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Registration deadlines

Early Bird - 31 Jan 2022

Talk Submission - 31 Jan 2022

Poster Submission - 04 Mar 2022

Registration Deadline - 04 Mar 2022

Register

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Synopsis

Although conferences can boost productivity and enable research sucesses, we understand that registering for a conference may be challenging right now. Many researchers will be unable to register for a future conference of interest if their organisation is temporarily preventing travel. Therefore, you can simply register your interest here without committing to attending, and our team will keep you updated regarding deadline reminders and grant opportunities. We hope this service is helpful and supports you research goals during this difficult time.

Future master keys to cancer biology and advanced therapies are being forged from mechanistic understanding of the intertwined roles of DNA repair with DNA replication stress, transcription and immune responses. The remarkable stability of the human genome is lost in cancer cells due to the failure of efficient and accurate DNA repair in the context of oncogene-induced replication stress and elevated transcription. In fact, DNA repair complexes are frequently found at the convergence of multiple processes critical for cancer development, making their elucidation of fundamental biological and medical importance. Moreover, the synthetic lethality and essentiality resulting from repair-replication stresses suggest strategies and tactics for advanced therapeutics that target Achilles heels for cancer. Furthermore, epigenetics, non-coding RNA, phase condensates and microbiome are emerging as increasingly important players/processes in cancer biology and cancer progression, and as potential therapeutic targets.

The 5th DNA Repair/Replication Structures & Cancer conference in May 2022 will focus on structural and mechanistic insights into dynamic complexes acting in DNA repair and its interface with replication, transcription and other cancer-relevant transactions. This fundamental information will be pivotal for the accurate interpretation of cancer clinical data, design of clinical trials, prognosis, etiology and improving the currently 1/20 low success rate for oncology drug clinical trials. Informative talks and poster sessions along with vibrant discussions will foster productive interactions, collaborations, and insights.

To advance understanding, all presenters are asked to focus on unpublished work, cutting-edge approaches and mechanistic insights that aid prediction of biological outcomes and plans to best apply basic research advances for cancer research and treatment. To include late-breaking advances and innovating new investigators, multiple talks will be selected from submitted abstracts. As meeting attendance is limited to ensure effective discussions and interactions, delegates are strongly encouraged to submit applications and abstracts early to avoid disappointment.

What makes this meeting unique? Professor Ben Van Houten from the University of Pittsburgh says:

‘I can honestly say your meeting, by combining hard core structure-function studies with beautiful biology, hits an important area that many meetings miss; being part of that science is just terrific.’

Key Sessions

Sessions will include emerging results and breakthrough methodologies on core topics including:

  • Repair and replication complexes, structures and mechanisms
  • Epigenetics and non-coding RNA 
  • Mutational signatures, DNA repair, and cancer
  • Intertwined repair interactions with transcription and replication stress
  • Posttranslational modifications, phase condensates, and repair  
  • Links to microbiome, inflammation and immune responses 
  • Targeting synthetic lethality and essentiality for damage responses

Therapeutics Session

This year we are super excited to include a session dedicated to DDR-based cancer therapeutics, highlighting a number of new DDR agents that have recently entered the clinic, alongside more established DDR inhibitors, the use of DDR-based technology that has potential translational science utility both in the lab and the clinic, as well as an overview of the opportunities and challenges associated with developing new DDR-based medicines for cancer patients.

We are joined by the following incredible speakers:

Mark O'Connor, Chief Scientist Oncology R&D, AstraZeneca
Discussing next generation PARP inhibitors.
Frank Zenke, Head of DNA Damage Response Research, Merck KGaA
Discussing the preclinical and clinical exploration of ATR inhibitors.
Helen Robinson, VP of Biology, Artios
Discussing the discovery and development of polymerase theta inhibitors.
Magda Kordon, CEO & Co-Founder, intoDNA
Discussing how DNA STRIDE technology is being used to advance DDR inhibitor drug discovery and development.
Timothy Yap, Medical Director, Institute for Applied Cancer Science, MD Anderson Cancer Center
Discussing what it means to test DDR inhibitors in the clinic.

Student Offer

Take advantage of this fantastic opportunity for students and postdocs! Fully paying academics can bring one student or postdoc for only $900. Both registration packages include accommodation for the 27th, 28th, 29th and 30th April 2022 (on a shared basis for students/postdocs) and a food and beverage package for the conference period. Once registered, please contact Laura Trundle to obtain a special registration link for your student or postdoc.

