Registration deadlines

Early Bird - 29 Apr 2023

Talk Submission - 05 May 2023

Poster Submission - 18 Aug 2023

Registration Deadline - 18 Aug 2023

Register

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Synopsis

We understand that registering for a conference is not essential right now. Many researchers will be unable to register for a future conference of interest if their organisation is temporarily closed or preventing travel. Therefore, you can simply register your interest here without committing to attending, and our team will keep you updated regarding deadline reminders and grant opportunities. We hope this service is helpful during this difficult time.

This conference is a continuation of the DNA Replication as a Source of DNA Damage series.

The maintenance of genome integrity is critical for the suppression of several pathological disorders in humans, including cancer, infertility and neurodegeneration. Moreover, the accumulation of unrepaired errors in DNA is commonly cited as a likely cause of tissue and organismal ageing. Destabilization of the genome can occur as a result of several cell intrinsic or extrinsic factors, including errors arising during DNA replication or chromosome segregation, as well as exposure of cells to agents that induce DNA damage. In this conference, we aim to bring together scientists studying DNA replication, DNA repair and chromosome segregation with those interested in how chromosomal instability can influence human pathology. Moreover, we aim to show how high throughput and high content screening methods can be used as a discovery tool both for basic science applications and to identify potential therapeutic modalities.

Key Sessions

  • Pathways for repair of DNA damage and disrupted DNA replication forks
  • Screening tools for analysis of genome maintenance pathways and for development of new therapeutics
  • Chromosome fragility caused by difficult-to-replicate loci – sources and roles of DNA repair proteins
  • Chromosome instability as a driver of tumorigenesis, neurodegeneration and ageing
  • Exploitation of defects in chromosome maintenance in cancer treatment

Student Offer

Take advantage of this fantastic opportunity for students! Fully paying academics can bring a student for only €882. Unfortunately, Postdocs are not eligible for this offer. Both registration packages include; accommodation for the 14, 15, 16 October 2023 (on a shared basis for students) and a food and beverage package for the conference period. Once registered, please contact Jack Peters to obtain a special registration link for your student.

Confirmed Invited Speakers

Monica Bettancour-Dias (Instituto Gulbenkian de Ciência)
María Blasco (Spanish National Cancer Research Center)
Keith Caldecott (University of Sussex)
DNA STRAND BREAK REPAIR AND HUMAN DISEASE
Vincenzo Costanzo (IFOM)
CAUSES AND CONSEQUENCES OF DNA REPLICATION STRESS IN VERTEBRATE ORGANISMS
Daniel Durocher (Lunenfeld-Tanenbaum Research Institute)
PROBING DNA REPAIR WITH SYNTHETIC LETHALITY
Daniel Gerlich (Institute of Molecular Biotechnology)
CONFORMATION OF REPLICATED CHROMOSOMES
Thanos Halazonetis (University of Geneva)
MAPPING DNA REPLICATION ORIGINS IN NORMAL AND CANCER CELLS
Steve Jackson (The Gurdon Institute)
CELLULAR RESPONSES TO DNA DOUBLE-STRAND BREAKS:  MECHANISTIC INSIGHTS AND THERAPEUTIC APPLICATIONS
Andrew Jackson (University of Edinburgh)
RIBONUCLEOTIDE EXCISION REPAIR - GENOME INSTABILITY, MUTAGENESIS, AND INFLAMMATION
Joanna Loizou (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences)
THE DNA DAMAGE RESPONSE IN HEALTH AND DISEASE
Núria López-Bigas (IRB Barcelona)
COMPUTATIONAL ANALYSIS OF THOUSANDS OF CANCER GENOMES TO UNDERSTAND MUTATIONAL PROCESSES
Ana Losada (Spanish National Cancer Research Center)
CONTRIBUTION OF COHESIN MUTATIONS TO AGGRESSIVE EWING SARCOMA
Niels Mailand (Novo Nordisk Foundation Center for Protein Research)
DEFINING THE ESSENTIAL ROLES OF SUMOylation IN CHROMOSOME STABILITY
Marcos Malumbres (Spanish National Cancer Research Center)
René Medema (Netherlands Cancer Institute)
Serena Nik-Zainal (MRC Cancer Unit)
Andre Nussenzweig (National Institutes of Health)
Christopher E. Pearson (The Hospital for Sick Children)
Zuzana Storchova (TU Kaiserslautern)
Steve West (Francis Crick Institute)
SPECIFIC KILLING OF BRCA1 OR BRCA2 DEFICIENT CANCER CELLS BY TARGETING NUCLEOTIDE SALVAGE PATHWAYS

