Registration deadlines
Early Bird - 15 Nov 2021
Talk Submission - 15 Nov 2021
Poster Submission - 04 Mar 2022
Registration Deadline - 04 Mar 2022
Register27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
Chairs
Although conferences can boost productivity and enable research sucesses, we understand that registering for a conference may be challenging right now. Many researchers will be unable to register for a future conference of interest if their organisation is temporarily closed or preventing travel. Therefore, you can simply register your interest here without committing to attending, and our team will keep you updated regarding deadline reminders and grant opportunities. We hope this service is helpful and supports you research goals during this difficult time.
Future master keys to cancer biology and advanced therapies are being forged from mechanistic understanding of the intertwined roles of DNA repair with DNA replication stress, transcription and immune responses. The remarkable stability of the human genome is lost in cancer cells due to the failure of efficient and accurate DNA repair in the context of oncogene-induced replication stress and elevated transcription. In fact, DNA repair complexes are frequently found at the convergence of multiple processes critical for cancer development, making their elucidation of fundamental biological and medical importance. Moreover, the synthetic lethality and essentiality resulting from repair-replication stresses suggest strategies and tactics for advanced therapeutics that target Achilles heels for cancer. Furthermore, epigenetics, non-coding RNA, phase condensates and microbiome are emerging as increasingly important players/processes in cancer biology and cancer progression, and as potential therapeutic targets.
The 5th DNA Repair/Replication Structures & Cancer conference in May 2022 will focus on structural and mechanistic insights into dynamic complexes acting in DNA repair and its interface with replication, transcription and other cancer-relevant transactions. This fundamental information will be pivotal for the accurate interpretation of cancer clinical data, design of clinical trials, prognosis, etiology and improving the currently 1/20 low success rate for oncology drug clinical trials. Informative talks and poster sessions along with vibrant discussions will foster productive interactions, collaborations, and insights.
To advance understanding, all presenters are asked to focus on unpublished work, cutting-edge approaches and mechanistic insights that aid prediction of biological outcomes and plans to best apply basic research advances for cancer research and treatment. To include late-breaking advances and innovating new investigators, multiple talks will be selected from submitted abstracts. As meeting attendance is limited to ensure effective discussions and interactions, delegates are strongly encouraged to submit applications and abstracts early to avoid disappointment.
What makes this meeting unique? Professor Ben Van Houten from the University of Pittsburgh says:
‘I can honestly say your meeting, by combining hard core structure-function studies with beautiful biology, hits an important area that many meetings miss; being part of that science is just terrific.’
Sessions will include emerging results and breakthrough methodologies on core topics including:
Take advantage of this fantastic opportunity for students and postdocs! Fully paying academics can bring one student or postdoc for only $900. Both registration packages include accommodation for the 27th, 28th, 29th and 30th April 2022 (on a shared basis for students/postdocs) and a food and beverage package for the conference period. Once registered, please contact Laura Trundle to obtain a special registration link for your student or postdoc.
Lorena Beese (Duke University)
Steve Kowalczykowski (University of California, Davis)
CONTROL AND MECHANISM OF DNA RESECTION
Amanda Chaplin & Tom Blundell (University of Cambridge)
Cryo-EM OF NHEJ MULTICOMPONENT SUPERCOMPLEXES
Ivan Ahel (University of Oxford)
ADP-RIBOSYLATION SIGNALLING IN REGULATION OF DNA DAMAGE RESPONSE
Aura Carreira (Institut Curie)
INSIGHTS ON BRCA2 FUNCTIONAL DOMAINS FROM BREAST CANCER VARIANTS
Walter Chazin (Vanderbilt University)
WHICH WILL IT BE: REPLICATION, REMODELING OR REPAIR AT THE REPLICATION FORK?