Confirmed Plenary Speakers

Lorena Beese (Duke University)
Steve Kowalczykowski (University of California, Davis)
CONTROL AND MECHANISM OF DNA RESECTION
Amanda Chaplin & Tom Blundell (University of Cambridge)
Cryo-EM OF NHEJ MULTICOMPONENT SUPERCOMPLEXES

Confirmed Invited Speakers

Ivan Ahel (University of Oxford)
ADP-RIBOSYLATION SIGNALLING IN REGULATION OF DNA DAMAGE RESPONSE
Aura Carreira (Institut Curie)
INSIGHTS ON BRCA2 FUNCTIONAL DOMAINS FROM BREAST CANCER VARIANTS
Walter Chazin (Vanderbilt University)
WHICH WILL IT BE: REPLICATION, REMODELING OR REPAIR AT THE REPLICATION FORK?
Junjie Chen (MD Anderson Cancer Center)
TARGETING DNA DAMAGE RESPONSIVE PATHWAYS FOR CANCER THERAPY
Patrick Cramer (Max Planck Institute for Biophysical Chemistry)
STRUCTURAL STUDIES OF EUKARYOTIC TRANSCRIPTION-COUPLED DNA REPAIR
Sylvie Doublie (University of Vermont)
Angela Eggleston (Nature)
THE IMPACT OF cryoEM ON OUR UNDERSTANDING OF DNA REPAIR
Dorothy Erie (University of North Carolina at Chapel Hill)
SINGLE-MOLECULE STUDIES OF DNA REPAIR ENZYMES
Yuan He (Northwestern University)
STRUCTURAL BASIS OF DNA DOUBLE-STRAND BREAK REPAIR BY NHEJ
Karl-Peter Hopfner (Ludwig-Maximilians-University Munich)
MECHANISM OF DNA DOUBLE-STRAND BREAK SENSING AND PROCESSING BY THE Mre11-Rad50 COMPLEX
Caroline Kisker (University of Würzburg)
HOW TO LIMIT THE SPEED OF A MOTOR - THE INTRICATE REGULATION OF THE XPB ATPase AND TRANSLOCASE IN TFIIH
Magda Kordon (intoDNA)
Carolyn Larabell (Lawrence Berkeley National Laboratory)
LABEL-FREE IMAGING OF NUCLEAR ORGANIZATION WITH SOFT X-RAY TOMOGRAPHY
Susan Lees-Miller (University of Calgary)
STRUCTURAL INSIGHTS INTO NON-HOMOLOGOUS END-JOINING
Gaëlle Legube (University of Toulouse)
CHROMATIN AND CHROMOSOME DYNAMICS IN DSB REPAIR
Jo Morris (University of Birmingham)
Mark O'Connor (AstraZeneca)
DEVELOPING A NEXT-GENERATION PARP1-SELECTIVE INHIBITOR TO TREAT CANCER
John Pascal (University of Montreal)
POLY(ADP-ribose) POLYMERASE ENZYMES AS SENSORS OF DNA DAMAGE AND TARGETS FOR CANCER THERAPY
Helen Robinson (Artios)
Eli Rothenberg (NYU Langone Health)
MECHANISMS OF REPLICATION FORK REMODELING AND REPAIR VIA SINGLE-MOLECULE IMAGING
Katharina Schlacher (MD Anderson Cancer Center)
NUCLEAR AND MITOCHONDRIAL GENOME INSTABILITY IN DISEASE AND INFLAMMATION
Titia Sixma (Netherlands Cancer Institute)
Joann Sweasy (University of Arizona)
BASE EXCISION REPAIR AND HUMAN DISEASE
Nicolas Thoma (Friedrich Miescher Institute)
HOW TO BIND DNA IN THE CONTEXT OF CHROMATIN
Ben Van Houten (UPMC Hillman Cancer Center)
THE ROLE OF UV-DDB IN BASE EXCISION REPAIR: FROM SINGLE MOLECULES TO CELLS
Steve West (Francis Crick Institute)
SENSITISATION OF BRCA-DEFECTIVE CANCERS BY FACTORS THAT DISRUPT REPLICATION FORK STABILITY
Dale Wigley (Imperial College London)
MECHANISM AND REGULATION OF INO80-FAMILY REMODELLERS
Scott Williams (NIH)
MOLECULAR MECHANISMS OF DNA REPAIR FACTORS IMPACTED IN HERITABLE ATAXIA SYNDROMES
Wei Yang (NIH)
Timothy Yap (MD Anderson Cancer Center)
Frank Zenka (Merck KGaA)
Shan Zha (Columbia University Medical Center)
THE FUNCTIONAL IMPACTS OF KU C-terminal DOMAINS IN NON-HOMOLOGOUS END-JOINING AND BEYOND
Xiaolan Zhao (Memorial Sloan Kettering Cancer Center)
INTEGRATIVE ANALYSIS REVEALS UNIQUE STRUCTURAL AND FUNCTIONAL FEATURES OF THE Smc5/6 COMPLEX