Target Audience

This meeting will appeal to Molecular/Cell Biologists/Geneticists & Biochemists interested in genome stability. Researchers interested in the molecular basis of cancer, neurodegenerative diseases and ageing and those with an interest in high throughput genetic and pharmacological screening methods will also find the conference highly relevant along with those wishing to exploit genome maintenance abnormalities in tumour cells for therapeutic benefit.

Educational Need

Chromosome instability is involved in several human diseases and is a feature of natural ageing. This conference will bridge fundamental studies on the mechanisms by which cells maintain genome stability with applications of these studies aimed at the development of new therapies. Hence, the conference will bridge basic biology and clinical applications in this rapidly advancing field. Attendees should be able to obtain a full picture of the current status of the field, as well as to interact with prominent research leaders driving the clinical application of the latest research.

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Speakers

Speakers to be confirmed.

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Programme

Although the programme has not yet been released, we are able to confirm that the conference should begin no earlier than 14:00 with opening comments on 14th October 2023. The conference will conclude no later than 12:30 on 17th October 2023.


3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Prices

Early Bird Full Price Additional Adult Additional Child Extra Night Adult Extra Night Child
Academic €1456 €1551 €595 €174 €170 €12
Industry €1456 €1551 €595 €174 €170 €12
Student €1182 €1277 €595 €174 €170 €12

All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.

What's Included in our Registration Fees?

Our registration fees are inclusive of the following during the conference period only:

- Conference registration 
- 3 nights’ fixed accommodation (14, 15, 16 October 2023) on a single basis for academics and industry, on a shared basis for students 
- Buffet breakfast in Origano restaurant
- Buffet lunch in the in Origano restaurant with two soft drinks and water
- Buffet dinner in the in Origano restaurant with a glass of wine, or two beers, or two soft drinks and water
- BBQ Gala Dinner with free flow wine, beer, soft drinks and water
- Complimentary WIFI in both conference rooms and your guest room

What's Included in our Accompanying Adult Fees?

Our accompanying adult fees are inclusive of the following during the conference period only:

- 3 nights’ fixed accommodation (14, 15, 16 October 2023) on a shared basis with a conference participant
- Buffet breakfast in Origano restaurant
- Buffet lunch in the in Origano restaurant with two soft drinks and water
- Buffet dinner in the in Origano restaurant with a glass of wine, or two beers, or two soft drinks and water
- BBQ Gala Dinner with free flow wine, beer, soft drinks and water
- Complimentary WIFI in guest room

Important Note: Accompanying persons are not permitted access to the conference. Meals are only available during the times listed in the conference programme and accompanying guests must dine with the group.

What's Included in our Accompanying Child Fees?

Our accompanying child fees are inclusive of the following during the conference period only:

- 3 nights’ fixed accommodation (14, 15, 16 October 2023) on a shared basis with the parent/s
- Buffet breakfast in Origano restaurant
- Buffet lunch in the in Origano restaurant with two soft drinks and water
- Buffet dinner in the in Origano restaurant with two soft drinks and water
- BBQ Gala Dinner with free flow soft drinks and water
- Complimentary WIFI in guest room

Important Note: Meals are only available during the times listed in the conference programme and accompanying children must dine with the group. Accompanying child fees are applicable for children aged 2-12 years. Children under 2 years stay free of charge and children aged 13-17 years are classified as an adult. Please see below for an overview of suitable family room types.

2 adults 1 child (younger than 2 yrs) – Standard hotel room (with cot) or 1 bedroom residence (with sofa bed)
2 adults 1 child (2-12 yrs) – 1 bedroom residence (with sofa bed)
2 adults 2 children (0-12 yrs) - 1 bedroom residence (with sofa bed)

Please notify a member of the Fusion team when adding accompanying children to your booking so we can assist with your reservation and check the correct room type is available for your stay.

Please kindly ensure your child / children are supervised at all times during conference and related events. Childcare services are available at the hotel, please contact Jack Peters for further information.