Patrick Cramer (Max Planck Institute for Biophysical Chemistry)
STRUCTURAL STUDIES OF EUKARYOTIC TRANSCRIPTION-COUPLED DNA REPAIR
Sylvie Doublie (University of Vermont)
Angela Eggleston (Nature)
THE IMPACT OF cryoEM ON OUR UNDERSTANDING OF DNA REPAIR
Dorothy Erie (University of North Carolina at Chapel Hill)
SINGLE-MOLECULE STUDIES OF DNA REPAIR ENZYMES
Yuan He (Northwestern University)
STRUCTURAL BASIS OF DNA DOUBLE-STRAND BREAK REPAIR BY NHEJ
Karl-Peter Hopfner (Ludwig-Maximilians-University Munich)
Caroline Kisker (University of Würzburg)
Carolyn Larabell (Lawrence Berkeley National Laboratory)
Susan Lees-Miller (University of Calgary)
STRUCTURAL INSIGHTS INTO NON-HOMOLOGOUS END-JOINING
Gaëlle Legube (University of Toulouse)
CHROMATIN AND CHROMOSOME DYNAMICS IN DSB REPAIR
Jo Morris (University of Birmingham)
John Pascal (University of Montreal)
POLY(ADP-ribose) POLYMERASE ENZYMES AS SENSORS OF DNA DAMAGE AND TARGETS FOR CANCER THERAPY
Eli Rothenberg (NYU Langone Health)
MECHANISMS OF REPLICATION FORK REMODELING AND REPAIR VIA SINGLE-MOLECULE IMAGING
Titia Sixma (Netherlands Cancer Institute)
Joann Sweasy (University of Arizona)
Nicolas Thoma (Friedrich Miescher Institute)
HOW TO BIND DNA IN THE CONTEXT OF CHROMATIN
Steve West (Francis Crick Institute)
SENSITISATION OF BRCA-DEFECTIVE CANCERS BY FACTORS THAT DISRUPT REPLICATION FORK STABILITY
Dale Wigley (Imperial College London)
MECHANISM AND REGULATION OF INO80-FAMILY REMODELLERS
Scott Williams (NIH)
Wei Yang (NIH)
Shan Zha (Columbia University Medical Center)
Xiaolan Zhao (Memorial Sloan Kettering Cancer Center)
INTEGRATIVE ANALYSIS REVEALS UNIQUE STRUCTURAL AND FUNCTIONAL FEATURES OF THE Smc5/6 COMPLEX
Academic and industrial researchers (including established and junior principal investigators, postdoctoral fellows and PhD students) interested in DNA damage responses and cancer including their intersection with replication, transcription, epigenetics, non-coding RNA, posttranslational modifications, cancer biology, and cancer drug discovery. The focus will be the molecular mechanisms of and interfaces controlling damage responses and cancer biology.
This conference will bring together scientists working at the forefront of DNA repair, replication, transcription, epigenetics, non-coding RNA, post-translational modification including PARylation, and cancer biology. Presentations will consider diverse cutting-edge methodologies and integrated approaches to investigate the structures and mechanisms of dynamic protein, chromatin, DNA and RNA complexes. The conference will showcase breakthrough advances and new developments in these areas. It will furthermore provide opportunities for industry and academia to consider and exchange their latest results in this exciting, rapidly advancing arena. The inter-disciplinary nature of the presented work will create strong synergies among participants and outstanding opportunities for exchanging information and developing new collaborations. The cross-disciplinary interactions will be invaluable training for young scientists to work in these and other emerging areas of science.
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
Chairs
Joann Sweasy
Professor, University of Arizona
Patrick Cramer
Director, Max Planck Institute for Biophysical Chemistry
Aura Carreira
Group leader, Institut Curie
Amanda Chaplin
Postdoctoral Researcher, University of Cambridge
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
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Although the programme has not yet been released, we are able to confirm that the conference should begin no earlier than 14:00 with opening comments on 27th April 2022. The conference will conclude no later than 12:30 on 01st May 2022.
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
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| Early Bird | Full Price | Additional Adult | Additional Child | Extra Night Adult | Extra Night Child | |
|---|---|---|---|---|---|---|
| Academic | $1660 | $1770 | $677 | $247 | $268 | $62 |
| Industry | $1660 | $1770 | $677 | $247 | $268 | $62 |
| Student | $1236 | $1400 | $677 | $247 | $268 | $62 |
All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.
Our registration fees are inclusive of the following during the conference period only:
- Conference registration
- 3 nights’ fixed accommodation (27, 28, 29, 30 April 2022) on a single basis for academics and industry, on a shared basis for students
- Breakfast, lunch and dinner available at all restaurants according to their operational hours
- Unlimited alcoholic beverages, cocktails and soft drinks available by the glass at all restaurants and bars according to their operational hours
- Gala Dinner (includes an open bar)
- 24 hour room service
- Guest room mini bar (replenished daily)
- Complimentary WIFI in both conference rooms and your guest room
Our accompanying adult fees are inclusive of the following during the conference period only:
- 3 nights’ fixed accommodation (27, 28, 29, 30 April 2022) on a shared basis with a conference participant
- Breakfast, lunch and dinner available at all restaurants according to their operational hours
- Unlimited alcoholic beverages, cocktails and soft drinks available by the glass at all restaurants and bars according to their operational hours
- Gala Dinner (includes an open bar)
- 24 hour room service
- Guest room mini bar (replenished daily)
- Complimentary WIFI in your guest room
Important Note: Accompanying guests are not permitted access to the conference.