Target Audience

Academic and industrial researchers (including established and junior principal investigators, postdoctoral fellows and PhD students) interested in DNA damage responses and cancer including their intersection with replication, transcription, epigenetics, non-coding RNA, posttranslational modifications, cancer biology, and cancer drug discovery. The focus will be the molecular mechanisms of and interfaces controlling damage responses and cancer biology.

Educational Need

This conference will bring together scientists working at the forefront of DNA repair, replication, transcription, epigenetics, non-coding RNA, post-translational modification including PARylation, and cancer biology. Presentations will consider diverse cutting-edge methodologies and integrated approaches to investigate the structures and mechanisms of dynamic protein, chromatin, DNA and RNA complexes. The conference will showcase breakthrough advances and new developments in these areas. It will furthermore provide opportunities for industry and academia to consider and exchange their latest results in this exciting, rapidly advancing arena. The inter-disciplinary nature of the presented work will create strong synergies among participants and outstanding opportunities for exchanging information and developing new collaborations. The cross-disciplinary interactions will be invaluable training for young scientists to work in these and other emerging areas of science.

4th DRRSC Photos

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Speakers

Plenary Speakers

Invited Speakers

Joann Sweasy

Professor, University of Arizona

Patrick Cramer

Director, Max Planck Institute for Biophysical Chemistry

Aura Carreira

Group leader, Institut Curie

Amanda Chaplin

Postdoctoral Researcher, University of Cambridge

Karl-Peter Hopfner

Professor, Gene Center

Xiaolan Zhao

Professor, Memorial Sloan-Kettering Cancer Center

Caroline Kisker

Professor, University of Wuerzburg

Katharina Schlacher

Assistant Professor, MD Anderson Cancer Center

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Programme

Please note the programme is subject to change.
Discussion is valued: 5 minutes is saved for discussion following each talk.

