERS

12:15 – 12:30

Bernd Kaina
University Medical Center, Mainz

SURVIVAL AND DEATH STRATEGIES OF GLIOMA AND MALIGNANT MELANOMA CELLS EXPOSED TO ALKYLATING ANTICANCER DRUGS

12:30 – 12:45

Panel Discussion AM

12:45 – 16:00

Lunch at Leisure & Free Time

Multiple targets and cellular processes involved in cancer development and treatment
Session Chair: Markus Löbrich

16:00 – 16:30

Tanya Paull
The University of Texas at Austin

REGULATION OF SAE2 AND CTIP ACTIVITY THROUGH PHOSPHORYLATION

 

16:30 – 17:00

Binghui Shen
Beckman Research Institute of City of Hope

ALPHA-SEGMENT ERROR EDITING BY THE MAMMALIAN FEN1/MUTSΑ FUNCTIONAL COMPLEX

 

17:00 – 17:15

Katharina Schlacher
MD Anderson Cancer Center

RECRUITMENT OF 53BP1 FOR REPLICATION FORK RESTART AND STABILITY DEPENDS UPON A PHOSPHATASE-INDEPENDENT PTEN ACTIVITY

17:15 – 17:30

Gregory C. Stachelek
Yale University School of Medicine

ARYL SULFONAMIDES ARE A NOVEL CLASS OF HOMOLOGY-DEPENDENT DNA REPAIR INHIBITORS WITH ANTINEOPLASTIC ACTIVITY

17:30 – 18:00

Susana Gonzalo
Saint Louis University School of Medicine

VITAMIN D RECEPTOR MODULATES DNA REPAIR: IMPLICATIONS FOR BREAST CANCER AND PROGERIA

18:00 – 18:30

Refreshments

18:30 – 19:15

Giulio Draetta
The University of Texas MD Anderson Cancer Center

 

19:15 – 19:45

Kyle Miller
University of Texas at Ausin

ATM LINKS ENDOGENOUS OXIDATIVE STRESS TO TUMOR PROMOTION

19:45 – 20:00

Srividya Bhaskara
Huntsman Cancer Institute

HISTONE DEACETYLASES 1,2: GUARDIANS OF GENOME STABILITY

 

20:00 – 20:15

Sergio Ruiz

CNIO

REPLICATIVE STRESS DURING SOMATIC CELL REPROGRAMMING

20:15 – 20:30

Panel Discussion PM

20:30

Dinner at Leisure & Free Time

Saturday 14th February 2015

07:00 – 08:30

Breakfast

Current and potential therapeutic targets in DNA repair pathways
Session Chair: Wolf-Dietrich Heyer

08:30 – 09:15

John Tainer
Lawrence Berkeley National Laboratory

ZEROING IN ON MASTER KEYS TO EXCEPTIONAL RESPONDERS FOR CANCERS

09:15 – 09:45

Jean Gautier
Columbia University

Mechanisms of MYC-driven genomic instability

09:45 – 10:00

Bipasha Mukherjee
UT Southwestern Medical Center at Dallas

Inhibition of DNA Double-Strand Break Repair by A Dual PI3K/mTOR Inhibitor as a Strategy for Radiosensitization of Glioblastoma

 

