Synopsis
A plethora of genetic, dietary and pharmacological interventions can extend healthy lifespan in laboratory animals, and can delay or ameliorate diverse aging-related diseases. Mechanisms of aging are conserved in evolution, and discoveries made in animals are informing our understanding of human aging. This raises the intriguing possibility of performing preventative medicine against chronic and age-related diseases, by targeting their main risk factor, namely aging. Important current challenges in the field are (1) to understand the downstream pathways by which longevity interventions can combat age-related loss of function and pathology, (2) to evaluate the impact of regenerative interventions and cellular reprogramming on age-related diseases, and (3) to translate the findings into the extension of human health span.
This fourth meeting will continue to explore these topics, with particular emphasis on what we can learn from variation in the rate of ageing in the natural world, mitochondria, cellular senescence, biomarkers and epidemiology, immune aging and reprogramming and rejuvenation strategies.
Key Sessions
- Mitochondrial quality control and aging
- Ultra long lives and immortality
- Autophagy and proteostasis
- Regenerative interventions and cellular reprogramming
- Human ageing: biomarkers and cell senescence
- Microbiome and aging
Student Offer
Take advantage of this fantastic opportunity for students! Fully paying academics can bring a student for only €882. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 11, 12, 13 October 2023 (on a shared basis for students) and a food and beverage package for the conference period. Once registered, please contact Emily Meen to obtain a special registration link for your student.
Confirmed Plenary Speakers
Yves Barral (ETH Zurich)
ROLE OF THE NUCLEAR ENVELOPE IN CELLULAR AGEING
Ivan Dikic (Goethe University)
AGEING AND QUALITY CONTROL NETWORKS
Joan Mannick (Tornado Therapeutics)
USING mTOR INHIBITORS TO TARGET AGING BIOLOGY IN HUMANS
Wolf Reik (Altos Labs)
EPIGENETIC GENE REGULATION IN DEVELOPMENT AND AGEING
Masayo Takahashi (Vision Care, Inc)
FUTURE OF RETINAL REGENERATIVE MEDICINE
Confirmed Invited Speakers
Andrea Ablasser (EPFL)
SENSING DNA AS A DANGER SIGNAL THROUGH THE cGAS-STING PATHWAY
Andreas Beyer (CECAD Cologne)
AGING-ASSOCIATED REWIRING OF TRANSCRIPTIONAL REGULATION
Seth Blackshaw (Johns Hopkins University)
Helena Cochemé (MRC London Institute of Medical Sciences)
REDOX SIGNALLING IN AGEING
Joris Deelen (Max Planck Institute for Biology of Aging)
UNRAVELLING THE SECRETS OF HEALTHY AGEING BY STUDYING THE GENETIC MAKE-UP OF LONG-LIVED INDIVIDUALS
Martin Denzel (Altos Labs)
TUNING mRNA TRANSLATION TO ENHANCE ROBUSTNESS AND INCREASE SURVIVAL
Judith Frydman (Stanford University)
Vera Gorbunova (University of Rochester)
MECHANISMS OF LONGEVITY
Shukry James Habib (Université de Lausanne)
REJUVENATING AND REPAIRING AGED BONES
Malene Hansen (Buck Institute for Research on Aging)
REGULATION OF AUTOPHAGY IN AGING AND DISEASE
Cole Haynes (University of Massachusetts)
ACTIVITIES THAT CONTRIBUTE MITOCHONDRIAL DYSFUNCTION IN AGING TISSUES
Leanne Jones (University of California, San Francisco)
Brian Kennedy (National University of Singapore)
Viktoria Kheifets (Alkaheist)
Morgan Levine (Altos Labs)
Laura Niedernhofer (University of Minnesota)
Pradeep Reddy (Altos Labs)
Aleksandra Trifunovic (University of Cologne)
MOLECULAR MECHANISMS REGULATING MITOCHONDRIAL STRESS RESPONSES
Anu Suomalainen Wartiovaara (University of Helsinki)
Supported By
Bronze
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