What's Included in our Extra Night Fees?

- 1 night’s accommodation for 1 person
- Buffet breakfast in Origano restaurant
- Complimentary WIFI in your guest room

Important Note: Extra night child fees are applicable for children aged 2-12 years. Children under 2 years stay free of charge and children aged 13-17 years are classified as an adult. Please see below for an overview of suitable family room types.

2 adults 1 child (younger than 2 yrs) – Standard hotel room (with cot) or 1 bedroom residence (with sofa bed)
2 adults 1 child (2-12 yrs) – 1 bedroom residence (with sofa bed)
2 adults 2 children (0-12 yrs) - 1 bedroom residence (with sofa bed)

Please notify a member of the Fusion team when adding accompanying children to your booking so we can assist with your reservation and check the correct room type is available for your stay.
 

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

LinkedIn forum

The DNA Research Network is an excellent platform to connect with fellow attendees and likeminded researchers prior to the conference. 

The Linkedin Group is designed to bring together the global community of researchers and scientists interested in the study of DNA. Relevant specialties are wide-ranging, reflecting the importance of DNA Research in many aspects of health and disease, including; DNA Repair, DNA Replication, DNA Damage, Cancer, Chromosomal Instability, RNA and Nucleic Acids. The group is open to all and is intended as a networking forum for past, present and future participants of Fusion Conferences as well as those interested in the related topics.

Join our group

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Venue

Sun Gardens Dubrovnik

Venue Rating
Currency
Euro (EUR)
Address
Dubrovački Vrtovi Sunca d.o.o. Na Moru 1, 20235 Orašac, Dubrovnik
Nearest Airport
Dubrovnik International Airport

We are excited to be adding a beautiful Adriatic destination to our portfolio for autumn 2023 – the Sun Gardens Dubrovnik in Croatia. The resort is nestled into the hillside with uninterrupted, stunning views of the ocean. 

This beautiful hotel is located only 11 km from Dubrovnik city centre, in the small village of Orašac, nestled amongst the citrus groves, palm trees and gorgeous blue sea that characterize the city, The Old City, a UNESCO World Heritage Site with magnificent defensive walls surrounding it, is just one of the wonderful places to visit. With stunning architecture, scenic walks, wine tasting, boat trips and beautiful beaches, there is plenty to inspire when exploring beyond the hotel. We truly believe Croatia will become a firm favourite with our delegates.

The hotel boasts several wonderful dining options with a mix of Dalmatian, Mediterranean, international and fusion culinary experiences. Or you may want to take in the stunning views of the sea and the nearby islands as you unwind, relax and catch up on the day’s events in one of the hotels bars. Pools, a promenade, spa, sports centre and beaches are just a few of the other facilities you will find available during your stay. 

This is not an all-inclusive property, but we have arranged a full food and beverage package for delegates during the conference period which is included within the registration fee. Breakfast will be at leisure each morning, but participants will dine together for conference lunches and dinners. For anyone staying any extra nights, the rate will be bed and breakfast only so delegates can choose whether to dine at the hotel or explore and eat elsewhere. 

Hotel facilities include;
•    Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
•    3 Pools
•    Spa
•    Gym & Sports Center
•    8 Restaurants
•    9 Bars
•    Kids Club
•    Beach
 

Location

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Transportation

The hotel is approximately 40 minutes from Dubrovnik Airport, the second largest international airport in Croatia. Europeans will find this fairly easy to get to and from New York also offer a direct flight option for anyone travelling from the US. The most common flights into Dubrovnik are from Zagreb and Frankfurt so these are popular choices for interconnecting flights.

Airport transfer details and recommended suppliers will be available shorlty.

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Local Activities

Local activity details will be announced here soon. 

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Group Activities

To be announced

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Childcare

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Oral Presenters

We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.

Your Presentation

On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.

Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.

We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.

Please make sure your presentation adheres to the following guidelines.

Aspect Ratio: On Screen Show (16:9)
File Type: Please save your presentation in PPT, PPTS or Keynote format.

Download Abstract Template

3rd Chromosomal Instability as a Driver of Human Disease Conference

14 Oct 2023 - 17 Oct 2023

Dubrovnik, Croatia

Chairs

Posters

We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you. 

Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.

Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.

Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.

Download Abstract Template