WEDNESDAY 27TH APRIL 2022

15:00 – 16:00

Student & Postdoc Networking Lunch

15:00 – 16:00

Registration & Refreshments

16:00 – 16:15

Opening Comments by John Tainer, Xiaodong Zhang & Tom Blundell

WEDNESDAY PM

DSB repair – NHEJ machines and Cancer Biology
Session Chair: TBA

16:15 – 16:20

Session Introduction

16:20 – 16:40

Susan Lees-Miller
University of Calgary

STRUCTURAL INSIGHTS INTO NON-HOMOLOGOUS END-JOINING

16:45 – 17:05

Yuan He
Northwestern University

STRUCTURAL BASIS OF DNA DOUBLE-STRAND BREAK REPAIR BY NHEJ

17:10 – 17:20

Short Talk *

To be selected from abstracts

17:25 – 17:55

Meet the Poster Presenters I

17:55 – 18:15

Refreshments

18:15 – 18:45

Meet the Poster Presenters II

18:45 – 19:05

Shan Zha
Columbia University Medical Center

THE FUNCTIONAL IMPACTS OF KU C-terminal DOMAINS IN NON-HOMOLOGOUS END-JOINING AND BEYOND

19:10 – 19:40

Amanda Chaplin & Tom Blundell
University of Cambridge

Cryo-EM OF NHEJ MULTICOMPONENT SUPERCOMPLEXES

19:45

Group Dinner

THURSDAY 28TH APRIL 2022

07:00 – 08:30

Breakfast at Leisure

THURSDAY AM

Replication Instability and Cancer
Session Chair: TBA

08:30 – 08:35

Session Introduction

08:35 – 08:55

Steve West
Francis Crick Institute

SENSITISATION OF BRCA-DEFECTIVE CANCERS BY FACTORS THAT DISRUPT REPLICATION FORK STABILITY

09:00 – 09:20

Jo Morris
University of Birmingham

TBC

09:25 – 09:35

Xiaohua Wu *
The Scripps Research Institute

STUDY BREAK-INDUCED REPLICATION IN MAMMALIAN CELLS

09:40 – 09:50

Margherita Botto *
Leiden University Medical Center

A FOUR-POINT MOLECULAR HANDOVER DURING OKAZAKI MATURATION

09:55 – 10:15

Titia Sixma
Netherlands Cancer Institute

TBC

10:20 – 11:00

Refreshments & Poster Viewing

THURSDAY AM II

Replication/Repair Interface
Session Chair: TBA

11:00 – 11:20

Wei Yang
NIH

TBC

11:25 – 11:45

Walter Chazin
Vanderbilt University

WHICH WILL IT BE: REPLICATION, REMODELING OR REPAIR AT THE REPLICATION FORK?

11:50 – 12:00

Patrick Herr *
University of Sheffield

NUDT22 COUNTERACTS REPLICATION STRESS THROUGH A NOVEL PYRIMIDINE SALVAGE PATHWAY

12:05 – 12:25

Eli Rothenberg
NYU Langone Health

MECHANISMS OF REPLICATION FORK REMODELING AND REPAIR VIA SINGLE-MOLECULE IMAGING

12:30 – 12:40

LUMICKS

TBC

12:45 – 16:30

Lunch at Leisure & Free Time

THURSDAY PM

Mismatch and Base Excision Repairs: From Molecules to Cells and Disease
Session Chair: TBA

16:30 – 16:35

Session Introduction

16:35 – 16:55

Ben Van Houten
UPMC Hillman Cancer Center

THE ROLE OF UV-DDB IN BASE EXCISION REPAIR: FROM SINGLE MOLECULES TO CELLS

17:00 – 17:20

Joann Sweasy 
University of Arizona

BASE EXCISION REPAIR AND HUMAN DISEASE

17:25 – 17:45

Sylvie Doublie 
University of Vermont

TBC

17:50 – 18:00

Short Talk *

To be selected from abstracts

18:05 – 18:35

Plenary: Lorena Beese
Duke University

TBC

18:40 – 20:00

Poster Session & Refreshments (even poster numbers only)