10:00 – 10:30

Zhongsheng You
Washington University School of Medicine

COORDINATED REGULATION OF EXO1 IN DNA END RESECTION AND ITS IMPLICATIONS IN CANCER THERAPY

10:30 – 10:45

Anand Jeyasekharan

Cancer Science Institute of Singapore

BRCA2-RAD51 NUCLEAR EXPORT; FROM MOLECULAR MECHANISM TO A BIOMARKER OF HOMOLOGOUS RECOMBINATION DEFICIENCY

10:45 – 11:00

Sharon Cantor
University of Massachusetts Medical School

A NOVEL MECHANISM OF THERAPY RESISTANCE IN BRCA2-MUTANT CELLS

11:00 – 11:30

Refreshments

11:30 – 12:00

Karen Knudsen
Thomas Jefferson University

TARGETING HORMONE-DNA REPAIR CROSSTALK IN PROSTATE CANCER: MECHANISMS AND IMPLICATIONS FOR THERAPEUTIC INTERVENTION

12:00 – 12:30

Bill Plunkett
The University of Texas MD Anderson Cancer Center

MECHANISM-BASED THERAPEUTIC STRATEGY TO TARGET A RECURRENT GENETIC LESION IN THE HOMOLOGOUS RECOMBINATION REPAIR PATHWAY

12:30 – 12:45

Panel Discussion

12:45 – 16:30

Lunch at Leisure & Free Time

Checkpoint kinases as therapeutic targets
Session Chair: Xiaochun Yu

16:30 – 17:00

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center

DNA DAMAGE, CHECKPOINT SIGNALING AND THERAPEUTIC OPPORTUNITIES

17:00 – 17:30

Eric Brown
University of Pennsylvania

ATR INHIBITION AS A BROAD SPECTRM CANCER THERAPY TARGETED BY COMMON CANCER-ASSOCIATED MUTATIONS

17:30 – 18:00

Lee Zou
Massachusetts General Hospital

ALTERNATIVE LENGTHENING OF TELOMERES RENDERS CANCER CELLS HYPERSENSITIVE TO ATR INHIBITORS

18:00 – 18:15

Xuetong Shen
The University of Texas MD Anderson Cancer Center

REGULATION OF KEY CHECKPOINT KINASES BY ATP-DEPENDENT CHROMATIN REMODELING COMPLEXES – NOVEL PATHWAYS TO TARGET IN CANCER

 

18:15 – 18:45

Christopher Bakkenist
University of Pittsburgh School of Medicine

INHIBITION OF ATR KINASE ACTIVITY FOR THE TREATMENT OF LUNG CANCER

18:45 – 19:00

Panel Discussion

19:00 – 20:00

Poster Session & Cocktails

20:15 – 23:00

Gala Night, Group Photo & Poster Awards

*Lower Pool Deck*

Sunday 15th February 2015

07:00 -08:30

Breakfast

DNA double-strand repair pathways in response to anti-cancer therapies (1)
Session Chair: Sharon Cantor

08:30 – 09:15

Maria Jasin
Memorial Sloan-Kettering Cancer Center

 

09:15 -09:45

Xiaochun Yu
University of Michigan

NOVEL POLY(ADP-RIBOSE) BINDING DOMAINS AND POLY(ADP-RIBOSE)-DEPENDENT SIGNAL TRANSDUCTION

09:45 – 10:15

Jeffrey Parvin
Ohio State University

BRCA1, 53BP1, AND SUMO FACTORS IN DNA DOUBLE-STRAND BREAK REPAIR

10:15 – 10:45

Jac Nickoloff
Colorado State University

METNASE AND EEPD1:  TWO NUCLEASES THAT REGULATE DSB REPAIR, REPLICATION STRESS RESPONSES AND GENOME STABILITY

 

10:45 – 11:15

Refreshments

DNA double-strand repair pathways in response to anti-cancer therapies (2)
Session Chair: Jeffrey Parvin

11:15 – 11:30

Junran Zhang
Case Western Reserve University

RNF126 PROMOTES HOMOLOGOUS RECOMBINATION VIA REGULATING E2F1-MEDIATED BRCA1 EXPRESSION

11:30 – 11:45

Markus Löbrich
Darmstadt University of Technology

NEK1 PHOSPHORYLATES RAD54 TO PROMOTE HOMOLOGOUS RECOMBINATION

11:45 – 12:00

Tomasz Skorski

Temple University School of Medicine

GENE EXPRESSION AND MUTATION ANALYSIS (GEMA) –GUIDED PRECISION MEDICINE TARGETING PARP1 TO INDUCE SYNTHETIC LETHALITY IN DNA-PK –DEFICIENT QUIESCENT AND BRCA -DEFICIENT PROLIFERATING LEUKEMIA STEM AND PROGENITOR CELLS

12:00 – 12:15

Panel Discussion

12:15 – 12:30

Closing Remarks


Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Prices

Early Bird Full Price Additional Adult Additional Child Extra Night Adult Extra Night Child
Academic $1444 $1564 $699 $225 $250 $75
Industry $1444 $1564 $699 $225 $250 $75
Student $1265 $1385 $699 $225 $250 $75

All registration fees include 3 nights accomodation and meals during the conference period. Exact inclusions are detailed below.