Our accompanying child fees are inclusive of the following during the conference period only:
- 3 nights’ fixed accommodation (27, 28, 29, 30 April 2022) on a shared basis with the parent/s
- Breakfast, lunch and dinner available at all restaurants according to their operational hours
- Unlimited soft drinks available by the glass at all restaurants and bars according to their operational hours
- Gala Dinner
- 24 hour room service
- Complimentary WIFI in your guest room
Important Note: Accompanying child fees are applicable for children aged 5-12 years. Children younger than 5 years stay free of charge with a parent. Children aged 13 years and older are classified as an adult at this venue (Fiesta Americana Riviera Maya Tulkal). Please kindly ensure your child / children are supervised at all times during conference and related events. Childcare services are available at the hotel, please contact Laura for further information.
- 1 night’s accommodation for 1 person
- Breakfast, lunch and dinner available at all restaurants according to their operational hours
- Unlimited alcoholic beverages, cocktails and soft drinks available by the glass at all restaurants and bars according to their operational hours
- 24 hour room service
- Guest room mini bar (replenished daily)
- Complimentary WIFI in your guest room
Important Note: Extra night child fees are applicable for children aged 5-12 years. Children younger than 5 years stay free of charge with a parent. Children aged 13 years and older are classified as an adult at this venue (Fiesta Americana Riviera Maya Tulkal).
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
Chairs
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
Chairs
Bringing together the global community of researchers and scientists interested in the study of DNA. Relevant specialties are wide-ranging, reflecting the importance of DNA Research in many aspects of health and disease, including; DNA Repair, DNA Replication, DNA Damage, Cancer, Chromosomal Instability, RNA and Nucleic Acids.
The group is open to all and is intended as a networking forum for past, present and future participants of Fusion Conferences as well as those interested in the related topics.
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
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Venue Rating
Currency
Address
Nearest Airport
The hotel is currently under construction and opens during fall 2021. We have wanted to contract with a property in the Riviera Maya for some time as it is a beautiful area of Mexico and has a very different vibe to the hustle and bustle of Cancun. Located just 8 miles from Tulum, this hidden gem is the perfect destination for those who love admiring, exploring or enjoying nature. Fiesta Americana Tulkal Riviera Maya will captivate your senses with unparalleled natural views, bold flavors, clear blue skies, the gentle touch of the cool breeze and the irresistible aromas of this tropical paradise. We have a feeling this is going to be a new favourite amongst our delegates.
Hotel facilities include;
Stretching from the fishing village of Puerto Morelos to the biosphere reserve of Sian Ka'an, the Mayan Riviera offers an unforgettable Caribbean coastline experience with beautiful white-sand beaches and brilliant turquoise colored water. This world-renowned paradise is home to mangroves and lagoons, ancient Mayan cities, ecological reserves and adventure parks, and the world's second largest coral reef.
The hotel is located just a few miles from Tulum, a town on the Caribbean coastline of Mexico’s Yucatán Peninsula. It’s known for its spectacluar beaches and well-preserved ruins of an ancient Mayan port city. The area also offers incredible cavern diving opportunties and beautiful cenotes to explore. We would highly recommend joining one of the group activities to Tulum or the Gran Cenote - they will make for an unforgettable conference experience!
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
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Cancun International airport is approximately 1hr 15minutes from the Fiesta Americana Tulkal Riviera Maya and is easily accessible from almost every country in the world with many major international airlines providing direct or interconnecting flights on a daily basis.
Airport transfer details and recommended suppliers will be available shorlty.
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
Chairs
Local activity details will be announced here soon.
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
Chairs
Group activity details will be announced here soon.
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
Chairs
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
Chairs
We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.
On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.
Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.
We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.
Please make sure your presentation adheres to the following guidelines.
Aspect Ratio: On Screen Show (16:9)
File Type: Please save your presentation in PPT, PPTS or Keynote format.
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
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We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.
Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you.
Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.
Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.
Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.
Download Abstract Template
27 Apr 2022 - 01 May 2022
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Riviera Maya, Mexico
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27 Apr 2022, 01 May 2022
#DRRSC22
Fiesta Americana Tulkal Riviera Maya, Riviera Maya, Mexico
Although conferences can boost productivity and enable research sucesses, we understand that registering for a conference may be challenging right now. Many researchers will be unable to register for a future conference of interest if thei...
More Information
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