20:00

Dinner at Leisure

FRIDAY 29TH APRIL 2022

07:00 – 08:25

Breakfast at Leisure

FRIDAY AM

Targeting DNA Damage Responses for Cancer Therapy
Session Chair: Mark O’Connor

08:25 – 08:30

Session Introduction

08:30 – 08:50

Mark O'Connor 
AstraZeneca

DEVELOPING A NEXT-GENERATION PARP1-SELECTIVE INHIBITOR TO TREAT CANCER

08:55 – 09:15

Frank Zenka
Merck KGaA

TBC

09:20 – 09:40

Helen Robinson
Artios

TBC

09:45 – 10:05

Magda Kordon
intoDNA

TBC

10:10 – 10:30

Timothy Yap
MD Anderson Cancer Center

TBC

10:35 – 11:20

Group Photo, Refreshments & Poster Viewing

FRIDAY AM II

RNA, Transcription and Repair
Session Chair: TBA

11:20 – 11:25

Session Introduction

11:25 – 11:45

Patrick Cramer
Max Planck Institute for Biophysical Chemistry

STRUCTURAL STUDIES OF EUKARYOTIC TRANSCRIPTION-COUPLED DNA REPAIR

11:50 – 12:10

Caroline Kisker 
University of Würzburg

HOW TO LIMIT THE SPEED OF A MOTOR - THE INTRICATE REGULATION OF THE XPB ATPase AND TRANSLOCASE IN TFIIH

12:15 – 12:25

Ivaylo Ivanov *
Georgia State University

MOLECULAR MECHANISM OF RAD26-ASSISTED RESCUE OF STALLED RNA POLYMERASE II IN TRANSCRIPTION-COUPLED REPAIR

12:30 – 12:40

Michal Roman Szymanski *
University of Gdansk and Medical University of Gdansk

RNA PRIMER REMOVAL IN HUMAN MITOCHONDRIA

12:45 – 12:55

Short Talk *

To be selected from abstracts

13:00 – 17:00

Lunch at Leisure & Free Time

FRIDAY PM

DSB Repair – HR and Cancer
Session Chair: TBA

17:00 – 17:05

Session Introduction

17:05 – 17:25

Karl-Peter Hopfner 
Ludwig-Maximilians-University Munich

MECHANISM OF DNA DOUBLE-STRAND BREAK SENSING AND PROCESSING BY THE Mre11-Rad50 COMPLEX

17:30 – 17:40

Short Talk *

To be selected from abstracts

17:45 – 17:55

Jessica Tyler *
Weill Cornell Medicine

DNA-PK PROMOTES DNA END RESECTION AT DNA DOUBLE STRAND BREAKS IN G0 CELLS

18:00 – 18:30

Plenary: Steve Kowalczykowski 
University of California, Davis

CONTROL AND MECHANISM OF DNA RESECTION

18:35 – 20:05

Poster Session & Refreshments (odd poster numbers only)