Our Registration Package: What's Included?

The Fiesta Americana Condesa, Cancun offers a Full Meal Plan to all attendees. Our registration and accompanying person fees are inclusive of the following;

  • Accommodation for 3 Nights
  • Breakfast, Lunch and Dinner – available at all restaurants according to operational hours or programmed events.
  • International Bar available by the glass in restaurants and bars according to operational hours.
  • Pool snacks and International Bar available by the glass at Pool Area
  • Minibar including: soft drinks, domestic beer, bottled water and coffee. Refreshed daily
  • 24 Hour Room Service
  • In Room amenity – Bottle of wine, per room, per stay
  • Complimentary WI-FI in Conference Room
  • Complimentary WI-FI in Guest Room
  • Gala Night Entry (includes an open bar)

Please note: Accompanying persons are not permitted access to the conference.

Additional nights (per person) are inclusive of the following;

  • Accommodation for 1 Night
  • Lunch on day of arrival
  • Dinner on day of arrival
  • Breakfast on day of departure
  • International bar available by the glass in restaurants and bars from lunch on day of arrival until breakfast on day of departure.

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Venue

Fiesta Americana Condesa

Venue Rating
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa, Blvd.Kukulkán km 16.5 Zona Hotelera, Cancun, 77500 Mexico
Nearest Airport
Cancun International Airport

This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment.  We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

  • Lagoon Pool
  • Extensive Health Club and Spa
  • Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas

The Fiesta Americana Condesa, Cancun is the 2015 Winner of the Trip Advisor Certificate of Excellence and also received the Travellers Choice Award in 2014. 

The remains of ancient Mayan cities are scattered throughout the Yucatan Peninsula and no trip to Cancun would be complete without a visit to these majestic temples and pyramids set amongst lush tropical vegetation. We will be working very closely with a reputable tour company who will be organising trips to Tulum, Chichen Itza, Coba and Xcaret  to name a few, some of which may require a full day. Full day excursions will be arranged pre or post conference and may be on an individual or group booking so we would recommend booking extra nights to extend your stay as early as possible to avoid disappointment should these excursions be of interest to you and/or your party. For further information please contact us.

Location

Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.

Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Transportation

Travel Details

Cancun International airport is just a short 15 minute journey from the Fiesta Americana Condesa and is easily accessible from almost every country in the world with many major international airlines providing direct or interconnecting flights on a daily basis. 

Airport Transfers

Tropical Incentives are a reputable and trustworthy DMC based in Cancun. The Tropical Incentives team will be on hand to provide a seamless transfer service to and from Cancun International Airport. Tropical Incentives will manage and confirm all transportation bookings. To arrange transportation please contact Tropical Incentives directly via email, phone or the online booking facility (see link below).  

http://www.tropicalincentives.com/form_gpos/sales/cancun/2016/fusion-conference/

Conference Shuttle Service

Tropical Incentives have arranged a conference shuttle service which will run at scheduled times surrounding the conference. The conference shuttle schedule can be found below.

Arrivals (Cancun Airport – Fiesta Americana Condesa)

Sunday 21st February – Available at 1pm, 3pm, 5pm and 6:30pm
Monday 22nd February – Available at 1pm, 3pm, 5pm and 6:30pm
Wednesday 24th February – Available at 1pm, 3pm, 5pm and 6:30pm
Thursday 25th February – Available at 1pm, 3pm, 5pm and 6:30pm
Saturday 27th February – Available at 1pm, 3pm, 5pm and 6:30pm
Sunday 28th February – Available at 1pm, 3pm, 5pm and 6:30pm
Tuesday 1st March – Available at 1pm, 3pm, 5pm and 6:30pm
Wednesday 2nd March – Available at 1pm, 3pm, 5pm and 6:30pm
Friday 4th March – Available at 1pm, 3pm, 5pm and 6:30pm
Saturday 5th March – Available at 1pm, 3pm, 5pm and 6:30pm

