The DNA damage response (DDR) is a multifaceted intracellular network that is affected by, and influences, myriad cellular components and processes, including chromatin structure, DNA replication, transcription and cell cycle progression. Failure to properly respond to DNA damage leads to genomic instability, which is associated with various human syndromes and causes many age-related diseases, particularly cancer. It is becoming increasingly clear that various proteins connected to the DDR represent attractive therapeutic targets for cancer and other diseases.

The conference will cover new and highly topical aspects of DDR research, ranging from detailed molecular mechanisms to disease connections and therapeutic applications. The meeting will also highlight how DDR processes are influenced by epigenetic factors that include post-translational modifications and chromatin state. Bringing together world-leading established scientists and young investigators, the conference will provide a forum for presentations and discussions on cutting-edge research. Every effort will be made to facilitate the exchange of ideas between participating scientists, which will enable new collaborations and thereby accelerate scientific discoveries.

Key Sessions: 

• Responses to DNA double-strand breaks
• DNA repair, DNA replication and chromatin
• Disease linkages and therapeutic applications

Target Audience

This conference will appeal to DNA repair, DNA-damage response and cell biology researchers worldwide, plus researchers, company employees and clinicians interested in how DNA repair and DDR processes impact on human health and disease, and therapeutic applications arising from DNA repair/DDR research. Researchers at all levels, from PhD students, post-docs, junior and senior PIs would find this meeting hugely relevant.
 

Although the programme has not yet been released, we are able to confirm that the overlapping session commences at 2:30pm on 03rd May and the conference will conclude on 06th May following breakfast.