20:05

Dinner at Leisure

SATURDAY 30TH APRIL 2022

07:00 – 08:30

Breakfast at Leisure

SATURDAY AM

Damage Sensing, Signaling and Therapeutic Implications
Session Chair: TBA

08:30 – 08:35

Session Introduction

08:35 – 08:55

John Pascal
University of Montreal

POLY(ADP-ribose) POLYMERASE ENZYMES AS SENSORS OF DNA DAMAGE AND TARGETS FOR CANCER THERAPY

09:00 – 09:20

Ivan Ahel
University of Oxford

ADP-RIBOSYLATION SIGNALLING IN REGULATION OF DNA DAMAGE RESPONSE

09:25 – 09:35

Petr Cejka
Institute for Research in Biomedicine

MECHANISM OF DNA END SENSING BY THE MRE11 COMPLEX: IMPLICATIONS FOR CRISPR-BASED GENOME EDITING

09:40 – 10:00

Katharina Schlacher
MD Anderson Cancer Center

NUCLEAR AND MITOCHONDRIAL GENOME INSTABILITY IN DISEASE AND INFLAMMATION

10:05 – 10:25

Carolyn Larabell Lawrence Berkeley National Laboratory

LABEL-FREE IMAGING OF NUCLEAR ORGANIZATION WITH SOFT X-RAY TOMOGRAPHY

10:30 – 11:00

Refreshments & Poster Viewing

SATURDAY AM II

Repair Machines and Mechanisms
Session Chair: TBA

11:00 – 11:05

Session Introduction

11:05 – 11:25

Scott Williams
NIH

MOLECULAR MECHANISMS OF DNA REPAIR FACTORS IMPACTED IN HERITABLE ATAXIA SYNDROMES

11:30 – 11:50

Dorothy Erie
University of North Carolina at Chapel Hill

SINGLE-MOLECULE STUDIES OF DNA REPAIR ENZYMES

11:55 – 12:05

Short Talk *

To be selected from abstracts

12:10 – 12:20

Short Talk *

To be selected from abstracts

12:25 – 12:45

Angela Eggleston
Nature

THE IMPACT OF cryoEM ON OUR UNDERSTANDING OF DNA REPAIR

12:50 – 16:30

Lunch at Leisure & Free Time

SATURDAY PM

DNA Repair in the Context of Chromatin
Session Chair: TBA

16:30 – 16:35

Session Introduction

16:35 – 16:55

Dale Wigley
Imperial College London

MECHANISM AND REGULATION OF INO80-FAMILY REMODELLERS

17:00 – 17:20

Nicolas Thoma
Friedrich Miescher Institute

HOW TO BIND DNA IN THE CONTEXT OF CHROMATIN

17:25 – 17:35

Short Talk *

To be selected from abstracts

17:40 – 18:00

Xiaolan Zhao
Memorial Sloan Kettering Cancer Center

INTEGRATIVE ANALYSIS REVEALS UNIQUE STRUCTURAL AND FUNCTIONAL FEATURES OF THE Smc5/6 COMPLEX

18:05 – 18:25

Gaëlle Legube 
University of Toulouse

CHROMATIN AND CHROMOSOME DYNAMICS IN DSB REPAIR

18:30 – 20:00

Refreshments & Poster Viewing

20:00 – 23:00

Gala Dinner & Poster Awards

SUNDAY 01ST MAY 2022

07:00 – 08:35

Breakfast at Leisure

SUNDAY AM

Damage Response and Decoding Cancer Variants
Session Chair: TBA

08:35 – 08:40

Session Introduction

08:40 – 09:00

Xiaodong Zhang
Imperial College London

MOLECULAR STRUCTURES AND REGULATIONS OF ATR/Mec1 IN DNA DAMAGE SIGNALING

09:05 – 09:25

Junjie Chen
MD Anderson Cancer Center

TARGETING DNA DAMAGE RESPONSIVE PATHWAYS FOR CANCER THERAPY

09:30 - 09:50

Aura Carreira
Institut Curie

INSIGHTS ON BRACA2 FUNCTIONAL DOMAINS FROM BREAST CANCER VARIANTS

09:55 – 10:15

John Tainer
MD Anderson Cancer Center

STRUCTURE AND EVOLUTION DECODES CANCER VARIANTS OF UNKNOWN SIGNIFICANCE

10:20 – 10:30

Closing Comments by John Tainer, Xiaodong Zhang & Tom Blundell


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

* Selected from abstracts.


Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Prices

Early Bird Full Price Additional Adult Additional Child Extra Night Adult Extra Night Child
Academic $1660 $1770 $677 $247 $268 $62
Industry $1660 $1770 $677 $247 $268 $62
Student $1236 $1400 $677 $247 $268 $62

All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.

What's Included in our Registration Fees?

Our registration fees are inclusive of the following during the conference period only:

- Conference registration 
- 3 nights’ fixed accommodation (27, 28, 29, 30 April 2022) on a single basis for academics and industry, on a shared basis for students 
- Breakfast, lunch and dinner available at all restaurants according to their operational hours 
- Unlimited alcoholic beverages, cocktails and soft drinks available by the glass at all restaurants and bars according to their operational hours
- Gala Dinner (includes an open bar)
- 24 hour room service
- Guest room mini bar (replenished daily)
- Complimentary WIFI in both conference rooms and your guest room

What's Included in our Accompanying Adult Fees?

Our accompanying adult fees are inclusive of the following during the conference period only:

- 3 nights’ fixed accommodation (27, 28, 29, 30 April 2022) on a shared basis with a conference participant 
- Breakfast, lunch and dinner available at all restaurants according to their operational hours
- Unlimited alcoholic beverages, cocktails and soft drinks available by the glass at all restaurants and bars according to their operational hours
- Gala Dinner (includes an open bar)
- 24 hour room service
- Guest room mini bar (replenished daily)
- Complimentary WIFI in your guest room

Important Note: Accompanying guests are not permitted access to the conference.

What's Included in our Accompanying Child Fees?

Our accompanying child fees are inclusive of the following during the conference period only:

- 3 nights’ fixed accommodation (27, 28, 29, 30 April 2022) on a shared basis with the parent/s
- Breakfast, lunch and dinner available at all restaurants according to their operational hours
- Unlimited soft drinks available by the glass at all restaurants and bars according to their operational hours
- Gala Dinner 
- 24 hour room service
- Complimentary WIFI in your guest room

Important Note: Accompanying child fees are applicable for children aged 5-12 years. Children younger than 5 years stay free of charge with a parent. Children aged 13 years and older are classified as an adult at this venue (Conrad Tulum Riviera Maya). Please kindly ensure your child / children are supervised at all times during conference and related events. Childcare services are available at the hotel, please contact Laura for further information.

What's Included in our Extra Night Fees?

- 1 night’s accommodation for 1 person
- Breakfast, lunch and dinner available at all restaurants according to their operational hours
- Unlimited alcoholic beverages, cocktails and soft drinks available by the glass at all restaurants and bars according to their operational hours
- 24 hour room service
- Guest room mini bar (replenished daily)
- Complimentary WIFI in your guest room

Important Note: Extra night child fees are applicable for children aged 5-12 years. Children younger than 5 years stay free of charge with a parent. Children aged 13 years and older are classified as an adult at this venue (Conrad Tulum Riviera Maya).