Departures (Fiesta Americana Condesa – Cancun Airport)

Thursday 25th February – Available at 9am, 11am, 1pm and 3pm
Friday 26th February – Available at 9am, 11am, 1pm and 3pm
Sunday 28th February – Available at 9am, 11am, 1pm and 3pm
Monday 29th February – Available at 9am, 11am, 1pm and 3pm
Wednesday 2nd March – Available at 9am, 11am, 1pm and 3pm
Thursday 3rd March – Available at 9am, 11am, 1pm and 3pm
Saturday 5th March – Available at 9am, 11am, 1pm and 3pm
Sunday 6th March – Available at 9am, 11am, 1pm and 3pm
Tuesday 8th March – Available at 9am, 11am, 1pm and 3pm
Wednesday 9th March – Available at 9am, 11am, 1pm and 3pm

$25 per person, each way (includes taxes)

Please allow at least 45minutes from your flight landing time to the shuttle departure time. In the event of any delays or cancellations, please ensure you contact Tropical Incentives at least 24hours in advance; if Tropical Incentives are not informed within 24hours full cancellation charges will apply.

Upon arrival at the airport, please exit the terminal building and look for ‘Fusion Conferences’ signage where a member of Tropical Incentives team will greet you and escort you to the group transportation.

Please contact Tropical Incentives directly to enquire or make a booking.

Group booking Code: Fusion
Contact: Francisco Mora
Telephone: 998-193-3940 ext 158
Email: guestservices@ticancun.com

Private Transportation

Tropical Incentives also offer a private transfer service for those travelling outside of the available shuttle dates/times mentioned above. The private transfer service vehicles can accommodate a maximum of 6 persons, plus luggage.

$75 per vehicle, each way (includes taxes)

In the event of any delays or cancellations, please ensure you contact Tropical Incentives at least 24hours in advance; if Tropical Incentives are not informed within 24hours full cancellation charges will apply.

Upon arrival at the airport, please exit the terminal building and look for ‘Fusion Conferences’ signage where a member of Tropical Incentives team will greet you and escort you to your transportation.

Please contact Tropical Incentives directly to enquire or make a booking.

Group booking Code: Fusion
Contact: Francisco Mora
Telephone: 998-193-3940 ext 158
Email: guestservices@ticancun.com

** Please note that Fusion Conferences is not responsible for any bookings made with Tropical Incentives as transportation is not included in the registration package **

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Local Activities

Half Day Activities 

Tropical Incentives are a reputable and reliable company offering a variety of fascinating trips and excursions for either a half or full day. To make an enquiry please contact Francisco Mora at Tropical Incentives or alternatively, if you would like to proceed with a booking (individual/group) please follow the link below which will take you directly to an online booking facility giving details of tours available.

Contact: Francisco Mora
Email: guestservices@ticancun.com

http://www.tropicalincentives.com/form_gpos/sales/cancun/2016/fusion-conference/

Our half day tours can be booked during the conference period between the available free times scheduled in the programme. The half day tours are available to both individual and group bookings.

The following activities are available at Aquaworld which is based in the Marina directly opposite the Fiesta Americana Condesa hotel and therefore no transportation is necessary.

Aquatwister

Experience Aquaworld’s ultimate tour adventure on board a high speed jet boat ride, Aquatwister. This is a roller coaster of manoeuvres orchestrated by a highly skilled captain and drivers on board and provides an amazing combination of nature, emotion, fun and adrenaline in one adventure.

Duration: 30 minutes
Please be at the marina 30 minutes in advance of activity.
Capacity: 20 persons per boat
Price: $69.60 per person
Dock fee: $8 (cash)
Gratuity: $5

Inclusive of:
Lockers, Life jackets and bottled water

Sky Ridder

Live this exciting experience flying in couples over the Caribbean Sea and experiencing an amazing aerial view.

