The DNA of eukaryotic cells is organized into chromatin fibres, where the nucleosome is the basic repeating unit. Chromatin is thus at the core of fundamental processes such as gene regulation, stem cell fate determination and cancer. By and large, these topics have traditionally been covered by separated meetings. However, recent literature indicates that the boundaries among these various disciplines are becoming less clear. This meeting on "Epigenetics: from mechanisms to disease" will bring together scientists studying chromatin architecture, epigenetics, stem cell biology and cancer. The talks will cover a broad range of topics, including chromosome organisation, long-range interactions, chromatin assembly, stem cell regulation/differentiation, RNA-based mechanisms, transcription regulation, DNA methylation and hydroxymethylation.
Speakers have been selected to broadly reflect lessons learned from a variety of model organisms and experimental approaches, including single-cell omics and imaging, chromatin and 3D genome analysis. Young scientists will be able to present their work through a large number of short talks selected from submitted abstracts as well as through poster presentation. The program has also allocated ample time for exchanging ideas and discussing novel hypotheses at the end of each session, as well as time for informal interactions and networking.
Take advantage of this fantastic opportunity for students! Register an academic at the earlybird rate and bring a student for only $850. Unfortunately, Postdocs are not eligible for this offer. Both registration packages include; accommodation for the 28, 29 February and 01 March 2020 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Academic registrations must be completed by 8th November 2019. Once registered, please contact Emily Bicknell to obtain a special registration link for your student.
Confirmed Invited Speakers
Karen Adelman (Harvard Medical School)
Asifa Akhtar (Max Planck Institute of Immunobiology and Epigenetics)
Salvador Aznar Benitah (IRB Bracelona)
IMPACT OF HETEROCHROMATIN REGULATION IN ADULT STEM CELL FUNCTION AND MUTATIONAL BURDEN IN CANCER STEM CELLS
Roberto Bonasio (University of Pennsylvania)
Adrian Bracken (Trinity College Dublin)
PRC2 COMPLEXES IN DEVELOPMENT AND DISEASE
Anne Brunet (Stanford University)
CHANGES IN CHROMATIN STATES IN AGING NEURAL STEM CELLS
Victor Corces (Emory University)
Amanda Fisher (London Institute of Medical Sciences)
François Fuks (University of Brussels)
TRANSCRIPTOME-WIDE DISTRIBUTION AND FUNCTION OF RNA MODIFICATIONS
Yad Ghavi-Helm (Institute of Functional Genomics of Lyon - IGFL)
Cigall Kadoch (Dana Farber / Harvard Medical School)
PRC2 COMPLEXES IN DEVELOPMENT AND DISEASE
Robert Kingston (Mass. General Hospital)
Tony Kouzarides (The Gurdon Institute)
Jeannie Lee (Massachusetts General Hospital)
THE MANY FACES OF XIST RNA IN 3D
Geeta Narlikar (University of California, San Francisco)
THE ROLE OF PHASE-SEPARATION IN GENOME ORGANIZATION
Diego Pasini (University of Milan)
Rab Prinjha (GlaxoSmithKline)
DRUGGING TRANSCRIPTION: PROGRESS AND POTENTIAL FOR TREATING HUMAN DISEASES
Danny Reinberg (Howard Hughes Medical Institute)
THE EPIGENETIC STATUS OF SOME HISTONE POST-TRANSLATIONAL MODIFICATIONS
Anthony Schmitt (Arima Genomics)
Ramin Shiekhattar (University of Miami)
REGULATION OF THE CODING AND NONCODING GENOME BY INTEGRATOR
Ali Shilatifard (Northwestern University)
PRINCIPLES OF EPIGENETICS AND CHROMATIN IN DEVELOPMENT AND HUMAN DISEASE
Ting (C.-ting) Wu (Harvard Medical School)
SUCH A LOT OF GENOME TO SEE…
This conference will appeal to PhD students, post-doc and group leaders working in the field of chromatin architecture, epigenetics, stem cell biology and cancer. Scientists active in R&D of small, medium and big pharma or biotech companies.
The primary purpose of workshops is to enhance communication between junior and senior investigators. As mentioned in the executive summary, “Young scientists will have the opportunities to present their work through a large number of short talks selected from submitted abstracts as well as through poster presentation. The program has also allocated ample time for exchanging ideas and discussing novel hypothesis at the end of each session, as well as time for informal interactions and networking.
If you're interested in sponsoring this conference please contact us.