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

LinkedIn forum

Bringing together the global community of researchers and scientists interested in the study of DNA. Relevant specialties are wide-ranging, reflecting the importance of DNA Research in many aspects of health and disease, including; DNA Repair, DNA Replication, DNA Damage, Cancer, Chromosomal Instability, RNA and Nucleic Acids.

The group is open to all and is intended as a networking forum for past, present and future participants of Fusion Conferences as well as those interested in the related topics.

Join our group

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Venue

Conrad Tulum Riviera Maya

Venue Rating
Currency
US Dollar (USD)
Address
Conrad Tulum Riviera Maya Carr. Cancún - Tulum 307, Tulkal 77774 Chemuyil Q.R., Mexico
Nearest Airport
Cancun International Airport

The Conrad Tulum Riviera Maya is a tranquil sanctuary off the beaten path and on the spectacular shores of the Mexican Caribbean. The hotel is nestled amongst the mangroves surrounded by sparkling white sandy beaches, breathtaking sunsets and magnificent views. Located just 8 miles from Tulum, this hidden gem is the perfect destination for those who love admiring, exploring or enjoying nature. Conrad Tulum Riviera Maya will captivate your senses with unparalleled natural views, bold flavors, clear blue skies, a warm coastal breeze and the irresistible aromas of this tropical paradise. We have a feeling this is going to be a new favourite amongst our delegates.

Hotel facilities include;

  • Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
  • 5 Pools
  • Beach
  • Spa
  • Fitness Center
  • 11 Restaurants & Bars

Location

Stretching from the fishing village of Puerto Morelos to the biosphere reserve of Sian Ka'an, the Mayan Riviera offers an unforgettable Caribbean coastline experience with beautiful white-sand beaches and brilliant turquoise colored water. This world-renowned paradise is home to mangroves and lagoons, ancient Mayan cities, ecological reserves and adventure parks, and the world's second largest coral reef.

The hotel is located just a few miles from Tulum, a town on the Caribbean coastline of Mexico’s Yucatán Peninsula. It’s known for its spectacluar beaches and well-preserved ruins of an ancient Mayan port city. The area also offers incredible cavern diving opportunties and beautiful cenotes to explore.

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Transportation

Cancun International airport is approximately 1hr 15minutes from the Conrad Tulum Riviera Maya and is easily accessible from almost every country in the world with many major international airlines providing direct or interconnecting flights on a daily basis.

In the interest of safety, we would recommend booking a private transfer service from the airport to the Conrad Tulum Riviera Maya, however, Taxi services are also available if preferred.

Private Transfers

Maritur are a reputable and reliable DMC based in Cancun & Riviera Maya. The Maritur team will be on hand to provide a seamless transfer service to and from Cancun International Airport. Maritur will manage and confirm all transportation bookings. 

Private transfer service vehicles can accommodate a maximum of 7 persons, plus luggage. Upon arrival at the airport, please exit the terminal building and look for a member of the Maritur team holding a ‘Fusion Conferences’ welcome sign. Please note any transportation services need to be pre-booked with Maritur.

Transfer Rates:

One Way: $105.00 (USD) 

Round Trip: $210.00 (USD)

In the event of any delays or cancellations, please ensure you contact Maritur at least 36 hours in advance; if Maritur are not informed within 36 hours full cancellation charges will apply (Not notified of flight cancellation: 100% penalty charge, No-Shows: 100% penalty charge).

To arrange transportation or make an enquiry, please contact Maritur directly, using their online booking facility (see link below). Please note: Maritur does not use an online payment portal, therefore Wire Transfer is the safest payment option.

https://events.maritur.com/fusion-conference/ 

Taxi

Unlike other Airports, Cancun Airport Taxi Services must be pre-arranged. To obtain safe, licensed and bilingual transportation services please ensure you book your ground transportation online with an authorised transportation company prior to your arrival.

Approximate Fare:

One way (Tulum, Riviera Maya): $64.63+ (USD)
 
*
subject to change, please check the Cancun International Airport website for a more accurate estimation for your trip.

Further information on Taxi services can be found on the Cancun International Airport website (see below link) along with some top tips for travellers from local experts and official authorities. 

https://www.cancunairport.com/taxi.html 


** Please note that Fusion Conferences is not responsible for any bookings made with Maritur or any other transfer/taxi service as transportation is not included within the registration package **

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5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Local Activities

If you wish to explore Tulum or organise an individual trip, we recommend the following activities. We ask that any off-site trips are organised during free time or pre/post conference, to ensure you are fully present for the meeting.