Duration: 30-40 minutes includes 10 minute flying time at an altitude of 100mtrs
Please be at the Aquaworld hut (located by the hotel pool) 15 minutes in advance of activity.
Capacity: Maximum 8 person per boat
Price: $63.80 per couple
Gratuity: $5

Inclusive of:
10 minutes flying time, life jackets and bottled water

*Bathing suit, towel, shorts, T-shirts, sandals or wet shoes, sunglasses and water camera recommended.
*Service charge of $5 for any lost locker keys
*Biodegradable suntan lotion is only permitted on the reef

Jungle Tour

Enjoy this fascinating adventure, driving a Jet Ski boat for 2 persons through the mangroves of Nichupte Lagoon, explore the wonders of Cancun’s jungle and the exotic wild life and admire the colourful sea life while you snorkel at one of the greatest coral reefs in Punta Nizuc.

Duration: 2:30 hrs. (45 minutes each way driving and 40 minutes for snorkelling)
Please be at the marina 30 minutes in advance of activity.
Capacity: 2 persons per boat
Price: $69.60 (Single persons would pay full boat rate)
Dock Fee and Reef tax: $11 (cash)
Gratuity: $5

Inclusive of:
1x Guide per 10 persons
Aquaray speed boat for 2 persons
Snorkel Equipment (new snorkelling gear, life vest, mask, fins)
Jungle Tour
Dressing Room, Showers and Lockers
Bottled water
TI Staff present

*Bathing suit, towel, shorts, T-shirts, sandals or wet shoes, sunglasses and water camera recommended.
*Biodegradable suntan lotion is only permitted on the reef

Wave Runner

Drive and Speed on board of a 700 Yamaha wave runner across the Caribbean Sea.

Duration: 30 minutes
Please be at the Aquaworld hut (located by the hotel pool) 15 minutes in advance of activity.
Price: $63.80 (Single persons would pay full boat rate)
Gratuity: $5

Inclusive of:
1 Guide per 10 persons
Life jackets and lockers
Bottled water

*Bathing suit, towel, shorts, T-shirts, sandals or wet shoes, sunglasses and water camera recommended.
**Biodegradable suntan lotion is only permitted on the reef**

Sub See

An extraordinary way to admire the marine life and the reef’s ecosystem without getting wet! Be part of this unique adventure on board The Sub See Explorer, a glass bottom boat like a yellow submarine with huge glass panels on the sides, from where you will be able to watch the multi-coloured species of the Scorpion´s coral reef.

Duration: 2 hrs.
Please be at the marina 30 minutes in advance of activity
Capacity: Boat can hold 66 passengers
Price: $46.40 per person
Dock Fee and Reef tax: $10
Gratuity: $5

Inclusive of:
Boat transportation on board of Reef Express
Specialized Guides
Beverages (Beer, Soft Drinks and water)
Bottled Water
TI Staff present

*Bathing suit, towel, shorts, T-shirts, sandals or wet shoes, sunglasses and water camera recommended.
**Biodegradable suntan lotion is only permitted on the reef**

Full Day Activities

To make an enquiry or booking (individual/group), please contact Francisco Mora at Tropical Incentives.

Francisco Mora
Email: guestservices@ticancun.com

A Tropical Incentive representative will also be available during the conference period at the hotel, so should you have any questions about a booked tour you can always ask upon arrival or at any time during your stay.

Our full day tours are offered pre and post conference dates. If you require any additional nights at the Fiesta Americana Condesa due to a full day excursion, please ensure you book these in advance to avoid disappointment. The full days tours are available to both individual and group bookings.

Tulum And Playa Del Carmen Shopping Tour

Our journey begins in the magical ancient Tulum Archaeological Zone, discovered by John L. Stephens in 1842. Perched on top of a cliff facing the Caribbean Sea, it is the only entire walled in-group of Mayan Ruins ever discovered. Under the advice of an official English speaking tour guide, the group will go around the structures getting the history and spirit of the Mayans. Afterwards we head Playa del Carmen, an authentic Mexican town, popular because of its beautiful beaches with turquoise water colour and the famous 5th Avenue where the participants will browse around the shops aside to explore. All kind of typical items, handcrafts, pottery, typical rugs most of them hand made by top artisans, fine boutiques selling everything imaginable. A unique experience! A group lunch can be arranged in one of the restaurants or it can be at leisure.

Ek Balam and Cenote

Visit the archaeological site of Ek-Balam. Ek Balam means Bright Star Jaguar in Maya language. This ancient Maya city had its glory before Chichen Itza. This archaeological site is one of the latest attractions because of its most recent restoration. Discover the mysterious Maya Cenote, enjoy its beautiful natural formations and great natural pool of 80m diameter. During the tour you will see different Maya communities. Take home your memories with the beautiful photographs taken by native photographers during the activities.

Sea Passion Catamaran

Isla Mujeres (Island of Women) is one of the Mexican Caribbean’s favourite destinations. Sail the beautiful turquoise bay from Cancun to Isla Mujeres aboard the Sea Passion I or Sea Passion III, a one-of-a-kind 75 & 60 foot maxi-catamarans, designed for passenger comfort. Enjoy a sail and snorkelling in the National Marine Park. Relax. In the full day activity the participants will have the opportunity to disembark in the Island. You can enjoy exquisite dining at the Beach Club “ElPescador” and the overwhelming views of the turquoise ocean decorated by coconut palm trees and hammocks.

Selvatica Extreme Canopy Tour

Located between Cancun and Playa del Carmen, only 35 minutes form Cancun’s International Airport. Over 250 acres of Tropical Jungle, in Selvatica you will be able to experience a unique adventure in the longest zip-line circuit  in North America, recognized by Travel & Leisure magazine as one of the 35 great adventures in the World, divided in 12 zip lines varying in lengths and heights from 270 ft. to over 2,000 ft, it will make you fly over the jungle. Take a ride on a military vehicle through the jungle to get to the millenary natural cenote. With crystal and pristine waters you will be able to swim choosing between a water zip line or the diving platform. Live this unique and exciting adventure and feel the emotion and adrenaline running through your body.

Coba

Deep in the heart of the Quintana Roo jungle and only 24 miles from southwest of Tulum, approximately 2 1/2 south of Cancun is COBA, an archaeological site that dates from the Classis period. Unlike other Mayan sites in Quintana Roo, Coba was still occupied after the Spanish Conquest. 
This incredible Site once occupied an area of almost 100 square kilometers (60 st. miles). The pyramid of Nohoch Mul-43 meters (130  ft.) high-is the tallest pre-Hispanic structure in the Yucatan peninsula. The main pyramids are the Coba Group, near the entrance, Las Pinturas (The Paintings), named because of the colour still visible on the arches; the Macanxoc, located next to Macanxoc Lake; and Chumuc Mul, the main stucco pyramid which still contains its original colour. 
After a very cultural tour, be prepared to enjoy a delicious lunch in one of the magic restaurants of the area.

For further details on the above and other tours available please contact Tropical Incentives where Francisco Mora or an alternative representative will be happy to assist you.

Contact: Francisco Mora
Email: guestservices@ticancun.com

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Group Activities

At present there are no group activities available.

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Childcare

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Oral Presenters

Once registered for the conference you will be able to submit your abstract online and monitor the status through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Oral Presentations

We have a number of oral opportunities available at this meeting. To be considered for an oral presentation, please submit your abstract within the 'Talk Deadline'. Please check the conference programme carefully to note your presentation time (inclusive of Q&A) should you be accepted for an oral presentation.

We recommend you check our website regularly as the conference approaches as regular programme updates will be released under the ‘Programme’ tab on the conference page.

If you have prepared some slides to compliment your presentation please ensure you bring these with you on a USB or portable file saving device.