- Gran Cenote. Gran Cenote is a large and popular cenote located just outside Tulum. It is made up of a collection of caves, caverns and an open-air cenote connected by meandering wooden boardwalks and surrounded by lush greens. With its crystal clear waters and underground world, Gran Cenote is popular with swimmers, divers and snorkelers. Approx. 20 minute drive from the hotel. More information - http://todocenotes.com/en-tulum/gran-cenote/

- Tulum Mayan Ruins. The Mayan ruins in Tulum, Mexico, are a must-see attraction for anyone visiting the gorgeous Riviera Maya. Built as a seaport fortress with steep cliffs and limestone walls, the ancient city is one of the best-preserved coastal Maya sites in Mexico, much of which still stands after more than 800 years. Approx. 25 minute drive from the hotel. More information -  https://www.islandlifemexico.com/tulum-ruins-visitors-guide/

- Chichen Itza (Day Trip). Chichen Itza was one of the most important city-states in pre-Hispanic America. It’s one of the 7 Wonders of the World and is one of the most visited archaeological sites in Mexico. Chichen Itza is divided into Old Chichen and Chichen Itza where you can find 6 Mayan Ruins in Old Chichen and around 20 Mayan Ruins in New Chichen or Chichen Itza, making it a total of 26 Mayan Ruins to see on the Mayan Site. Approx. 2 hour 19 minutes drive from the hotel. More information - https://www.chichenitza.com/

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If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Group Activities

We are evaluating suitable group activities with an eye to both safety and interest. Health and safety is highly controlled within the hotel and for any activity providers we will be looking for strong health and safety assurances. Further details will be released approximately four weeks prior to the conference, dependent on guidance at the time.

If you wish to explore Tulum or organise an individual trip, please visit the 'Local Activites' tab for suggestions of places to visit.

Supported By

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Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Childcare

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Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Oral Presenters

We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.

Your Presentation

On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.

Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.

We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.

Please make sure your presentation adheres to the following guidelines.

Aspect Ratio: On Screen Show (16:9)
File Type: Please save your presentation in PPT, PPTS or Keynote format.

Download Abstract Template

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Media Partners
If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Posters

We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you.

Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.

Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.

Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.

Download Abstract Template

Supported By

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If you're interested in sponsoring this conference please contact us.

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22


27 Apr 2022 - 01 May 2022

Riviera Maya, Mexico

Chairs

Conference History

12 Feb 2014, 15 Feb 2014

Dynamic Structures in DNA Damage Responses and Cancer

Fiesta Americana Condesa, Cancun, Mexico

Key sessions will include: DNA and RNA complexes Chromatin Remodeling Post-translational modifications - Ub, SUMO kinases The repair interface with Replication Transcription, and Recomb...

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22 Feb 2016, 25 Feb 2016

2nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference

Fiesta Americana Condesa, Cancun, Mexico

This conference will focus on insights into dynamic DNA and RNA complexes involved in the damage response and cancer. It will emphasize informal as well as formal discussions together with informative talks and...

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11 Feb 2018, 15 Feb 2018

3rd DNA Replication/Repair Structures and Cancer Conference

Fiesta Americana Condesa, Cancun, Mexico

The remarkable stability of the human genome is lost in cancer cells due to the failure of efficient and accurate repair in the context of oncogene-induced replication stress and elevated transcription. DNA replication is furthermore emerging as a...

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16 Feb 2020, 20 Feb 2020

4th DNA Repair/Replication Structures and Cancer Conference

#DRRSC20

Melia Nassau Beach All Inclusive, Nassau, Bahamas

The remarkable stability of the human genome is lost in cancer cells due to the failure of efficient and accurate DNA repair in the context of oncogene-induced replication stress and elevated transcription. Intertwined roles of repair with replica...

More Information

27 Apr 2022, 01 May 2022

5th DNA Repair/Replication Structures and Cancer Conference

#DRRSC22

Conrad Tulum Riviera Maya, Riviera Maya, Mexico

Although conferences can boost productivity and enable research sucesses, we understand that registering for a conference may be challenging right now. Many researchers will be unable to register for a future conference of interest if thei...

More Information

Supported By

Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.