Those presenting on the first day, please email your slides to us so we can have everything prepared and ready for the first session. Please email your slides to:powerpoint@fusion-conferences.com

Flash Presentations

The Flash Session lasts up to 45minutes. This time is evenly divided between all the Flash Presentations that are accepted so your allocated time can range from 3-5 minutes, depending on popularity. The flash session is an extension of the Poster Session and is designed to offer a select few the opportunity to present orally their poster in a more formal, group setting. To be considered for a flash presentation, please submit your abstract within the 'Talk Deadline'. Abstracts submitted after the 'Talk Deadline' may not be accepted.

Please note, the exact length of your presentation will be noted on the conference programme under the ‘Flash Session’.

At the Conference

On the day of your presentation please make yourself known to the AV team who will be available in the conference room. They will ensure they have everything they need, including your presentation slides or aides. If you have any animations or videos we do advise to run through the presentation with the AV tech just to make sure everything is compatible. We also advise that all speakers make themselves known to the AV tech in the conference room immediately before your session beings. The AV tech will apply your microphone and provide a laser pointer should you have a complimenting presentation. Please note, speakers are not permitted to use their individual laptops, our AV tech will have a master laptop for you to run your presentation from. If you have any questions, please don’t hesitate to approach our AV tech or a member of the Fusion team. We are here to help!

We would like to ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time slot decreases.

Download Abstract Template

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Posters

2015 DNA Poster Prize

The conference chairs will be awarding 3 poster prizes for the best poster display and presentation. To be in with a chance of winning, submit your poster by 21 November 2014. The winners will be selected shortly after the Poster Session and each winner will receive a $250 cheque!

Once registered for the conference you will be able to submit your abstract online and monitor the status through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Poster Presentations

Poster submissions will be accepted up until 21 November 2014. Please check the conference programme carefully to note the poster session date and time. Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation only. Posters exceeding this size may not fit on the poster boards provided and therefore you will be unable to present your poster, so please kindly keep to these measurements.

At the Conference

During registration at the conference, if you are presenting a poster please request a poster number from the registration desk. Please do not put up your poster without notifying a member of the Fusion team. Certain adhesive agents are not permitted at some venues therefore; Fusion will be the sole provider of all poster fixings.

You can put up your poster from registration with the help of the Fusion team. Your poster can remain on display for the entire duration of the conference and we ask that you take down your poster on the final day of the meeting. The poster session is usually scheduled on Day 3, but please check the official programme for exact timings. Refreshments will be provided and the poster prizes will be awarded during the conference Gala Night. 

Download Abstract Template

Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy


12 Feb 2015 - 15 Feb 2015

Cancun, Mexico

Chairs

Helen Piwnica-Worms
The University of Texas MD Anderson Cancer Center
Junjie Chen
The University of Texas MD Anderson Cancer Center

Conference History

12 Feb 2015, 15 Feb 2015

Exploring DNA Repair Pathways as Targets for Cancer Therapy

Target DNA repair for Cancer Therapy

Fiesta Americana Condesa, Cancun, Mexico

The first in the series of the Exploring DNA Repair Pathways as Targets for Cancer Therapy Fusion conferences.&nbsp; Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows the ac...

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27 Feb 2017, 02 Mar 2017

2nd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

Target DNA repair for Cancer Therapy

Fiesta Americana Condesa, Cancun, Mexico

Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows theaccumulation of multiple genetic alternations, which are essential for the initiation of tumorigenesis. This has been clearly illu...

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23 Feb 2019, 26 Feb 2019

3rd Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

Melia Nassau Beach All Inclusive, Nassau, Bahamas

Defect in DNA damage repair and checkpoint control is the underlying mechanism for tumorigenesis, since it allows the accumulation of multiple genetic alternations, which are essential for the initiation of tumorigenesis. This has been clearly ill...

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20 Feb 2021, 23 Feb 2021

4th Exploring DNA Repair Pathways as Targets for Cancer Therapy Conference

#FusionDNA21

Fiesta Americana Puerto Vallarta All Inclusive, Puerto Vallarta, Mexico

Defects in DNA damage repair and checkpoint control are underlying mechanisms driving tumorigenesis, since they allow for the accumulation of genetic alternations. In addition, defects associated with these pathways are the underlying cause of sev...

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Supported By

Gold
Bronze
If you're interested in sponsoring this conference please contact us.